UA77536C2 - Secondary aminoaniline piperidines as mch1 antagonists and their use - Google Patents
Secondary aminoaniline piperidines as mch1 antagonists and their use Download PDFInfo
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- UA77536C2 UA77536C2 UA20041210489A UA20041210489A UA77536C2 UA 77536 C2 UA77536 C2 UA 77536C2 UA 20041210489 A UA20041210489 A UA 20041210489A UA 20041210489 A UA20041210489 A UA 20041210489A UA 77536 C2 UA77536 C2 UA 77536C2
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- heteroaryl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18914502A | 2002-07-03 | 2002-07-03 | |
| PCT/US2003/021391 WO2004005257A1 (en) | 2002-07-03 | 2003-07-03 | Secondary amino anilinic piperidines as mch1 antagonists and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA77536C2 true UA77536C2 (en) | 2006-12-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20041210489A UA77536C2 (en) | 2002-07-03 | 2003-03-07 | Secondary aminoaniline piperidines as mch1 antagonists and their use |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7473698B2 (ja) |
| EP (1) | EP1556351A4 (ja) |
| JP (1) | JP2005532399A (ja) |
| KR (1) | KR20050034710A (ja) |
| CN (1) | CN1319945C (ja) |
| AU (1) | AU2003259098A1 (ja) |
| BR (1) | BR0312257A (ja) |
| CA (1) | CA2485379A1 (ja) |
| EA (1) | EA008826B1 (ja) |
| HK (1) | HK1080471A1 (ja) |
| IL (1) | IL165730A0 (ja) |
| IS (1) | IS7560A (ja) |
| MX (1) | MXPA04012103A (ja) |
| NO (1) | NO20050113L (ja) |
| NZ (1) | NZ536329A (ja) |
| PL (1) | PL373621A1 (ja) |
| UA (1) | UA77536C2 (ja) |
| WO (1) | WO2004005257A1 (ja) |
| ZA (1) | ZA200409425B (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105544B2 (en) | 2001-07-05 | 2006-09-12 | Synaptic Pharmaceutical Corporation | Substituted alkyl amido piperidines |
| US7199135B2 (en) | 2001-07-05 | 2007-04-03 | H. Lundbeck A/S | Substituted alkyl amido piperidines |
| US20050154020A1 (en) * | 2004-01-14 | 2005-07-14 | Synaptic Pharmaceutical Corporation | 4-Aryl piperidines |
| US20050154022A1 (en) * | 2004-01-14 | 2005-07-14 | H. Lundbeck A/S | 4-aryl piperidines |
| WO2006015279A1 (en) * | 2004-07-28 | 2006-02-09 | Neurogen Corporation | Heterocyclic diamine compounds as ligands of the melanin concentrating hormone receptor useful for the treatment of obesity, diabetes, eating and sexual disorders |
| US20060079683A1 (en) * | 2004-10-08 | 2006-04-13 | Marzabadi Mohammad R | Arylthiobenzylpiperidine derivatives |
| US7329656B2 (en) | 2004-10-08 | 2008-02-12 | H. Lundbeck A/S | Arylthiobenzylpiperidine derivatives |
| US7446204B2 (en) | 2004-10-08 | 2008-11-04 | H. Lundbeck A/S | Amino substituted aryloxybenzylpiperidine derivatives |
| US9452980B2 (en) * | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| EP3757102A1 (en) | 2016-03-17 | 2020-12-30 | F. Hoffmann-La Roche AG | 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0223403B1 (en) | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidine derivative, its preparation, and its use as medicament |
| FR2744448B1 (fr) | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperidines derivees d'aryl piperazine, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
| TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| ES2157148B1 (es) * | 1998-11-18 | 2002-03-01 | Faes Fabrica Espanola De Produ | Nuevas piperidinas 4-sustituidas. |
| US6326381B1 (en) * | 1998-12-17 | 2001-12-04 | American Home Products Corporation | Arylpiperidine and aryl-1,2,5,6-tetrahydropyidine amide derivates |
| US20030082623A1 (en) * | 1998-12-31 | 2003-05-01 | Beth Borowsky | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
| EP1246847A2 (en) * | 2000-07-05 | 2002-10-09 | Synaptic Pharmaceutical Corporation | Dna encoding a human melanin concentrating hormone receptor (mch1) and uses thereof |
| JP2004504303A (ja) | 2000-07-05 | 2004-02-12 | シナプティック・ファーマスーティカル・コーポレーション | 選択的メラニン凝集ホルモン−１（ｍｃｈ１）受容体アンタゴニストおよびその使用 |
| JP2005515961A (ja) | 2001-05-22 | 2005-06-02 | ニューロジェン コーポレイション | メラニン凝集ホルモン受容体リガンド：置換１−ベンジル−４−アリールピペラジン類似体 |
| EA005934B1 (ru) | 2001-07-05 | 2005-08-25 | Х. Лундбекк А/С | Замещённые анилиновые пиперидины в качестве селективных антагонистов мсн |
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2003
- 2003-03-07 UA UA20041210489A patent/UA77536C2/uk unknown
- 2003-07-03 MX MXPA04012103A patent/MXPA04012103A/es active IP Right Grant
- 2003-07-03 BR BR0312257-3A patent/BR0312257A/pt not_active IP Right Cessation
- 2003-07-03 PL PL03373621A patent/PL373621A1/xx not_active Application Discontinuation
- 2003-07-03 JP JP2004520047A patent/JP2005532399A/ja not_active Withdrawn
- 2003-07-03 US US10/518,675 patent/US7473698B2/en not_active Expired - Fee Related
- 2003-07-03 NZ NZ536329A patent/NZ536329A/en unknown
- 2003-07-03 CN CNB038157667A patent/CN1319945C/zh not_active Expired - Fee Related
- 2003-07-03 EP EP03763374A patent/EP1556351A4/en not_active Withdrawn
- 2003-07-03 KR KR1020057000078A patent/KR20050034710A/ko not_active Application Discontinuation
- 2003-07-03 IL IL16573003A patent/IL165730A0/xx unknown
- 2003-07-03 AU AU2003259098A patent/AU2003259098A1/en not_active Abandoned
- 2003-07-03 WO PCT/US2003/021391 patent/WO2004005257A1/en active Application Filing
- 2003-07-03 CA CA002485379A patent/CA2485379A1/en not_active Abandoned
- 2003-07-03 EA EA200500152A patent/EA008826B1/ru not_active IP Right Cessation
-
2004
- 2004-11-23 ZA ZA200409425A patent/ZA200409425B/en unknown
- 2004-11-26 IS IS7560A patent/IS7560A/is unknown
-
2005
- 2005-01-10 NO NO20050113A patent/NO20050113L/no not_active Application Discontinuation
-
2006
- 2006-01-09 HK HK06100334A patent/HK1080471A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL165730A0 (en) | 2006-01-15 |
| EA008826B1 (ru) | 2007-08-31 |
| WO2004005257A1 (en) | 2004-01-15 |
| CN1319945C (zh) | 2007-06-06 |
| EP1556351A4 (en) | 2007-07-25 |
| MXPA04012103A (es) | 2005-04-19 |
| US20050245743A1 (en) | 2005-11-03 |
| US7473698B2 (en) | 2009-01-06 |
| EP1556351A1 (en) | 2005-07-27 |
| BR0312257A (pt) | 2005-04-12 |
| EA200500152A1 (ru) | 2005-06-30 |
| NO20050113L (no) | 2005-01-10 |
| IS7560A (is) | 2004-11-26 |
| PL373621A1 (en) | 2005-09-05 |
| CN1665786A (zh) | 2005-09-07 |
| CA2485379A1 (en) | 2004-01-15 |
| KR20050034710A (ko) | 2005-04-14 |
| AU2003259098A1 (en) | 2004-01-23 |
| NZ536329A (en) | 2007-06-29 |
| ZA200409425B (en) | 2006-04-26 |
| JP2005532399A (ja) | 2005-10-27 |
| HK1080471A1 (en) | 2006-04-28 |
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