UA76997C2 - Use of 2-phenyl substituted imidazotriazinones for treating diseases related to cgmp metabolism - Google Patents
Use of 2-phenyl substituted imidazotriazinones for treating diseases related to cgmp metabolism Download PDFInfo
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- UA76997C2 UA76997C2 UA2004021279A UA2004021279A UA76997C2 UA 76997 C2 UA76997 C2 UA 76997C2 UA 2004021279 A UA2004021279 A UA 2004021279A UA 2004021279 A UA2004021279 A UA 2004021279A UA 76997 C2 UA76997 C2 UA 76997C2
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- UA
- Ukraine
- Prior art keywords
- methyl
- propyl
- phenyl
- ethyl
- ethoxy
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10135815A DE10135815A1 (de) | 2001-07-23 | 2001-07-23 | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| PCT/EP2002/007959 WO2003011262A2 (de) | 2001-07-23 | 2002-07-17 | Verwendung von 2-alkoxyphenyl-substituierten imidazotriazinonen zur behandlung von erkrankungen, die im zusammenhang mit cgmp-regulierten vorgängen stehen |
Publications (1)
| Publication Number | Publication Date |
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| UA76997C2 true UA76997C2 (en) | 2006-10-16 |
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| UA2004021279A UA76997C2 (en) | 2001-07-23 | 2002-07-17 | Use of 2-phenyl substituted imidazotriazinones for treating diseases related to cgmp metabolism |
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| EP (2) | EP1733728A3 (ja) |
| JP (1) | JP2005504751A (ja) |
| KR (1) | KR20040032865A (ja) |
| CN (1) | CN1649593A (ja) |
| AT (1) | ATE442144T1 (ja) |
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| BG (1) | BG108533A (ja) |
| BR (1) | BR0211359A (ja) |
| CA (1) | CA2454414A1 (ja) |
| CO (1) | CO5560536A2 (ja) |
| CZ (1) | CZ2004128A3 (ja) |
| DE (2) | DE10135815A1 (ja) |
| EC (1) | ECSP044956A (ja) |
| EE (1) | EE200400056A (ja) |
| ES (1) | ES2330418T3 (ja) |
| HR (1) | HRP20040065A2 (ja) |
| HU (1) | HUP0500734A3 (ja) |
| IL (1) | IL159840A0 (ja) |
| MA (1) | MA26128A1 (ja) |
| MX (1) | MXPA04000675A (ja) |
| NO (1) | NO20040294L (ja) |
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| PL (1) | PL373392A1 (ja) |
| RU (1) | RU2321406C9 (ja) |
| SK (1) | SK442004A3 (ja) |
| UA (1) | UA76997C2 (ja) |
| WO (1) | WO2003011262A2 (ja) |
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| DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| JP2006219374A (ja) * | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Ｐｄｅ７阻害作用を有するイミダゾトリアジノン誘導体 |
| DE102004023069A1 (de) | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
| DE102004038328A1 (de) * | 2004-08-06 | 2006-03-16 | Bayer Healthcare Ag | Neue Verwendungen von 2-Phenyl-substituierten Imidazotriazinon-Derivaten |
| JP2008536888A (ja) | 2005-04-19 | 2008-09-11 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 肺高血圧症の治療のためのロフルミラスト |
| EP2521721B1 (en) | 2009-12-30 | 2014-10-01 | Shanghai Fochon Pharmaceutical Co. Ltd | 3-(3-aminopiperidin-1-yl)-5-oxo-1,2,4-triazine derivates as dipeptidyl peptidase iv(dpp-iv) inhibitors |
| AT512084A1 (de) * | 2011-10-20 | 2013-05-15 | Univ Wien Tech | Diazabicyclo- und diazaspiro-alkanderivate als phosphodiesterase-5 inhibitoren |
| EP3082428A4 (en) | 2013-12-09 | 2017-08-02 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
| EP3554506B1 (en) * | 2016-12-16 | 2021-04-28 | Cystic Fibrosis Foundation | Bycyclic heteroaryl derivatives as cftr potentiators |
| CN113461694A (zh) * | 2021-08-05 | 2021-10-01 | 广东西捷药业有限公司 | 一种伐地那非类似物及其合成方法和应用 |
| CN113583003A (zh) * | 2021-08-05 | 2021-11-02 | 广东西捷药业有限公司 | 一种伐地那非类似物及其合成方法和应用 |
Family Cites Families (39)
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| BE791025A (fr) | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
| GB1457873A (en) | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
| DK109578A (da) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
| US4308384A (en) | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
| US4479210A (en) * | 1982-11-19 | 1984-10-23 | U.S. Philips Corporation | Record-disc player |
| GB9301192D0 (en) * | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
| US6143746A (en) * | 1994-01-21 | 2000-11-07 | Icos Corporation | Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use |
| US5656629A (en) * | 1995-03-10 | 1997-08-12 | Sanofi Winthrop, Inc. | 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof |
| JPH11503445A (ja) * | 1995-04-10 | 1999-03-26 | 藤沢薬品工業株式会社 | ｃＧＭＰ−ＰＤＥ阻害剤としてのインドール誘導体 |
| DE69635135T2 (de) * | 1995-12-28 | 2006-07-06 | Fujisawa Pharmaceutical Co., Ltd. | Benzimidazolderivate |
| CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
| ES2386420T3 (es) * | 1997-11-12 | 2012-08-20 | Bayer Pharma Aktiengesellschaft | Imidazotriazinonas sustituidas con fenilo en la posición 2 como inhibidores de fosfodiesterasas |
| DE19812462A1 (de) * | 1998-03-23 | 1999-09-30 | Bayer Ag | 2-[2-Ethoxy-5(4-ethyl-piperazin-1-sulfonyl) -phenyl]-5-methyl-7-prophyl-3H-imidazo[5,1-f][1,2,4]triazin-4-on Dihydrochlorid |
| ES2212383T3 (es) * | 1997-12-12 | 2004-07-16 | Osi Pharmaceuticals, Inc. | Derivados de n-bencil-3-indenilacetamidas para el tratamiento de neoplasias. |
| US6087368A (en) * | 1998-06-08 | 2000-07-11 | Bristol-Myers Squibb Company | Quinazolinone inhibitors of cGMP phosphodiesterase |
| DE19827640A1 (de) | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
| IL132406A0 (en) * | 1998-10-21 | 2001-03-19 | Pfizer Prod Inc | Treatment of bph with cgmp elevators |
| US6225315B1 (en) * | 1998-11-30 | 2001-05-01 | Pfizer Inc | Method of treating nitrate-induced tolerance |
| FR2792634B1 (fr) * | 1999-04-20 | 2001-06-01 | Synthelabo | Derives de 2-alcoxy-cyclobutene-3,4-dione leur preparation et leur application en therapeutique |
| IL130968A (en) * | 1999-07-15 | 2002-12-01 | Shmuel Simon | Pharmaceutical composition comprising sildenafil or its analogs, useful for the treatment of tinnitus and hearing loss |
| AU775102B2 (en) * | 1999-09-13 | 2004-07-15 | David M. Swope | Composition and method for decreasing neurologic symptomatology |
| DE19943815A1 (de) * | 1999-09-14 | 2001-03-15 | Merck Patent Gmbh | Verwendung von Thienopyrimidinen |
| CA2323008C (en) | 1999-10-11 | 2005-07-12 | Pfizer Inc. | Pharmaceutically active compounds |
| TWI265925B (en) * | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
| EP1220672B1 (de) * | 1999-10-12 | 2006-10-04 | Lilly Icos LLC | Arzneimittel zur behandlung von neuropathien |
| IL139073A0 (en) * | 1999-10-21 | 2001-11-25 | Pfizer | Treatment of neuropathy |
| TW200400821A (en) | 1999-11-02 | 2004-01-16 | Pfizer | Pharmaceutical composition (II) useful for treating or preventing pulmonary hypertension in a patient |
| GB0008694D0 (en) * | 2000-04-07 | 2000-05-31 | Novartis Ag | Organic compounds |
| CA2406947A1 (en) * | 2000-04-19 | 2001-10-25 | Johns Hopkins University | Methods for prevention and treatment of gastrointestinal disorders |
| US20020006926A1 (en) * | 2000-04-19 | 2002-01-17 | Roylance H. H. | Use of cyclic GMP-specific phosphodiesterase inhibitors for treatment of parkinson's disease |
| KR20030023747A (ko) * | 2000-08-11 | 2003-03-19 | 화이자 인코포레이티드 | 인슐린 저항성 증후군의 치료 |
| AU2001286832A1 (en) * | 2000-08-30 | 2002-03-13 | Lilly Icos Llc | Method for treatment of migraine using PDE5 inhibitors |
| GB0025782D0 (en) * | 2000-10-20 | 2000-12-06 | Pfizer Ltd | Use of inhibitors |
| CA2436576A1 (en) * | 2001-02-02 | 2002-08-08 | Pfizer Inc. | Treatment of diabetes mellitus using vardenafil |
| DE10107639A1 (de) * | 2001-02-15 | 2002-08-22 | Bayer Ag | 2-Alkoxyphenyl-substituierte Imidazotriazinone |
| ES2278927T3 (es) * | 2001-05-09 | 2007-08-16 | Bayer Healthcare Ag | Nuevo uso de imidazotriazinonas de 2-(2-etoxi-5-(4-metil-piperazin-1-sulfonil)-fenil)-5-metil-7-propil-3h-imidazo(5,1-f)(1,2,4)triazin-4-ona. |
| DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| GB0129274D0 (en) * | 2001-12-06 | 2002-01-23 | Pfizer Ltd | Novel kit |
| JP2005527510A (ja) * | 2002-03-06 | 2005-09-15 | セレジー ファーマシューティカルズ インコーポレーティッド | 癌の治療において一酸化窒素模倣体を使用するための製剤および方法 |
-
2001
- 2001-07-23 DE DE10135815A patent/DE10135815A1/de not_active Withdrawn
-
2002
- 2002-07-17 US US10/483,462 patent/US6930108B2/en not_active Expired - Fee Related
- 2002-07-17 AT AT02748858T patent/ATE442144T1/de not_active IP Right Cessation
- 2002-07-17 KR KR10-2004-7001050A patent/KR20040032865A/ko not_active Application Discontinuation
- 2002-07-17 CN CNA028144759A patent/CN1649593A/zh active Pending
- 2002-07-17 BR BR0211359-7A patent/BR0211359A/pt not_active IP Right Cessation
- 2002-07-17 CA CA002454414A patent/CA2454414A1/en not_active Abandoned
- 2002-07-17 ES ES02748858T patent/ES2330418T3/es not_active Expired - Lifetime
- 2002-07-17 HU HU0500734A patent/HUP0500734A3/hu unknown
- 2002-07-17 DE DE50213840T patent/DE50213840D1/de not_active Expired - Fee Related
- 2002-07-17 SK SK44-2004A patent/SK442004A3/sk not_active Application Discontinuation
- 2002-07-17 CZ CZ2004128A patent/CZ2004128A3/cs unknown
- 2002-07-17 RU RU2004105265/15A patent/RU2321406C9/ru not_active IP Right Cessation
- 2002-07-17 JP JP2003516493A patent/JP2005504751A/ja active Pending
- 2002-07-17 EP EP06017257A patent/EP1733728A3/de not_active Withdrawn
- 2002-07-17 MX MXPA04000675A patent/MXPA04000675A/es active IP Right Grant
- 2002-07-17 WO PCT/EP2002/007959 patent/WO2003011262A2/de active Application Filing
- 2002-07-17 NZ NZ530703A patent/NZ530703A/en unknown
- 2002-07-17 EE EEP200400056A patent/EE200400056A/xx unknown
- 2002-07-17 IL IL15984002A patent/IL159840A0/xx unknown
- 2002-07-17 EP EP02748858A patent/EP1474150B1/de not_active Expired - Lifetime
- 2002-07-17 UA UA2004021279A patent/UA76997C2/uk unknown
- 2002-07-17 AU AU2002319296A patent/AU2002319296B2/en not_active Ceased
- 2002-07-17 PL PL02373392A patent/PL373392A1/xx not_active Application Discontinuation
-
2004
- 2004-01-14 BG BG108533A patent/BG108533A/bg unknown
- 2004-01-19 EC EC2004004956A patent/ECSP044956A/es unknown
- 2004-01-22 HR HRP20040065 patent/HRP20040065A2/xx not_active Application Discontinuation
- 2004-01-22 MA MA27497A patent/MA26128A1/fr unknown
- 2004-01-22 NO NO20040294A patent/NO20040294L/no not_active Application Discontinuation
- 2004-02-23 CO CO04015666A patent/CO5560536A2/es not_active Application Discontinuation
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2005
- 2005-06-17 US US11/156,082 patent/US7276504B2/en not_active Expired - Fee Related
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2007
- 2007-10-01 US US11/906,382 patent/US20080085897A1/en not_active Abandoned
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