BR112014019141A8 - Solução oftálmica aquosa, frasco de uso único ou multidose produzido em pebd e processo de preparação - Google Patents

Solução oftálmica aquosa, frasco de uso único ou multidose produzido em pebd e processo de preparação

Info

Publication number
BR112014019141A8
BR112014019141A8 BR112014019141A BR112014019141A BR112014019141A8 BR 112014019141 A8 BR112014019141 A8 BR 112014019141A8 BR 112014019141 A BR112014019141 A BR 112014019141A BR 112014019141 A BR112014019141 A BR 112014019141A BR 112014019141 A8 BR112014019141 A8 BR 112014019141A8
Authority
BR
Brazil
Prior art keywords
ophthalmic solution
ldpe
aqueous ophthalmic
preparation process
multidose vial
Prior art date
Application number
BR112014019141A
Other languages
English (en)
Other versions
BR112014019141A2 (pt
Inventor
Muriaux Emmanuel
Mercier Fabrice
Original Assignee
Thea Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46298539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014019141(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thea Lab filed Critical Thea Lab
Publication of BR112014019141A2 publication Critical patent/BR112014019141A2/pt
Publication of BR112014019141A8 publication Critical patent/BR112014019141A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SOLUÇÃO OFTÁLMICA AQUOSA, FRASCO DE USO ÚNICO OU MULTIDOSE PRODUZIDO EM PEBD E PROCESSO DE PREPARAÇÃO. Esta invenção diz respeito a uma solução oftálmica aquosa que contém um agente imunossupressor, tal como a ciclosporina A, e pelo menos três polímeros. É preferencialmente uma combinação de um derivado de celulose, um derivado de polivinila, e um hidroxiestearato de macrogolglicerol.
BR112014019141A 2012-03-22 2013-03-15 Solução oftálmica aquosa, frasco de uso único ou multidose produzido em pebd e processo de preparação BR112014019141A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261614218P 2012-03-22 2012-03-22
FR1252583A FR2988297B1 (fr) 2012-03-22 2012-03-22 Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
PCT/FR2013/050557 WO2013140071A1 (fr) 2012-03-22 2013-03-15 Solution ophtalmique aqueuse a base de ciclosporine a

Publications (2)

Publication Number Publication Date
BR112014019141A2 BR112014019141A2 (pt) 2017-06-20
BR112014019141A8 true BR112014019141A8 (pt) 2017-07-11

Family

ID=46298539

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014019141A BR112014019141A8 (pt) 2012-03-22 2013-03-15 Solução oftálmica aquosa, frasco de uso único ou multidose produzido em pebd e processo de preparação

Country Status (23)

Country Link
US (1) US8969305B2 (pt)
EP (1) EP2827840B1 (pt)
JP (1) JP6166341B2 (pt)
KR (1) KR102021633B1 (pt)
AR (1) AR090466A1 (pt)
BR (1) BR112014019141A8 (pt)
CA (1) CA2863000C (pt)
CL (1) CL2014002271A1 (pt)
CY (1) CY1122086T1 (pt)
DK (1) DK2827840T3 (pt)
ES (1) ES2746701T3 (pt)
FR (1) FR2988297B1 (pt)
HU (1) HUE045252T2 (pt)
LT (1) LT2827840T (pt)
MA (1) MA37297B1 (pt)
MX (1) MX350799B (pt)
PL (1) PL2827840T3 (pt)
PT (1) PT2827840T (pt)
RS (1) RS59324B1 (pt)
RU (1) RU2634267C2 (pt)
SI (1) SI2827840T1 (pt)
UA (1) UA115141C2 (pt)
WO (1) WO2013140071A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015093924A1 (es) * 2013-12-19 2015-06-25 CASTRO ALDRETE, Jorge Issac Vehículo para la administración de compuestos farmacéuticos

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0558906A (ja) * 1991-09-06 1993-03-09 Sankyo Co Ltd シクロスポリン点眼製剤
JP3631490B2 (ja) * 1992-05-13 2005-03-23 ノバルティス ファーマ株式会社 シクロスポリン含有眼科用組成物
US6254860B1 (en) 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DK1142566T3 (da) 2000-04-07 2004-02-09 Medidom Lab Oftalmologiske formuleringer på basis af ciclosporin, hyaluronsyre og polysorbat
CN1127955C (zh) * 2000-07-07 2003-11-19 中山医科大学中山眼科中心 一种眼前段及眼表免疫相关性疾病治疗药物
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US20060148686A1 (en) * 2004-12-30 2006-07-06 Bausch & Lomb Incorporated Ophthalmic compositions comprising steroid and cyclosporine for dry eye therapy
US9561178B2 (en) * 2006-07-25 2017-02-07 Allergan, Inc. Cyclosporin compositions
US20080146497A1 (en) * 2006-07-25 2008-06-19 Graham Richard S Cyclosporin Compositions
AU2008310956B2 (en) * 2007-10-08 2014-08-07 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors
NZ584275A (en) * 2007-10-08 2012-06-29 Fovea Pharmaceuticals Aqueous cyclosporine ophthalmic formulations
CN101842080A (zh) * 2007-11-01 2010-09-22 博士伦公司 非水的水混溶性物质作为药物递送的载体
BRPI0822221A2 (pt) * 2008-01-04 2015-06-23 Alcon Pharmaceuticals Ltd Composições aquosas e estáveis de ciclosporina
CN101244035A (zh) * 2008-02-21 2008-08-20 南京医科大学附属南京第一医院 一种环孢菌素a眼用乳剂制剂及其制备方法
KR20120022574A (ko) * 2010-07-30 2012-03-12 주식회사종근당 사이클로스포린 에이 함유 점안제 조성물

Also Published As

Publication number Publication date
PL2827840T3 (pl) 2019-12-31
FR2988297A1 (fr) 2013-09-27
RU2014134741A (ru) 2016-03-20
RS59324B1 (sr) 2019-10-31
JP2015510921A (ja) 2015-04-13
MX2014010270A (es) 2015-01-14
KR20140136932A (ko) 2014-12-01
CA2863000A1 (fr) 2013-09-26
CA2863000C (fr) 2020-04-21
PT2827840T (pt) 2019-10-11
BR112014019141A2 (pt) 2017-06-20
JP6166341B2 (ja) 2017-07-19
EP2827840A1 (fr) 2015-01-28
ES2746701T3 (es) 2020-03-06
UA115141C2 (uk) 2017-09-25
HUE045252T2 (hu) 2019-12-30
MX350799B (es) 2017-09-25
CL2014002271A1 (es) 2014-11-03
KR102021633B1 (ko) 2019-09-16
CY1122086T1 (el) 2020-11-25
MA37297A1 (fr) 2016-05-31
MA37297B1 (fr) 2017-01-31
US20130267472A1 (en) 2013-10-10
WO2013140071A1 (fr) 2013-09-26
SI2827840T1 (sl) 2019-11-29
DK2827840T3 (da) 2019-09-30
LT2827840T (lt) 2019-10-10
RU2634267C2 (ru) 2017-10-24
AR090466A1 (es) 2014-11-12
US8969305B2 (en) 2015-03-03
EP2827840B1 (fr) 2019-08-28
FR2988297B1 (fr) 2014-03-28

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]