UA90285C2 - Производные гидантоина, полезные как ингибиторы металлопротеиназ - Google Patents

Производные гидантоина, полезные как ингибиторы металлопротеиназ

Info

Publication number
UA90285C2
UA90285C2 UAA200706657A UAA200706657A UA90285C2 UA 90285 C2 UA90285 C2 UA 90285C2 UA A200706657 A UAA200706657 A UA A200706657A UA A200706657 A UAA200706657 A UA A200706657A UA 90285 C2 UA90285 C2 UA 90285C2
Authority
UA
Ukraine
Prior art keywords
mmp inhibitors
derivatives useful
hydantoin derivatives
pharmaceutical compositions
useful
Prior art date
Application number
UAA200706657A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Балинт Габос
Микаэль Лундквист
Аф Розеншэльд Магнус Мунк
Игор Шамовски
Павол Златоидски
Original Assignee
Астразенека Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астразенека Аб filed Critical Астразенека Аб
Publication of UA90285C2 publication Critical patent/UA90285C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
UAA200706657A 2004-12-17 2005-12-14 Производные гидантоина, полезные как ингибиторы металлопротеиназ UA90285C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0403085A SE0403085D0 (sv) 2004-12-17 2004-12-17 Novel componds

Publications (1)

Publication Number Publication Date
UA90285C2 true UA90285C2 (ru) 2010-04-26

Family

ID=34075235

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200706657A UA90285C2 (ru) 2004-12-17 2005-12-14 Производные гидантоина, полезные как ингибиторы металлопротеиназ

Country Status (23)

Country Link
US (2) US7655664B2 (https=)
EP (1) EP1831199B1 (https=)
JP (1) JP2008524210A (https=)
KR (1) KR20070090924A (https=)
CN (1) CN101119987A (https=)
AR (1) AR051795A1 (https=)
AT (1) ATE545642T1 (https=)
AU (1) AU2005317286B2 (https=)
BR (1) BRPI0517035A (https=)
CA (1) CA2590845A1 (https=)
ES (1) ES2380670T3 (https=)
IL (1) IL183599A (https=)
MX (1) MX2007007023A (https=)
MY (1) MY147770A (https=)
NO (1) NO20073572L (https=)
NZ (1) NZ555831A (https=)
RU (1) RU2376301C2 (https=)
SA (1) SA05260409B1 (https=)
SE (1) SE0403085D0 (https=)
TW (1) TW200635917A (https=)
UA (1) UA90285C2 (https=)
WO (1) WO2006065215A1 (https=)
ZA (1) ZA200705075B (https=)

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US7648992B2 (en) * 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
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KR101271219B1 (ko) * 2011-01-27 2013-06-07 광주과학기술원 신규한 하이단토인 유도체 및 이의 용도
US9975880B2 (en) * 2013-12-31 2018-05-22 Ipsen Pharma S.A.S. Imidazolidine-2,4-dione dervatives
US20200268728A1 (en) 2016-12-20 2020-08-27 Sumitomo Dainippon Pharma Co., Ltd. Drug targeting cancer stem cell
TWI901650B (zh) * 2020-03-26 2025-10-21 匈牙利商羅特格登公司 啶及吡啶并〔３，４－ｃ〕嗒衍生物
CA3244639A1 (en) 2021-12-28 2025-06-13 Nippon Shinyaku Co., Ltd. Indazole compound and pharmaceutical
KR20250011204A (ko) * 2022-05-30 2025-01-21 시노허브 파마슈티컬 씨오., 엘티디 유착 관련 질환을 예방 치료하는 약물의 제조에서 테트라히드로나프티리딘 유도체의 응용

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SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
TW200740769A (en) * 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
AU2005317286A1 (en) 2006-06-22
BRPI0517035A (pt) 2008-09-30
NZ555831A (en) 2011-01-28
IL183599A (en) 2012-02-29
RU2376301C2 (ru) 2009-12-20
NO20073572L (no) 2007-09-12
MX2007007023A (es) 2007-09-11
SA05260409B1 (ar) 2009-03-14
JP2008524210A (ja) 2008-07-10
RU2007126746A (ru) 2009-01-27
CA2590845A1 (en) 2006-06-22
SE0403085D0 (sv) 2004-12-17
TW200635917A (en) 2006-10-16
ATE545642T1 (de) 2012-03-15
EP1831199B1 (en) 2012-02-15
MY147770A (en) 2013-01-31
US20080293743A1 (en) 2008-11-27
AR051795A1 (es) 2007-02-07
ZA200705075B (en) 2008-12-31
EP1831199A1 (en) 2007-09-12
US7655664B2 (en) 2010-02-02
IL183599A0 (en) 2007-09-20
CN101119987A (zh) 2008-02-06
ES2380670T3 (es) 2012-05-17
KR20070090924A (ko) 2007-09-06
AU2005317286B2 (en) 2009-02-05
WO2006065215A1 (en) 2006-06-22
US20100256166A1 (en) 2010-10-07

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