DK1948615T3 - Til behandling af gynækologiske sygdomme egnede pyrazolderivater - Google Patents

Til behandling af gynækologiske sygdomme egnede pyrazolderivater

Info

Publication number
DK1948615T3
DK1948615T3 DK06809167.7T DK06809167T DK1948615T3 DK 1948615 T3 DK1948615 T3 DK 1948615T3 DK 06809167 T DK06809167 T DK 06809167T DK 1948615 T3 DK1948615 T3 DK 1948615T3
Authority
DK
Denmark
Prior art keywords
treatment
pyrazole derivatives
gynecological diseases
suitable pyrazole
gynecological
Prior art date
Application number
DK06809167.7T
Other languages
English (en)
Inventor
Paul Anthony Bradley
Kevin Neil Dack
Patrick Stephen Johnson
Sarah Elizabeth Skerratt
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of DK1948615T3 publication Critical patent/DK1948615T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18One oxygen or sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
DK06809167.7T 2005-11-08 2006-10-26 Til behandling af gynækologiske sygdomme egnede pyrazolderivater DK1948615T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73509105P 2005-11-08 2005-11-08
PCT/IB2006/003080 WO2007054770A2 (en) 2005-11-08 2006-10-26 Pyrazole derivatives and their medical use

Publications (1)

Publication Number Publication Date
DK1948615T3 true DK1948615T3 (da) 2012-02-06

Family

ID=37909834

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06809167.7T DK1948615T3 (da) 2005-11-08 2006-10-26 Til behandling af gynækologiske sygdomme egnede pyrazolderivater

Country Status (35)

Country Link
US (2) US7309712B2 (da)
EP (1) EP1948615B1 (da)
JP (1) JP4234786B1 (da)
KR (1) KR100997595B1 (da)
CN (1) CN101304974A (da)
AP (1) AP2008004463A0 (da)
AR (1) AR056780A1 (da)
AT (1) ATE537150T1 (da)
AU (1) AU2006313478A1 (da)
BR (1) BRPI0618630A2 (da)
CA (1) CA2628844C (da)
CR (1) CR9959A (da)
CY (1) CY1112286T1 (da)
DK (1) DK1948615T3 (da)
DO (1) DOP2006000245A (da)
EA (1) EA014693B1 (da)
EC (1) ECSP088431A (da)
ES (1) ES2376252T3 (da)
GT (1) GT200600478A (da)
HN (1) HN2006037713A (da)
IL (1) IL190806A0 (da)
MA (1) MA29940B1 (da)
NL (1) NL2000299C2 (da)
NO (1) NO20082504L (da)
PE (1) PE20070642A1 (da)
PL (1) PL1948615T3 (da)
PT (1) PT1948615E (da)
RS (1) RS20080191A (da)
SI (1) SI1948615T1 (da)
TN (1) TNSN08202A1 (da)
TW (1) TWI321563B (da)
UA (1) UA90763C2 (da)
UY (1) UY29904A1 (da)
WO (1) WO2007054770A2 (da)
ZA (1) ZA200803670B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69722426T3 (de) 1996-07-24 2015-05-07 Warner-Lambert Company LLC (n.Ges. des Staates Delaware) Isobutylgaba und dessen derivate zur schmerzbehandlung
DK1948615T3 (da) * 2005-11-08 2012-02-06 Pfizer Ltd Til behandling af gynækologiske sygdomme egnede pyrazolderivater
US7935715B2 (en) 2006-07-28 2011-05-03 Boehringer Ingelheim International Gmbh Compounds which modulate the CB2 receptor
JP5030114B2 (ja) 2006-09-25 2012-09-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Cb2受容体をモジュレートする化合物
WO2008135824A1 (en) * 2007-05-02 2008-11-13 Pfizer Limited Oxyalkylpyrazole compounds useful in therapy
US8546563B2 (en) 2007-11-07 2013-10-01 Boehringer Ingelheim International Gmbh Compounds which modulate the CB2 receptor
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
WO2009140089A2 (en) * 2008-05-13 2009-11-19 Boehringer Ingelheim International Gmbh Sulfone compounds which modulate the cb2 receptor
CA2730037A1 (en) 2008-07-10 2010-01-14 Boehringer Ingelheim International Gmbh Sulfone compounds which modulate the cb2 receptor
BRPI0919172A2 (pt) 2008-09-25 2015-12-15 Boehringer Ingelheim Int compostos os quais modulam seletivamente o receptor de cb2
US8299103B2 (en) 2009-06-15 2012-10-30 Boehringer Ingelheim International Gmbh Compounds which selectively modulate the CB2 receptor
EP2443107B1 (en) 2009-06-16 2018-08-08 Boehringer Ingelheim International GmbH Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor
WO2011037795A1 (en) 2009-09-22 2011-03-31 Boehringer Ingelheim International Gmbh Compounds which selectively modulate the cb2 receptor
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
EP2523936A1 (en) 2010-01-15 2012-11-21 Boehringer Ingelheim International GmbH Compounds which modulate the cb2 receptor
WO2011109324A1 (en) 2010-03-05 2011-09-09 Boehringer Ingelheim International Gmbh Tetrazole compounds which selectively modulate the cb2 receptor
US20110263606A1 (en) * 2010-04-26 2011-10-27 Horst Zerbe Solid oral dosage forms comprising tadalafil
JP5746764B2 (ja) 2010-07-22 2015-07-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Cb2受容体を調節する化合物
EP2803668A1 (en) 2013-05-17 2014-11-19 Boehringer Ingelheim International Gmbh Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
AU2019362242A1 (en) * 2018-10-18 2021-05-27 Nanjing Sanhome Pharmaceutical Co., Ltd. Compound as TGF-β R1 inhibitor and application thereof
RU2711615C1 (ru) * 2019-09-12 2020-01-17 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. Отта" Способ лечения эндометриоза на основании экспериментальной модели у крыс
CN111269097B (zh) * 2020-04-02 2023-02-17 苏州爱玛特生物科技有限公司 一种多元环双取代的1,3-丙二酮类化合物的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6281638A (ja) * 1985-10-07 1987-04-15 Fuji Photo Film Co Ltd ハロゲン化銀カラ−写真感光材料
JPS63313784A (ja) * 1987-03-12 1988-12-21 Zeria Shinyaku Kogyo Kk 新規ピラゾール誘導体およびその製造法ならびにこれを有効成分とする抗潰瘍剤
DE4414792A1 (de) * 1993-08-11 1995-02-16 Bayer Ag Arzneimittel enthaltend 1-Thiocarbamoyl-5-hydroxypyrazolen und deren Verwendung als Mittel zur Bekämpfung des septischen Schocks
RS51166B (sr) * 2001-04-10 2010-10-31 Pfizer Inc. Derivati pirazola za tretiranje hiv
GB0229618D0 (en) * 2002-12-19 2003-01-22 Cancer Rec Tech Ltd Pyrazole compounds
DK1948615T3 (da) * 2005-11-08 2012-02-06 Pfizer Ltd Til behandling af gynækologiske sygdomme egnede pyrazolderivater

Also Published As

Publication number Publication date
AP2008004463A0 (en) 2008-06-30
TNSN08202A1 (fr) 2009-10-30
WO2007054770A3 (en) 2007-10-04
PT1948615E (pt) 2012-02-03
CA2628844A1 (en) 2007-05-18
EP1948615B1 (en) 2011-12-14
CA2628844C (en) 2011-12-06
CN101304974A (zh) 2008-11-12
MA29940B1 (fr) 2008-11-03
EP1948615A2 (en) 2008-07-30
US7425569B2 (en) 2008-09-16
JP2009514938A (ja) 2009-04-09
KR100997595B1 (ko) 2010-11-30
IL190806A0 (en) 2008-11-03
WO2007054770A2 (en) 2007-05-18
US20070105909A1 (en) 2007-05-10
AR056780A1 (es) 2007-10-24
TW200804295A (en) 2008-01-16
HN2006037713A (es) 2010-06-09
EA014693B1 (ru) 2010-12-30
NO20082504L (no) 2008-06-05
PL1948615T3 (pl) 2012-04-30
DOP2006000245A (es) 2007-06-30
UA90763C2 (ru) 2010-05-25
GT200600478A (es) 2007-06-08
CY1112286T1 (el) 2015-12-09
NL2000299C2 (nl) 2007-11-20
JP4234786B1 (ja) 2009-03-04
CR9959A (es) 2008-08-01
KR20080056761A (ko) 2008-06-23
SI1948615T1 (sl) 2012-02-29
ZA200803670B (en) 2009-03-25
US20080085919A1 (en) 2008-04-10
AU2006313478A1 (en) 2007-05-18
RS20080191A (en) 2009-07-15
ES2376252T3 (es) 2012-03-12
EA200801053A1 (ru) 2008-10-30
ATE537150T1 (de) 2011-12-15
BRPI0618630A2 (pt) 2011-09-06
PE20070642A1 (es) 2007-08-24
ECSP088431A (es) 2008-06-30
NL2000299A1 (nl) 2007-05-09
UY29904A1 (es) 2007-06-29
TWI321563B (en) 2010-03-11
US7309712B2 (en) 2007-12-18

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