UA88634C2 - Quaternized quinuclidine esters - Google Patents

Quaternized quinuclidine esters

Info

Publication number
UA88634C2
UA88634C2 UAA200610595A UAA200610595A UA88634C2 UA 88634 C2 UA88634 C2 UA 88634C2 UA A200610595 A UAA200610595 A UA A200610595A UA A200610595 A UAA200610595 A UA A200610595A UA 88634 C2 UA88634 C2 UA 88634C2
Authority
UA
Ukraine
Prior art keywords
compounds
quaternized
quinuclidine esters
urological
respiratory
Prior art date
Application number
UAA200610595A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Форнер Мария Долорс Фернандес
Киньонес Мария Прат
Альберо Мария Антония Буил
Original Assignee
Алмиралл Продесфарма, Са
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Алмиралл Продесфарма, Са filed Critical Алмиралл Продесфарма, Са
Publication of UA88634C2 publication Critical patent/UA88634C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
UAA200610595A 2004-03-15 2005-10-03 Quaternized quinuclidine esters UA88634C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200400638A ES2239546B1 (es) 2004-03-15 2004-03-15 Nuevos esteres de quinuclidina cuaternizados.

Publications (1)

Publication Number Publication Date
UA88634C2 true UA88634C2 (en) 2009-11-10

Family

ID=34955916

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200610595A UA88634C2 (en) 2004-03-15 2005-10-03 Quaternized quinuclidine esters

Country Status (30)

Country Link
US (1) US20080214600A1 (enExample)
EP (1) EP1725552B1 (enExample)
JP (1) JP2007529444A (enExample)
KR (1) KR20070003940A (enExample)
CN (1) CN1930158A (enExample)
AR (1) AR048004A1 (enExample)
AT (1) ATE399166T1 (enExample)
AU (1) AU2005223310A1 (enExample)
BR (1) BRPI0508177A (enExample)
CA (1) CA2560157A1 (enExample)
CY (1) CY1108324T1 (enExample)
DE (1) DE602005007714D1 (enExample)
DK (1) DK1725552T3 (enExample)
EC (1) ECSP066770A (enExample)
ES (2) ES2239546B1 (enExample)
HR (1) HRP20080338T3 (enExample)
IL (1) IL177341A0 (enExample)
MY (1) MY142036A (enExample)
NO (1) NO20064659L (enExample)
NZ (1) NZ548583A (enExample)
PE (1) PE20060005A1 (enExample)
PL (1) PL1725552T3 (enExample)
PT (1) PT1725552E (enExample)
RS (1) RS50566B (enExample)
RU (1) RU2382041C2 (enExample)
SI (1) SI1725552T1 (enExample)
TW (1) TW200604196A (enExample)
UA (1) UA88634C2 (enExample)
WO (1) WO2005090342A1 (enExample)
ZA (1) ZA200605931B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
ES2298049B1 (es) * 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
JP2010519193A (ja) * 2007-02-15 2010-06-03 アージェンタ ディスカバリー リミテッド M3ムスカリン受容体としての複素環式誘導体
KR101517574B1 (ko) 2007-09-07 2015-05-07 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 무스카린 수용체 길항제로서 유용한 구아니딘을 함유하는 화합물
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
JP2011506477A (ja) 2007-12-14 2011-03-03 セラヴァンス, インコーポレーテッド ムスカリン受容体拮抗薬として有用なアミジン含有化合物
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
KR101290893B1 (ko) 2009-04-09 2013-07-29 노파르티스 아게 피롤리디늄 염의 제조 방법
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
TW201439089A (zh) * 2012-12-05 2014-10-16 Chiesi Farma Spa 新穎化合物
CN103755698A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一锅法制备阿地溴铵的工艺
CN103755699A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一种2-羟基-2,2-二噻吩-2-基乙酸-1-氮杂二环[2,2,2]辛-3(r)-基酯制备方法
KR101511090B1 (ko) 2014-04-24 2015-04-10 고려대학교 산학협력단 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
NO2005012I1 (no) * 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin og farmasoytisk akseptable salter derav
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
NZ526674A (en) * 2000-12-28 2005-03-24 Almirall Prodesfarma Ag Novel quinuclidine derivatives and medicinal compositions containing the same
NZ532283A (en) * 2001-10-17 2005-06-24 Ucb S Quinuclidine derivatives, processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
PE20060005A1 (es) 2006-01-28
DK1725552T3 (da) 2008-10-13
HRP20080338T3 (hr) 2008-07-31
CY1108324T1 (el) 2014-02-12
ES2307168T3 (es) 2008-11-16
KR20070003940A (ko) 2007-01-05
EP1725552B1 (en) 2008-06-25
ZA200605931B (en) 2007-11-28
SI1725552T1 (sl) 2008-10-31
EP1725552A1 (en) 2006-11-29
ES2239546A1 (es) 2005-09-16
AU2005223310A1 (en) 2005-09-29
TW200604196A (en) 2006-02-01
AR048004A1 (es) 2006-03-15
PL1725552T3 (pl) 2008-12-31
ES2239546B1 (es) 2006-12-01
ECSP066770A (es) 2006-11-16
RU2382041C2 (ru) 2010-02-20
RS50566B (sr) 2010-05-07
ATE399166T1 (de) 2008-07-15
WO2005090342A1 (en) 2005-09-29
NO20064659L (no) 2006-12-13
PT1725552E (pt) 2008-09-18
BRPI0508177A (pt) 2007-08-07
CA2560157A1 (en) 2005-09-29
MY142036A (en) 2010-08-16
IL177341A0 (en) 2006-12-10
CN1930158A (zh) 2007-03-14
JP2007529444A (ja) 2007-10-25
US20080214600A1 (en) 2008-09-04
DE602005007714D1 (de) 2008-08-07
HK1101855A1 (en) 2007-10-26
NZ548583A (en) 2010-05-28
RU2006136085A (ru) 2008-04-27

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