CY1122086T1 - Ενυδατικο οφθαλμικο διαλυμα με βαση την κυκλοσπορινη α - Google Patents

Ενυδατικο οφθαλμικο διαλυμα με βαση την κυκλοσπορινη α

Info

Publication number
CY1122086T1
CY1122086T1 CY20191101012T CY191101012T CY1122086T1 CY 1122086 T1 CY1122086 T1 CY 1122086T1 CY 20191101012 T CY20191101012 T CY 20191101012T CY 191101012 T CY191101012 T CY 191101012T CY 1122086 T1 CY1122086 T1 CY 1122086T1
Authority
CY
Cyprus
Prior art keywords
cyclosporin
eye solution
moisturizing eye
moisturizing
relates
Prior art date
Application number
CY20191101012T
Other languages
English (en)
Inventor
Emmanuel MURIAUX
Fabrice Mercier
Original Assignee
Laboratoires Thea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46298539&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1122086(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratoires Thea filed Critical Laboratoires Thea
Publication of CY1122086T1 publication Critical patent/CY1122086T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα ευρεσιτεχνία αφορά σε ένα ενυδατικό οφθαλμικό διάλυμα που περιλαμβάνει ένα ανοσοκατασταλτικό παράγοντα, όπως η κυκλοσπορίνη Α και τουλάχιστον τρία πολυμερή. Η ευρεσιτεχνία πλεονεκτικά αφορά στο συνδυασμό ενός παραγώγου κυτταρίνης, ενός παραγώγου πολυβινυλίου και μιας υδροξυστεατικής μακρογολογλυκερόλης.
CY20191101012T 2012-03-22 2019-09-26 Ενυδατικο οφθαλμικο διαλυμα με βαση την κυκλοσπορινη α CY1122086T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261614218P 2012-03-22 2012-03-22
FR1252583A FR2988297B1 (fr) 2012-03-22 2012-03-22 Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
PCT/FR2013/050557 WO2013140071A1 (fr) 2012-03-22 2013-03-15 Solution ophtalmique aqueuse a base de ciclosporine a

Publications (1)

Publication Number Publication Date
CY1122086T1 true CY1122086T1 (el) 2020-11-25

Family

ID=46298539

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191101012T CY1122086T1 (el) 2012-03-22 2019-09-26 Ενυδατικο οφθαλμικο διαλυμα με βαση την κυκλοσπορινη α

Country Status (23)

Country Link
US (1) US8969305B2 (el)
EP (1) EP2827840B1 (el)
JP (1) JP6166341B2 (el)
KR (1) KR102021633B1 (el)
AR (1) AR090466A1 (el)
BR (1) BR112014019141A8 (el)
CA (1) CA2863000C (el)
CL (1) CL2014002271A1 (el)
CY (1) CY1122086T1 (el)
DK (1) DK2827840T3 (el)
ES (1) ES2746701T3 (el)
FR (1) FR2988297B1 (el)
HU (1) HUE045252T2 (el)
LT (1) LT2827840T (el)
MA (1) MA37297B1 (el)
MX (1) MX350799B (el)
PL (1) PL2827840T3 (el)
PT (1) PT2827840T (el)
RS (1) RS59324B1 (el)
RU (1) RU2634267C2 (el)
SI (1) SI2827840T1 (el)
UA (1) UA115141C2 (el)
WO (1) WO2013140071A1 (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015093924A1 (es) * 2013-12-19 2015-06-25 CASTRO ALDRETE, Jorge Issac Vehículo para la administración de compuestos farmacéuticos

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0558906A (ja) * 1991-09-06 1993-03-09 Sankyo Co Ltd シクロスポリン点眼製剤
WO1993023010A1 (en) * 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
US6254860B1 (en) * 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DE60100866T2 (de) 2000-04-07 2004-07-29 Laboratoire Medidom S.A. Cyklosporin, Hyaluronsäure und Polysorbate enthaltenes Augenarzneimittel
CN1127955C (zh) * 2000-07-07 2003-11-19 中山医科大学中山眼科中心 一种眼前段及眼表免疫相关性疾病治疗药物
TWI336257B (en) * 2003-06-13 2011-01-21 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US20060148686A1 (en) * 2004-12-30 2006-07-06 Bausch & Lomb Incorporated Ophthalmic compositions comprising steroid and cyclosporine for dry eye therapy
US9561178B2 (en) * 2006-07-25 2017-02-07 Allergan, Inc. Cyclosporin compositions
US20080146497A1 (en) * 2006-07-25 2008-06-19 Graham Richard S Cyclosporin Compositions
US20120028910A1 (en) * 2007-10-08 2012-02-02 Jean-Philippe Combal Storage-stable aqueous ophthalmic formulations
CA3014633C (en) * 2007-10-08 2022-05-17 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
CA2702761A1 (en) * 2007-11-01 2009-05-07 Bausch & Lomb Incorporated Non-aqueous water-miscible materials as vehicles for drug delivery
WO2009088570A1 (en) * 2008-01-04 2009-07-16 Sirion Therapeutics, Inc. Stable aqueous cyclosporin compositions
CN101244035A (zh) * 2008-02-21 2008-08-20 南京医科大学附属南京第一医院 一种环孢菌素a眼用乳剂制剂及其制备方法
KR20120022574A (ko) * 2010-07-30 2012-03-12 주식회사종근당 사이클로스포린 에이 함유 점안제 조성물

Also Published As

Publication number Publication date
JP6166341B2 (ja) 2017-07-19
RS59324B1 (sr) 2019-10-31
LT2827840T (lt) 2019-10-10
AR090466A1 (es) 2014-11-12
ES2746701T3 (es) 2020-03-06
CA2863000C (fr) 2020-04-21
RU2634267C2 (ru) 2017-10-24
MA37297A1 (fr) 2016-05-31
KR20140136932A (ko) 2014-12-01
RU2014134741A (ru) 2016-03-20
CA2863000A1 (fr) 2013-09-26
US8969305B2 (en) 2015-03-03
MX2014010270A (es) 2015-01-14
PT2827840T (pt) 2019-10-11
PL2827840T3 (pl) 2019-12-31
UA115141C2 (uk) 2017-09-25
KR102021633B1 (ko) 2019-09-16
EP2827840A1 (fr) 2015-01-28
FR2988297B1 (fr) 2014-03-28
BR112014019141A2 (el) 2017-06-20
BR112014019141A8 (pt) 2017-07-11
MX350799B (es) 2017-09-25
EP2827840B1 (fr) 2019-08-28
HUE045252T2 (hu) 2019-12-30
WO2013140071A1 (fr) 2013-09-26
CL2014002271A1 (es) 2014-11-03
SI2827840T1 (sl) 2019-11-29
FR2988297A1 (fr) 2013-09-27
JP2015510921A (ja) 2015-04-13
DK2827840T3 (da) 2019-09-30
MA37297B1 (fr) 2017-01-31
US20130267472A1 (en) 2013-10-10

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