UA80258C2 - Methods of treating pulmonary disease - Google Patents
Methods of treating pulmonary disease Download PDFInfo
- Publication number
- UA80258C2 UA80258C2 UA2004042510A UA2004042510A UA80258C2 UA 80258 C2 UA80258 C2 UA 80258C2 UA 2004042510 A UA2004042510 A UA 2004042510A UA 2004042510 A UA2004042510 A UA 2004042510A UA 80258 C2 UA80258 C2 UA 80258C2
- Authority
- UA
- Ukraine
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- group
- pulmonary
- alkyl
- dipropyl
- substituted
- Prior art date
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- 210000002460 smooth muscle Anatomy 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
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- 239000007921 spray Substances 0.000 description 1
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- 239000008174 sterile solution Substances 0.000 description 1
- 208000008467 subacute bacterial endocarditis Diseases 0.000 description 1
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- 239000006228 supernatant Substances 0.000 description 1
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- 239000004094 surface-active agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000006169 tetracyclic group Chemical class 0.000 description 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
- 125000003831 tetrazolyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 description 1
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- 230000001988 toxicity Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31790801P | 2001-09-06 | 2001-09-06 | |
| PCT/US2002/028580 WO2003022284A1 (en) | 2001-09-06 | 2002-09-06 | Methods of treating pulmonary disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA80258C2 true UA80258C2 (en) | 2007-09-10 |
Family
ID=23235775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2004042510A UA80258C2 (en) | 2001-09-06 | 2002-06-09 | Methods of treating pulmonary disease |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20040259889A1 (ja) |
| EP (1) | EP1429775A4 (ja) |
| JP (2) | JP4388373B2 (ja) |
| KR (1) | KR100979738B1 (ja) |
| CN (1) | CN1564688A (ja) |
| AU (1) | AU2002341618B2 (ja) |
| BR (1) | BR0212329A (ja) |
| CA (1) | CA2459533A1 (ja) |
| EA (1) | EA014684B1 (ja) |
| GE (1) | GEP20074132B (ja) |
| HU (1) | HUP0401805A3 (ja) |
| IL (1) | IL160715A0 (ja) |
| IS (1) | IS7163A (ja) |
| MX (1) | MXPA04002135A (ja) |
| NZ (1) | NZ532083A (ja) |
| PL (1) | PL368935A1 (ja) |
| UA (1) | UA80258C2 (ja) |
| WO (1) | WO2003022284A1 (ja) |
| YU (1) | YU20104A (ja) |
| ZA (1) | ZA200401765B (ja) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04012629A (es) * | 2002-06-12 | 2005-10-18 | Biogen Idec Inc | Metodo para el tratamiento de lesion de reperfusion por isquemia por medio de antagonistas receptores de adenosina. |
| US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
| BRPI0409699A (pt) * | 2003-04-25 | 2006-04-18 | Novacardia Inc | métodos de indução do efeito diurético, de indução, manutenção ou restauração do efeito diurético de diurético não modificador de adenosina, de manutenção, restauração ou melhoria da função renal em paciente, de indução de diurese, de prevenção do inìcio de deficiência renal em paciente com sobrecarga de fluidos ou chf, de tratamento de paciente que sofre de chf e de melhoria dos resultados globais da saúde, composição farmacêutica e seus usos |
| US7247639B2 (en) * | 2003-06-06 | 2007-07-24 | Endacea, Inc. | A1 adenosine receptor antagonists |
| KR20080110776A (ko) * | 2006-04-06 | 2008-12-19 | 노바카르디아, 인코포레이션 | 아데노신 ａ₁ 수용체 길항제 및 항경련제의 공동 투여 |
| CN101466383A (zh) * | 2006-06-16 | 2009-06-24 | 美国诺华卡迪亚公司 | 包含低频率投与aa1ra的肾功能延长改善 |
| JP5274455B2 (ja) | 2006-06-23 | 2013-08-28 | インサイト コーポレイション | Ｈｍ７４ａアゴニストとしてのプリノン誘導体 |
| KR20090025261A (ko) | 2006-06-23 | 2009-03-10 | 인사이트 코포레이션 | Ｈｍ７４ａ 아고니스트로서의 퓨리논 유도체 |
| WO2008121882A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Improved methods of administration of adenosine a1 receptor antagonists |
| WO2008121893A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist |
| EP2217233B1 (en) * | 2007-10-26 | 2018-08-08 | New York University School of Medicine | Methods and compositions for treating hepatic diseases |
| US20090228097A1 (en) * | 2008-03-07 | 2009-09-10 | Abbott Cardiovascular Systems Inc. | A1 Adenosine Receptor Antagonist-Coated Implantable Medical Device |
| US20100063071A1 (en) * | 2008-06-13 | 2010-03-11 | Kiesman William F | Therapeutic compositions and related methods of use |
| EA201291274A1 (ru) * | 2010-06-30 | 2013-12-30 | Джилид Сайэнс, Инк. | Применение антагонистов аденозиновых рецепторов aдля лечения легочной гипертензии |
| CN105209447B (zh) * | 2013-03-14 | 2017-11-21 | 百时美施贵宝公司 | 双环[2.2.2]酸gpr120调节剂 |
| AU2019205661B2 (en) | 2018-01-04 | 2022-06-30 | Impetis Biosciences Ltd. | Tricyclic compounds, compositions and medicinal applications thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208240A (en) * | 1991-03-12 | 1993-05-04 | Merrell Dow Pharmaceuticals Inc. | 8-substituted purines as selective adenosine receptor agents |
| TW252044B (ja) * | 1992-08-10 | 1995-07-21 | Boehringer Ingelheim Kg | |
| US5446046A (en) * | 1993-10-28 | 1995-08-29 | University Of Florida Research Foundation | A1 adenosine receptor agonists and antagonists as diuretics |
| US5504090A (en) * | 1994-03-30 | 1996-04-02 | Trustees Of The University Of Pennsylvania | Compositions and methods for the prevention and treatment of ischemia-reperfusion organ injury |
| EP0812844B1 (de) * | 1996-06-07 | 2002-10-23 | Hoechst Aktiengesellschaft | Verwendung von Theophyllinderivaten zur Behandlung und Propylaxe von Schockzuständen, neue Xanthinverbindungen und Verfahren zu deren Herstellung |
| GB9723553D0 (en) * | 1997-11-07 | 1998-01-07 | Duff Gordon W | Prediction of the risk of chronic obstructive airway disease |
| ZA9810766B (en) * | 1997-11-28 | 1999-05-25 | Mochida Pharm Co Ltd | Novel compounds having cgmp-pde inhibitory activity |
| AU2206999A (en) * | 1998-01-09 | 1999-07-26 | Trustees Of The University Of Pennsylvania, The | Compositions and methods for use in ischemia-reperfusion and endotoxin-related tissue injury |
| EP0970696A1 (en) * | 1998-05-05 | 2000-01-12 | Kyowa Hakko Kogyo Co., Ltd. | Combination of loop diuretics with adenosine A1-receptor antagonists |
| SI1230243T1 (sl) * | 1999-11-12 | 2009-08-31 | Biogen Idec Inc | Policikloalkilpurini kot antagonisti adenozinskega receptorja |
| AU784878B2 (en) * | 1999-12-02 | 2006-07-13 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 A2A and A3 receptors and uses thereof |
-
2002
- 2002-06-09 UA UA2004042510A patent/UA80258C2/uk unknown
- 2002-09-06 BR BR0212329-0A patent/BR0212329A/pt not_active IP Right Cessation
- 2002-09-06 YU YU20104A patent/YU20104A/sh unknown
- 2002-09-06 EA EA200400399A patent/EA014684B1/ru not_active IP Right Cessation
- 2002-09-06 PL PL02368935A patent/PL368935A1/xx not_active Application Discontinuation
- 2002-09-06 EP EP02775769A patent/EP1429775A4/en not_active Withdrawn
- 2002-09-06 US US10/488,573 patent/US20040259889A1/en not_active Abandoned
- 2002-09-06 CN CNA028195264A patent/CN1564688A/zh active Pending
- 2002-09-06 IL IL16071502A patent/IL160715A0/xx unknown
- 2002-09-06 AU AU2002341618A patent/AU2002341618B2/en not_active Ceased
- 2002-09-06 MX MXPA04002135A patent/MXPA04002135A/es not_active Application Discontinuation
- 2002-09-06 JP JP2003526413A patent/JP4388373B2/ja not_active Expired - Lifetime
- 2002-09-06 GE GE5528A patent/GEP20074132B/en unknown
- 2002-09-06 CA CA002459533A patent/CA2459533A1/en not_active Abandoned
- 2002-09-06 KR KR1020047003399A patent/KR100979738B1/ko not_active IP Right Cessation
- 2002-09-06 HU HU0401805A patent/HUP0401805A3/hu unknown
- 2002-09-06 WO PCT/US2002/028580 patent/WO2003022284A1/en active IP Right Grant
- 2002-09-06 NZ NZ532083A patent/NZ532083A/en not_active IP Right Cessation
-
2004
- 2004-02-26 IS IS7163A patent/IS7163A/is unknown
- 2004-03-03 ZA ZA200401765A patent/ZA200401765B/en unknown
-
2009
- 2009-06-22 JP JP2009147918A patent/JP2009209156A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IS7163A (is) | 2004-02-26 |
| HUP0401805A2 (hu) | 2004-12-28 |
| JP2005501915A (ja) | 2005-01-20 |
| CN1564688A (zh) | 2005-01-12 |
| KR100979738B1 (ko) | 2010-09-09 |
| GEP20074132B (en) | 2007-06-25 |
| AU2002341618B2 (en) | 2008-06-26 |
| BR0212329A (pt) | 2004-09-21 |
| KR20040040457A (ko) | 2004-05-12 |
| ZA200401765B (en) | 2005-04-05 |
| YU20104A (sh) | 2006-08-17 |
| PL368935A1 (en) | 2005-04-04 |
| JP2009209156A (ja) | 2009-09-17 |
| IL160715A0 (en) | 2004-08-31 |
| JP4388373B2 (ja) | 2009-12-24 |
| EP1429775A1 (en) | 2004-06-23 |
| EP1429775A4 (en) | 2007-04-11 |
| EA200400399A1 (ru) | 2004-08-26 |
| NZ532083A (en) | 2005-10-28 |
| US20040259889A1 (en) | 2004-12-23 |
| HUP0401805A3 (en) | 2007-05-02 |
| CA2459533A1 (en) | 2003-03-20 |
| EA014684B1 (ru) | 2010-12-30 |
| WO2003022284A1 (en) | 2003-03-20 |
| MXPA04002135A (es) | 2005-03-07 |
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