UA115141C2 - Водний офтальмологічний розчин на основі циклоспорину a - Google Patents

Водний офтальмологічний розчин на основі циклоспорину a

Info

Publication number
UA115141C2
UA115141C2 UAA201409442A UAA201409442A UA115141C2 UA 115141 C2 UA115141 C2 UA 115141C2 UA A201409442 A UAA201409442 A UA A201409442A UA A201409442 A UAA201409442 A UA A201409442A UA 115141 C2 UA115141 C2 UA 115141C2
Authority
UA
Ukraine
Prior art keywords
cyclosporin
ophthalmic solution
aqueous ophthalmic
based aqueous
relates
Prior art date
Application number
UAA201409442A
Other languages
English (en)
Inventor
Еммануель Мюрьо
Фабріс Мерсьє
Original Assignee
Лаборатуар Теа
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46298539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA115141(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Лаборатуар Теа filed Critical Лаборатуар Теа
Publication of UA115141C2 publication Critical patent/UA115141C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Винахід стосується водного офтальмологічного розчину, що містить як імуносупресивний засіб циклоспорин А, як перший полімер похідну целюлози, як другий полімер похідну полівінілу та полімер з ліпофільною функціональною групою як третій полімер.
UAA201409442A 2012-03-22 2013-03-15 Водний офтальмологічний розчин на основі циклоспорину a UA115141C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261614218P 2012-03-22 2012-03-22
FR1252583A FR2988297B1 (fr) 2012-03-22 2012-03-22 Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
PCT/FR2013/050557 WO2013140071A1 (fr) 2012-03-22 2013-03-15 Solution ophtalmique aqueuse a base de ciclosporine a

Publications (1)

Publication Number Publication Date
UA115141C2 true UA115141C2 (uk) 2017-09-25

Family

ID=46298539

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201409442A UA115141C2 (uk) 2012-03-22 2013-03-15 Водний офтальмологічний розчин на основі циклоспорину a

Country Status (23)

Country Link
US (1) US8969305B2 (uk)
EP (1) EP2827840B1 (uk)
JP (1) JP6166341B2 (uk)
KR (1) KR102021633B1 (uk)
AR (1) AR090466A1 (uk)
BR (1) BR112014019141A8 (uk)
CA (1) CA2863000C (uk)
CL (1) CL2014002271A1 (uk)
CY (1) CY1122086T1 (uk)
DK (1) DK2827840T3 (uk)
ES (1) ES2746701T3 (uk)
FR (1) FR2988297B1 (uk)
HU (1) HUE045252T2 (uk)
LT (1) LT2827840T (uk)
MA (1) MA37297B1 (uk)
MX (1) MX350799B (uk)
PL (1) PL2827840T3 (uk)
PT (1) PT2827840T (uk)
RS (1) RS59324B1 (uk)
RU (1) RU2634267C2 (uk)
SI (1) SI2827840T1 (uk)
UA (1) UA115141C2 (uk)
WO (1) WO2013140071A1 (uk)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015093924A1 (es) * 2013-12-19 2015-06-25 CASTRO ALDRETE, Jorge Issac Vehículo para la administración de compuestos farmacéuticos

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0558906A (ja) * 1991-09-06 1993-03-09 Sankyo Co Ltd シクロスポリン点眼製剤
WO1993023010A1 (en) * 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
US6254860B1 (en) 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
ES2206363T3 (es) 2000-04-07 2004-05-16 Laboratoire Medidom S.A. Formulaciones oftalmicas a base de ciclosporina, de acido hialuronico y de polisorbato.
CN1127955C (zh) * 2000-07-07 2003-11-19 中山医科大学中山眼科中心 一种眼前段及眼表免疫相关性疾病治疗药物
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
WO2006073786A2 (en) * 2004-12-30 2006-07-13 Bausch & Lomb Incorporated Ophthalmic compositions comprising steroid and cyclosporine for dry eye therapy
US9561178B2 (en) * 2006-07-25 2017-02-07 Allergan, Inc. Cyclosporin compositions
US20080146497A1 (en) * 2006-07-25 2008-06-19 Graham Richard S Cyclosporin Compositions
JP5668476B2 (ja) * 2007-10-08 2015-02-12 オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物
CA2702082A1 (en) * 2007-10-08 2009-04-16 Fovea Pharmaceuticals Sa Aqueous ophthalmic formulations
WO2009058585A2 (en) * 2007-11-01 2009-05-07 Bausch & Lomb Incorporated Non-aqueous water-miscible materials as vehicles for drug delivery
US20090286718A1 (en) * 2008-01-04 2009-11-19 Sirion Therapeutics, Inc. Stable Aqueous Cyclosporin Compositions
CN101244035A (zh) * 2008-02-21 2008-08-20 南京医科大学附属南京第一医院 一种环孢菌素a眼用乳剂制剂及其制备方法
KR20120022574A (ko) * 2010-07-30 2012-03-12 주식회사종근당 사이클로스포린 에이 함유 점안제 조성물

Also Published As

Publication number Publication date
EP2827840B1 (fr) 2019-08-28
HUE045252T2 (hu) 2019-12-30
ES2746701T3 (es) 2020-03-06
MA37297B1 (fr) 2017-01-31
US20130267472A1 (en) 2013-10-10
RS59324B1 (sr) 2019-10-31
MX350799B (es) 2017-09-25
CY1122086T1 (el) 2020-11-25
DK2827840T3 (da) 2019-09-30
SI2827840T1 (sl) 2019-11-29
WO2013140071A1 (fr) 2013-09-26
KR20140136932A (ko) 2014-12-01
RU2014134741A (ru) 2016-03-20
LT2827840T (lt) 2019-10-10
PT2827840T (pt) 2019-10-11
BR112014019141A8 (pt) 2017-07-11
CL2014002271A1 (es) 2014-11-03
AR090466A1 (es) 2014-11-12
MX2014010270A (es) 2015-01-14
MA37297A1 (fr) 2016-05-31
EP2827840A1 (fr) 2015-01-28
JP6166341B2 (ja) 2017-07-19
JP2015510921A (ja) 2015-04-13
CA2863000A1 (fr) 2013-09-26
CA2863000C (fr) 2020-04-21
KR102021633B1 (ko) 2019-09-16
FR2988297B1 (fr) 2014-03-28
US8969305B2 (en) 2015-03-03
BR112014019141A2 (uk) 2017-06-20
FR2988297A1 (fr) 2013-09-27
PL2827840T3 (pl) 2019-12-31
RU2634267C2 (ru) 2017-10-24

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