PT1948615E - Derivados de pirazol úteis para o tratamento de doenças ginecológicas - Google Patents
Derivados de pirazol úteis para o tratamento de doenças ginecológicas Download PDFInfo
- Publication number
- PT1948615E PT1948615E PT06809167T PT06809167T PT1948615E PT 1948615 E PT1948615 E PT 1948615E PT 06809167 T PT06809167 T PT 06809167T PT 06809167 T PT06809167 T PT 06809167T PT 1948615 E PT1948615 E PT 1948615E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- pyrazole derivatives
- derivatives useful
- gynaecological diseases
- gynaecological
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73509105P | 2005-11-08 | 2005-11-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1948615E true PT1948615E (pt) | 2012-02-03 |
Family
ID=37909834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT06809167T PT1948615E (pt) | 2005-11-08 | 2006-10-26 | Derivados de pirazol úteis para o tratamento de doenças ginecológicas |
Country Status (35)
Country | Link |
---|---|
US (2) | US7309712B2 (pt) |
EP (1) | EP1948615B1 (pt) |
JP (1) | JP4234786B1 (pt) |
KR (1) | KR100997595B1 (pt) |
CN (1) | CN101304974A (pt) |
AP (1) | AP2008004463A0 (pt) |
AR (1) | AR056780A1 (pt) |
AT (1) | ATE537150T1 (pt) |
AU (1) | AU2006313478A1 (pt) |
BR (1) | BRPI0618630A2 (pt) |
CA (1) | CA2628844C (pt) |
CR (1) | CR9959A (pt) |
CY (1) | CY1112286T1 (pt) |
DK (1) | DK1948615T3 (pt) |
DO (1) | DOP2006000245A (pt) |
EA (1) | EA014693B1 (pt) |
EC (1) | ECSP088431A (pt) |
ES (1) | ES2376252T3 (pt) |
GT (1) | GT200600478A (pt) |
HN (1) | HN2006037713A (pt) |
IL (1) | IL190806A0 (pt) |
MA (1) | MA29940B1 (pt) |
NL (1) | NL2000299C2 (pt) |
NO (1) | NO20082504L (pt) |
PE (1) | PE20070642A1 (pt) |
PL (1) | PL1948615T3 (pt) |
PT (1) | PT1948615E (pt) |
RS (1) | RS20080191A (pt) |
SI (1) | SI1948615T1 (pt) |
TN (1) | TNSN08202A1 (pt) |
TW (1) | TWI321563B (pt) |
UA (1) | UA90763C2 (pt) |
UY (1) | UY29904A1 (pt) |
WO (1) | WO2007054770A2 (pt) |
ZA (1) | ZA200803670B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9710536A (pt) | 1996-07-24 | 1999-08-17 | Warner Lambert Co | Isobutilgaba e seus derivados para o tratamento da dor |
SI1948615T1 (sl) * | 2005-11-08 | 2012-02-29 | Pfizer Ltd | Derivati pirazola, uporabni za zdravljenje ginekoloških obolenj |
WO2008014199A2 (en) | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the cb2 receptor |
CA2664310A1 (en) | 2006-09-25 | 2008-04-03 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
WO2008135824A1 (en) * | 2007-05-02 | 2008-11-13 | Pfizer Limited | Oxyalkylpyrazole compounds useful in therapy |
WO2009061652A1 (en) | 2007-11-07 | 2009-05-14 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
SG176464A1 (en) | 2008-05-09 | 2011-12-29 | Agency Science Tech & Res | Diagnosis and treatment of kawasaki disease |
EP2283001A2 (en) * | 2008-05-13 | 2011-02-16 | Boehringer Ingelheim International GmbH | Sulfone compounds which modulate the cb2 receptor |
US8178568B2 (en) | 2008-07-10 | 2012-05-15 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the CB2 receptor |
CA2737639A1 (en) | 2008-09-25 | 2010-04-01 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the cb2 receptor |
US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
EP2443107B1 (en) | 2009-06-16 | 2018-08-08 | Boehringer Ingelheim International GmbH | Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor |
JP2013505295A (ja) | 2009-09-22 | 2013-02-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を選択的に調節する化合物 |
US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
US20110136815A1 (en) * | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
JP2013517271A (ja) | 2010-01-15 | 2013-05-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節する化合物 |
EP2542539B1 (en) | 2010-03-05 | 2014-02-26 | Boehringer Ingelheim International GmbH | Tetrazole compounds which selectively modulate the cb2 receptor |
US20110263606A1 (en) * | 2010-04-26 | 2011-10-27 | Horst Zerbe | Solid oral dosage forms comprising tadalafil |
JP5746764B2 (ja) | 2010-07-22 | 2015-07-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節する化合物 |
EP2803668A1 (en) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles |
KR20210076069A (ko) * | 2018-10-18 | 2021-06-23 | 난징 산홈 팔마세우티칼 컴퍼니 리미티드 | TGF-βR1 억제제로서의 화합물 및 이의 적용 |
RU2711615C1 (ru) * | 2019-09-12 | 2020-01-17 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. Отта" | Способ лечения эндометриоза на основании экспериментальной модели у крыс |
CN111269097B (zh) * | 2020-04-02 | 2023-02-17 | 苏州爱玛特生物科技有限公司 | 一种多元环双取代的1,3-丙二酮类化合物的合成方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6281638A (ja) * | 1985-10-07 | 1987-04-15 | Fuji Photo Film Co Ltd | ハロゲン化銀カラ−写真感光材料 |
JPS63313784A (ja) * | 1987-03-12 | 1988-12-21 | Zeria Shinyaku Kogyo Kk | 新規ピラゾール誘導体およびその製造法ならびにこれを有効成分とする抗潰瘍剤 |
DE4414792A1 (de) * | 1993-08-11 | 1995-02-16 | Bayer Ag | Arzneimittel enthaltend 1-Thiocarbamoyl-5-hydroxypyrazolen und deren Verwendung als Mittel zur Bekämpfung des septischen Schocks |
EE05400B1 (et) * | 2001-04-10 | 2011-04-15 | Pfizer Inc. | Prasoolderivaadid, neid v?i nende farmatseutiliselt vastuv?etavaid sooli, solvaate v?i derivaate sisaldavad farmatseutilised kompositsioonid, nende kasutamine ning meetodid nende valmistamiseks |
GB0229618D0 (en) * | 2002-12-19 | 2003-01-22 | Cancer Rec Tech Ltd | Pyrazole compounds |
SI1948615T1 (sl) * | 2005-11-08 | 2012-02-29 | Pfizer Ltd | Derivati pirazola, uporabni za zdravljenje ginekoloških obolenj |
-
2006
- 2006-10-26 SI SI200631237T patent/SI1948615T1/sl unknown
- 2006-10-26 CN CNA2006800416684A patent/CN101304974A/zh active Pending
- 2006-10-26 AP AP2008004463A patent/AP2008004463A0/xx unknown
- 2006-10-26 PT PT06809167T patent/PT1948615E/pt unknown
- 2006-10-26 BR BRPI0618630-0A patent/BRPI0618630A2/pt not_active IP Right Cessation
- 2006-10-26 EP EP06809167A patent/EP1948615B1/en active Active
- 2006-10-26 EA EA200801053A patent/EA014693B1/ru not_active IP Right Cessation
- 2006-10-26 JP JP2008539519A patent/JP4234786B1/ja not_active Expired - Fee Related
- 2006-10-26 UA UAA200805973A patent/UA90763C2/ru unknown
- 2006-10-26 CA CA2628844A patent/CA2628844C/en not_active Expired - Fee Related
- 2006-10-26 AT AT06809167T patent/ATE537150T1/de active
- 2006-10-26 PL PL06809167T patent/PL1948615T3/pl unknown
- 2006-10-26 WO PCT/IB2006/003080 patent/WO2007054770A2/en active Application Filing
- 2006-10-26 AU AU2006313478A patent/AU2006313478A1/en not_active Abandoned
- 2006-10-26 DK DK06809167.7T patent/DK1948615T3/da active
- 2006-10-26 KR KR1020087010982A patent/KR100997595B1/ko not_active IP Right Cessation
- 2006-10-26 RS RSP-2008/0191A patent/RS20080191A/sr unknown
- 2006-10-26 ES ES06809167T patent/ES2376252T3/es active Active
- 2006-11-02 NL NL2000299A patent/NL2000299C2/nl not_active IP Right Cessation
- 2006-11-03 US US11/592,574 patent/US7309712B2/en not_active Expired - Fee Related
- 2006-11-06 PE PE2006001366A patent/PE20070642A1/es not_active Application Discontinuation
- 2006-11-07 GT GT200600478A patent/GT200600478A/es unknown
- 2006-11-07 HN HN2006037713A patent/HN2006037713A/es unknown
- 2006-11-07 TW TW095141158A patent/TWI321563B/zh active
- 2006-11-07 AR ARP060104881A patent/AR056780A1/es unknown
- 2006-11-08 DO DO2006000245A patent/DOP2006000245A/es unknown
- 2006-11-08 UY UY29904A patent/UY29904A1/es not_active Application Discontinuation
-
2007
- 2007-10-11 US US11/870,451 patent/US7425569B2/en not_active Expired - Fee Related
-
2008
- 2008-04-10 IL IL190806A patent/IL190806A0/en unknown
- 2008-04-25 ZA ZA200803670A patent/ZA200803670B/xx unknown
- 2008-05-06 EC EC2008008431A patent/ECSP088431A/es unknown
- 2008-05-07 TN TNP2008000202A patent/TNSN08202A1/fr unknown
- 2008-05-08 MA MA30910A patent/MA29940B1/fr unknown
- 2008-05-08 CR CR9959A patent/CR9959A/es not_active Application Discontinuation
- 2008-06-05 NO NO20082504A patent/NO20082504L/no not_active Application Discontinuation
-
2012
- 2012-01-27 CY CY20121100096T patent/CY1112286T1/el unknown
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