MX2016002186A - Proceso para preparar dronedarona y sales de la misma. - Google Patents

Proceso para preparar dronedarona y sales de la misma.

Info

Publication number
MX2016002186A
MX2016002186A MX2016002186A MX2016002186A MX2016002186A MX 2016002186 A MX2016002186 A MX 2016002186A MX 2016002186 A MX2016002186 A MX 2016002186A MX 2016002186 A MX2016002186 A MX 2016002186A MX 2016002186 A MX2016002186 A MX 2016002186A
Authority
MX
Mexico
Prior art keywords
salts
preparing dronedarone
dronedarone
preparing
processes
Prior art date
Application number
MX2016002186A
Other languages
English (en)
Inventor
Justin Vitale
Johann Chan
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of MX2016002186A publication Critical patent/MX2016002186A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Materials Engineering (AREA)
  • Furan Compounds (AREA)
  • Epidemiology (AREA)

Abstract

La presente descripción se refiere a procesos para preparar dronedarona o sales farmacéuticamente aceptables de la misma.
MX2016002186A 2013-08-27 2014-08-26 Proceso para preparar dronedarona y sales de la misma. MX2016002186A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361870632P 2013-08-27 2013-08-27
US201361903285P 2013-11-12 2013-11-12
PCT/US2014/052692 WO2015031352A1 (en) 2013-08-27 2014-08-26 Process for preparing dronedarone and salts thereof

Publications (1)

Publication Number Publication Date
MX2016002186A true MX2016002186A (es) 2016-06-06

Family

ID=51492497

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016002186A MX2016002186A (es) 2013-08-27 2014-08-26 Proceso para preparar dronedarona y sales de la misma.

Country Status (15)

Country Link
US (1) US9242953B2 (es)
EP (1) EP3039016B1 (es)
JP (1) JP2016534120A (es)
KR (1) KR20160045880A (es)
CN (1) CN105452232A (es)
AU (1) AU2014311399B2 (es)
CA (1) CA2921201A1 (es)
EA (1) EA201690229A1 (es)
HK (2) HK1219949A1 (es)
IL (1) IL243886A0 (es)
MX (1) MX2016002186A (es)
SG (1) SG11201600763TA (es)
TW (1) TW201536763A (es)
UY (1) UY35715A (es)
WO (1) WO2015031352A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114456135B (zh) * 2022-03-18 2024-09-10 江苏慧聚药业股份有限公司 决奈达隆的制备

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
FR2817864B1 (fr) * 2000-12-11 2003-02-21 Sanofi Synthelabo Derive de methanesulfonamido-benzofurane, son procede de preparation et son utilisation comme intermediaire de synthese
US8108698B2 (en) * 2008-06-04 2012-01-31 Broadcom Corporation Computer storage components that provide external and internal access
CN102753018A (zh) * 2010-02-10 2012-10-24 Mapi医药公司 苯并呋喃的制备及其作为合成中间体的用途
FR2957079B1 (fr) * 2010-03-02 2012-07-27 Sanofi Aventis Procede de synthese de derives de cetobenzofurane
FR2958289B1 (fr) * 2010-03-30 2012-06-15 Sanofi Aventis Procede de preparation de derives de 3-ceto-benzofurane
HUP1000330A2 (en) * 2010-06-18 2011-12-28 Sanofi Sa Process for the preparation of dronedarone and the novel intermediates
HUP1000386A2 (en) * 2010-07-22 2012-05-29 Sanofi Sa Novel process for producing dronedarone
FR2973027A1 (fr) 2011-03-24 2012-09-28 Sanofi Aventis Procede de synthese de derives de cetobenzofurane
WO2013014480A1 (en) 2011-07-26 2013-01-31 Sanofi Process for preparation of dronedarone using amide intermediary compound
EP2617718A1 (en) * 2012-01-20 2013-07-24 Sanofi Process for preparation of dronedarone by the use of dibutylaminopropanol reagent

Also Published As

Publication number Publication date
HK1217194A1 (zh) 2016-12-30
EP3039016A1 (en) 2016-07-06
EP3039016B1 (en) 2017-08-02
EA201690229A1 (ru) 2016-07-29
IL243886A0 (en) 2016-04-21
US20150065734A1 (en) 2015-03-05
US9242953B2 (en) 2016-01-26
HK1219949A1 (zh) 2017-04-21
WO2015031352A1 (en) 2015-03-05
JP2016534120A (ja) 2016-11-04
CN105452232A (zh) 2016-03-30
SG11201600763TA (en) 2016-02-26
AU2014311399A1 (en) 2016-02-25
CA2921201A1 (en) 2015-03-05
KR20160045880A (ko) 2016-04-27
UY35715A (es) 2015-02-27
AU2014311399B2 (en) 2017-06-15
TW201536763A (zh) 2015-10-01

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