UA41315C2 - Вакцинна композиція проти респіраторно-синцитіального вірусу, спосіб стимулювання імунної системи індивідуума для індукції захисту проти респіраторно-синцитіального вірусу - Google Patents

Вакцинна композиція проти респіраторно-синцитіального вірусу, спосіб стимулювання імунної системи індивідуума для індукції захисту проти респіраторно-синцитіального вірусу

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Publication number
UA41315C2
UA41315C2 UA94105948A UA94105948A UA41315C2 UA 41315 C2 UA41315 C2 UA 41315C2 UA 94105948 A UA94105948 A UA 94105948A UA 94105948 A UA94105948 A UA 94105948A UA 41315 C2 UA41315 C2 UA 41315C2
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Ukraine
Prior art keywords
attenuated
virus
individual
immune system
stimulation
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UA94105948A
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English (en)
Inventor
Брайєн Роберт Мьорфі
Роберт Мєрріт Ченок
Джеймс Ерл Крауе
Марк КОННОРС
Куо-хом Лі Хсу
Алан Роберт Девіс
Майкл Девід Любек
Бернард Х'ю Селлінг
Original Assignee
Амерікан Хоум Продактс Корпорейшн
Американ Хоум Продактс Корпорейшн
Сполучені Штати Америки, Що Представлені Департаментом Охорони Здоров'Я
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Application filed by Амерікан Хоум Продактс Корпорейшн, Американ Хоум Продактс Корпорейшн, Сполучені Штати Америки, Що Представлені Департаментом Охорони Здоров'Я filed Critical Амерікан Хоум Продактс Корпорейшн
Publication of UA41315C2 publication Critical patent/UA41315C2/uk

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18561Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Vertical, Hearth, Or Arc Furnaces (AREA)

Abstract

Даний винахід стосується металургії. Пропонується конструкція шахти доменної печі, що містить кожух, який у охолоджуваній частині шахти захищений вогнетривкою футерівкою, а у не охолоджуваній частині шахти футерований металевими не охолоджуваними плитами. Обернений до середини печі бік плит має заглиблення, заповнені вогнетривким матеріалом. Така конструкція шахти дає можливість зберегти профіль доменної печі протягом кампанії, заощадити вогнетривкі матеріали та запобігти продувам кожуху у не охолоджуваній частині шахти.
UA94105948A 1992-04-21 1993-04-20 Вакцинна композиція проти респіраторно-синцитіального вірусу, спосіб стимулювання імунної системи індивідуума для індукції захисту проти респіраторно-синцитіального вірусу UA41315C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87274692A 1992-04-21 1992-04-21
US3994593A 1993-04-09 1993-04-09
PCT/US1993/003670 WO1993021310A1 (en) 1992-04-21 1993-04-20 Attenuated respiratory syncytial virus vaccine compositions

Publications (1)

Publication Number Publication Date
UA41315C2 true UA41315C2 (uk) 2001-09-17

Family

ID=26716607

Family Applications (1)

Application Number Title Priority Date Filing Date
UA94105948A UA41315C2 (uk) 1992-04-21 1993-04-20 Вакцинна композиція проти респіраторно-синцитіального вірусу, спосіб стимулювання імунної системи індивідуума для індукції захисту проти респіраторно-синцитіального вірусу

Country Status (18)

Country Link
US (3) US5922326A (uk)
EP (1) EP0640128B1 (uk)
JP (1) JP3883202B2 (uk)
KR (1) KR100257171B1 (uk)
AT (1) ATE181359T1 (uk)
AU (1) AU683840B2 (uk)
CA (1) CA2118509C (uk)
DE (1) DE69325370T2 (uk)
DK (1) DK0640128T3 (uk)
ES (1) ES2132233T3 (uk)
GR (1) GR3031208T3 (uk)
HU (1) HU220189B (uk)
IL (1) IL105456A (uk)
MX (1) MX9302278A (uk)
NZ (1) NZ252857A (uk)
RU (1) RU2139729C1 (uk)
UA (1) UA41315C2 (uk)
WO (1) WO1993021310A1 (uk)

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Also Published As

Publication number Publication date
JPH07505891A (ja) 1995-06-29
KR100257171B1 (ko) 2000-05-15
EP0640128B1 (en) 1999-06-16
RU2139729C1 (ru) 1999-10-20
CA2118509A1 (en) 1993-10-28
AU4290793A (en) 1993-11-18
US5882651A (en) 1999-03-16
MX9302278A (es) 1994-07-29
HUT69992A (en) 1995-09-28
KR950701382A (ko) 1995-03-23
US5922326A (en) 1999-07-13
EP0640128A1 (en) 1995-03-01
DE69325370T2 (de) 1999-10-14
DK0640128T3 (da) 1999-11-22
WO1993021310A1 (en) 1993-10-28
IL105456A0 (en) 1993-08-18
ATE181359T1 (de) 1999-07-15
DE69325370D1 (de) 1999-07-22
NZ252857A (en) 1997-06-24
GR3031208T3 (en) 1999-12-31
HU220189B (hu) 2001-11-28
IL105456A (en) 1996-12-05
US6284254B1 (en) 2001-09-04
HU9403023D0 (en) 1994-12-28
RU94045898A (ru) 1996-09-20
ES2132233T3 (es) 1999-08-16
JP3883202B2 (ja) 2007-02-21
AU683840B2 (en) 1997-11-27
CA2118509C (en) 2009-05-19

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