PT1725552E - Novos ésteres de quinuclidina quartenizados - Google Patents

Novos ésteres de quinuclidina quartenizados Download PDF

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Publication number
PT1725552E
PT1725552E PT05729711T PT05729711T PT1725552E PT 1725552 E PT1725552 E PT 1725552E PT 05729711 T PT05729711 T PT 05729711T PT 05729711 T PT05729711 T PT 05729711T PT 1725552 E PT1725552 E PT 1725552E
Authority
PT
Portugal
Prior art keywords
quinuclidine esters
new
new quaternized
esters
quaternized quinuclidine
Prior art date
Application number
PT05729711T
Other languages
English (en)
Portuguese (pt)
Inventor
Maria Antonia Buil Albero
Maria Dolors Fernandez Forner
Maria Prat Quinones
Original Assignee
Almirall Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Lab filed Critical Almirall Lab
Publication of PT1725552E publication Critical patent/PT1725552E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT05729711T 2004-03-15 2005-03-10 Novos ésteres de quinuclidina quartenizados PT1725552E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200400638A ES2239546B1 (es) 2004-03-15 2004-03-15 Nuevos esteres de quinuclidina cuaternizados.

Publications (1)

Publication Number Publication Date
PT1725552E true PT1725552E (pt) 2008-09-18

Family

ID=34955916

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05729711T PT1725552E (pt) 2004-03-15 2005-03-10 Novos ésteres de quinuclidina quartenizados

Country Status (30)

Country Link
US (1) US20080214600A1 (enExample)
EP (1) EP1725552B1 (enExample)
JP (1) JP2007529444A (enExample)
KR (1) KR20070003940A (enExample)
CN (1) CN1930158A (enExample)
AR (1) AR048004A1 (enExample)
AT (1) ATE399166T1 (enExample)
AU (1) AU2005223310A1 (enExample)
BR (1) BRPI0508177A (enExample)
CA (1) CA2560157A1 (enExample)
CY (1) CY1108324T1 (enExample)
DE (1) DE602005007714D1 (enExample)
DK (1) DK1725552T3 (enExample)
EC (1) ECSP066770A (enExample)
ES (2) ES2239546B1 (enExample)
HR (1) HRP20080338T3 (enExample)
IL (1) IL177341A0 (enExample)
MY (1) MY142036A (enExample)
NO (1) NO20064659L (enExample)
NZ (1) NZ548583A (enExample)
PE (1) PE20060005A1 (enExample)
PL (1) PL1725552T3 (enExample)
PT (1) PT1725552E (enExample)
RS (1) RS50566B (enExample)
RU (1) RU2382041C2 (enExample)
SI (1) SI1725552T1 (enExample)
TW (1) TW200604196A (enExample)
UA (1) UA88634C2 (enExample)
WO (1) WO2005090342A1 (enExample)
ZA (1) ZA200605931B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
ES2298049B1 (es) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
MX2009008323A (es) * 2007-02-15 2009-08-13 Argenta Discovery Ltd Derivados heterociclicos como receptores muscarinicos m3.
BRPI0816219B8 (pt) 2007-09-07 2021-05-25 Theravance Biopharma R&D Ip Llc compostos contendo guanidina úteis como antagonistas de receptor muscarínico, composição farmacêutica e uso
CA2608561A1 (en) * 2007-10-29 2009-04-29 Carl Paluszkiewicz Motorcycle wind deflector accessory support
EP2222637A1 (en) 2007-12-14 2010-09-01 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
JP5902612B2 (ja) 2009-04-09 2016-04-13 ノバルティス アーゲー ピロリジニウム塩の調製方法
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
HK1212986A1 (zh) * 2012-12-05 2016-06-24 奇斯药制品公司 作为pde4-抑制剂的苯基乙基吡啶衍生物
CN103755698A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一锅法制备阿地溴铵的工艺
CN103755699A (zh) * 2014-01-06 2014-04-30 万特制药(海南)有限公司 一种2-羟基-2,2-二噻吩-2-基乙酸-1-氮杂二环[2,2,2]辛-3(r)-基酯制备方法
KR101511090B1 (ko) 2014-04-24 2015-04-10 고려대학교 산학협력단 염증성 질환의 예방 또는 치료용 약학 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
NO2005012I1 (no) * 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin og farmasoytisk akseptable salter derav
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
KR100869721B1 (ko) * 2000-12-28 2008-11-21 알미랄 에이쥐 신규한 퀴누클리딘 유도체 및 그를 함유한 의약 조성물
EP1438309A1 (en) * 2001-10-17 2004-07-21 Ucb, S.A. Quinuclidine derivatives, processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
ES2204295B1 (es) * 2002-07-02 2005-08-01 Almirall Prodesfarma, S.A. Nuevos derivados de quinuclidina-amida.
AR044134A1 (es) * 2003-05-02 2005-08-24 Novartis Ag Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas.

Also Published As

Publication number Publication date
PE20060005A1 (es) 2006-01-28
DK1725552T3 (da) 2008-10-13
RU2006136085A (ru) 2008-04-27
EP1725552B1 (en) 2008-06-25
ECSP066770A (es) 2006-11-16
TW200604196A (en) 2006-02-01
IL177341A0 (en) 2006-12-10
CA2560157A1 (en) 2005-09-29
ATE399166T1 (de) 2008-07-15
PL1725552T3 (pl) 2008-12-31
RU2382041C2 (ru) 2010-02-20
ES2239546B1 (es) 2006-12-01
CN1930158A (zh) 2007-03-14
KR20070003940A (ko) 2007-01-05
ES2239546A1 (es) 2005-09-16
MY142036A (en) 2010-08-16
JP2007529444A (ja) 2007-10-25
HRP20080338T3 (hr) 2008-07-31
CY1108324T1 (el) 2014-02-12
ES2307168T3 (es) 2008-11-16
AR048004A1 (es) 2006-03-15
SI1725552T1 (sl) 2008-10-31
US20080214600A1 (en) 2008-09-04
WO2005090342A1 (en) 2005-09-29
HK1101855A1 (en) 2007-10-26
AU2005223310A1 (en) 2005-09-29
UA88634C2 (en) 2009-11-10
RS50566B (sr) 2010-05-07
NO20064659L (no) 2006-12-13
DE602005007714D1 (de) 2008-08-07
NZ548583A (en) 2010-05-28
ZA200605931B (en) 2007-11-28
EP1725552A1 (en) 2006-11-29
BRPI0508177A (pt) 2007-08-07

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