AR051795A1 - Derivados de hidantoina inhibidores de metaloproteinasas - Google Patents

Derivados de hidantoina inhibidores de metaloproteinasas

Info

Publication number
AR051795A1
AR051795A1 ARP050105273A ARP050105273A AR051795A1 AR 051795 A1 AR051795 A1 AR 051795A1 AR P050105273 A ARP050105273 A AR P050105273A AR P050105273 A ARP050105273 A AR P050105273A AR 051795 A1 AR051795 A1 AR 051795A1
Authority
AR
Argentina
Prior art keywords
cyclopropyl
hydantoin derivatives
inhibitors
metaloproteinase inhibitors
metaloproteinase
Prior art date
Application number
ARP050105273A
Other languages
English (en)
Spanish (es)
Inventor
Balint Gabos
Michael Lundkvist
Af Rosenschoeld Magnus Munck
Igor Shamovsky
Pavol Zlatoidsky
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR051795A1 publication Critical patent/AR051795A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ARP050105273A 2004-12-17 2005-12-15 Derivados de hidantoina inhibidores de metaloproteinasas AR051795A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0403085A SE0403085D0 (sv) 2004-12-17 2004-12-17 Novel componds

Publications (1)

Publication Number Publication Date
AR051795A1 true AR051795A1 (es) 2007-02-07

Family

ID=34075235

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050105273A AR051795A1 (es) 2004-12-17 2005-12-15 Derivados de hidantoina inhibidores de metaloproteinasas

Country Status (23)

Country Link
US (2) US7655664B2 (https=)
EP (1) EP1831199B1 (https=)
JP (1) JP2008524210A (https=)
KR (1) KR20070090924A (https=)
CN (1) CN101119987A (https=)
AR (1) AR051795A1 (https=)
AT (1) ATE545642T1 (https=)
AU (1) AU2005317286B2 (https=)
BR (1) BRPI0517035A (https=)
CA (1) CA2590845A1 (https=)
ES (1) ES2380670T3 (https=)
IL (1) IL183599A (https=)
MX (1) MX2007007023A (https=)
MY (1) MY147770A (https=)
NO (1) NO20073572L (https=)
NZ (1) NZ555831A (https=)
RU (1) RU2376301C2 (https=)
SA (1) SA05260409B1 (https=)
SE (1) SE0403085D0 (https=)
TW (1) TW200635917A (https=)
UA (1) UA90285C2 (https=)
WO (1) WO2006065215A1 (https=)
ZA (1) ZA200705075B (https=)

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US7648992B2 (en) * 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
EP1859356B1 (en) * 2005-03-16 2019-07-10 Sensus Metering Systems Inc. Method, system, apparatus, and computer program product for determining a physical location of a sensor
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TW200740769A (en) * 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
KR101271219B1 (ko) * 2011-01-27 2013-06-07 광주과학기술원 신규한 하이단토인 유도체 및 이의 용도
US9975880B2 (en) * 2013-12-31 2018-05-22 Ipsen Pharma S.A.S. Imidazolidine-2,4-dione dervatives
US20200268728A1 (en) 2016-12-20 2020-08-27 Sumitomo Dainippon Pharma Co., Ltd. Drug targeting cancer stem cell
TWI901650B (zh) * 2020-03-26 2025-10-21 匈牙利商羅特格登公司 啶及吡啶并〔３，４－ｃ〕嗒衍生物
CA3244639A1 (en) 2021-12-28 2025-06-13 Nippon Shinyaku Co., Ltd. Indazole compound and pharmaceutical
KR20250011204A (ko) * 2022-05-30 2025-01-21 시노허브 파마슈티컬 씨오., 엘티디 유착 관련 질환을 예방 치료하는 약물의 제조에서 테트라히드로나프티리딘 유도체의 응용

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SE0401763D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Compounds
SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
TW200740769A (en) * 2006-03-16 2007-11-01 Astrazeneca Ab Novel process
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
AU2005317286A1 (en) 2006-06-22
BRPI0517035A (pt) 2008-09-30
NZ555831A (en) 2011-01-28
IL183599A (en) 2012-02-29
RU2376301C2 (ru) 2009-12-20
NO20073572L (no) 2007-09-12
MX2007007023A (es) 2007-09-11
SA05260409B1 (ar) 2009-03-14
JP2008524210A (ja) 2008-07-10
RU2007126746A (ru) 2009-01-27
CA2590845A1 (en) 2006-06-22
SE0403085D0 (sv) 2004-12-17
TW200635917A (en) 2006-10-16
ATE545642T1 (de) 2012-03-15
EP1831199B1 (en) 2012-02-15
MY147770A (en) 2013-01-31
US20080293743A1 (en) 2008-11-27
ZA200705075B (en) 2008-12-31
EP1831199A1 (en) 2007-09-12
US7655664B2 (en) 2010-02-02
IL183599A0 (en) 2007-09-20
CN101119987A (zh) 2008-02-06
UA90285C2 (ru) 2010-04-26
ES2380670T3 (es) 2012-05-17
KR20070090924A (ko) 2007-09-06
AU2005317286B2 (en) 2009-02-05
WO2006065215A1 (en) 2006-06-22
US20100256166A1 (en) 2010-10-07

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