UA112297C2 - Рекомбінантна мікобактерія як вакцина для застосування на людях - Google Patents
Рекомбінантна мікобактерія як вакцина для застосування на людяхInfo
- Publication number
- UA112297C2 UA112297C2 UAA201303087A UAA201303087A UA112297C2 UA 112297 C2 UA112297 C2 UA 112297C2 UA A201303087 A UAA201303087 A UA A201303087A UA A201303087 A UAA201303087 A UA A201303087A UA 112297 C2 UA112297 C2 UA 112297C2
- Authority
- UA
- Ukraine
- Prior art keywords
- recombinant
- mycobacterium
- humans
- nucleotides
- seq
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Винахід стосується вакцини проти туберкульозу для застосування на людях, що містить як активний інгредієнт рекомбінантну клітину бактерій Mycobacterium, яка є уреаза-дефіцитною і яка містить молекулу рекомбінантної нуклеїнової кислоти, що кодує гібридний поліпептид, який містить (а) антиген бактерій Mycobacterium, який містить пептидну послідовність, яка кодується нуклеотидами 121-153 послідовності SEQ ID NO: 1, причому цим антигеном бактерій Mycobacterium є Ag85B, або його імуногенний фрагмент, і (b) домен виходу з фаголізосоми, який містить пептидну послідовність, яка кодується нуклеотидами 211-1722 послідовності SEQ ID NO: 1, причому рекомбінантна клітина бактерій Mycobacterium являє собою рекомбінантну клітину бактерій Mycobacterium bovis датського штаму підтипу Prague, яка не несе гена стійкості до антибіотиків.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38437510P | 2010-09-20 | 2010-09-20 | |
| PCT/EP2011/066131 WO2012038348A1 (en) | 2010-09-20 | 2011-09-16 | Recombinant mycobacterium as vaccine for use in humans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA112297C2 true UA112297C2 (uk) | 2016-08-25 |
Family
ID=44645725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201303087A UA112297C2 (uk) | 2010-09-20 | 2011-09-16 | Рекомбінантна мікобактерія як вакцина для застосування на людях |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9084749B2 (uk) |
| EP (2) | EP3360569B1 (uk) |
| JP (1) | JP5919276B2 (uk) |
| KR (1) | KR101907222B1 (uk) |
| CN (1) | CN103118703A (uk) |
| AU (1) | AU2011304385B2 (uk) |
| BR (1) | BR112013006245A2 (uk) |
| CA (1) | CA2811158C (uk) |
| CU (1) | CU24182B1 (uk) |
| CY (2) | CY1120748T1 (uk) |
| DK (2) | DK2618837T3 (uk) |
| EA (1) | EA026661B1 (uk) |
| ES (2) | ES2685928T3 (uk) |
| HK (1) | HK1258603A1 (uk) |
| HR (2) | HRP20181387T1 (uk) |
| HU (2) | HUE039038T2 (uk) |
| LT (2) | LT3360569T (uk) |
| MX (1) | MX346708B (uk) |
| PL (2) | PL2618837T3 (uk) |
| PT (2) | PT3360569T (uk) |
| RS (2) | RS60146B1 (uk) |
| SG (1) | SG188595A1 (uk) |
| SI (2) | SI2618837T1 (uk) |
| UA (1) | UA112297C2 (uk) |
| WO (1) | WO2012038348A1 (uk) |
| ZA (1) | ZA201301187B (uk) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2654783T3 (pl) | 2010-12-21 | 2017-08-31 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Rekombinowane Mycobacterium jako szczepionka |
| EP3090757A1 (en) | 2015-05-04 | 2016-11-09 | Vakzine Projekt Management GmbH | Recombinant mycobacterium as an immunotherapeutic agent for the treatment of cancer |
| KR102338845B1 (ko) | 2020-05-22 | 2021-12-13 | 서울대학교산학협력단 | 플랩 구동 장치 및 회전익기의 블레이드 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5733151A (en) | 1996-08-23 | 1998-03-31 | Edsall; David | Electrical clamping connection device |
| AUPO761697A0 (en) | 1997-06-30 | 1997-07-24 | Cardiac Crc Nominees Pty Limited | Process for the purification of polyethers |
| EP0902086A1 (en) * | 1997-08-22 | 1999-03-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tuberculosis vaccine |
| CN1513551A (zh) * | 2002-09-09 | 2004-07-21 | 丛繁滋 | 复合生物制品组合物及其制备方法 |
| ATE473238T1 (de) | 2003-04-23 | 2010-07-15 | Max Planck Gesellschaft | Tuberkulose vaccine mit verbesserter effizienz |
| EP1649869A1 (en) | 2004-10-21 | 2006-04-26 | Vakzine Projekt Management GmbH | Combination of a recombinant mycobacterium and a biologically active agent as a vaccine |
-
2011
- 2011-09-16 AU AU2011304385A patent/AU2011304385B2/en active Active
- 2011-09-16 CU CUP2013000041A patent/CU24182B1/es active IP Right Grant
- 2011-09-16 KR KR1020137006766A patent/KR101907222B1/ko active IP Right Grant
- 2011-09-16 US US13/822,706 patent/US9084749B2/en active Active
- 2011-09-16 UA UAA201303087A patent/UA112297C2/uk unknown
- 2011-09-16 LT LTEP18161921.4T patent/LT3360569T/lt unknown
- 2011-09-16 SG SG2013020102A patent/SG188595A1/en unknown
- 2011-09-16 PT PT181619214T patent/PT3360569T/pt unknown
- 2011-09-16 HU HUE11755362A patent/HUE039038T2/hu unknown
- 2011-09-16 RS RS20200356A patent/RS60146B1/sr unknown
- 2011-09-16 BR BR112013006245A patent/BR112013006245A2/pt not_active Application Discontinuation
- 2011-09-16 LT LTEP11755362.8T patent/LT2618837T/lt unknown
- 2011-09-16 SI SI201131557T patent/SI2618837T1/sl unknown
- 2011-09-16 PL PL11755362T patent/PL2618837T3/pl unknown
- 2011-09-16 MX MX2013002989A patent/MX346708B/es active IP Right Grant
- 2011-09-16 HU HUE18161921A patent/HUE048774T2/hu unknown
- 2011-09-16 PT PT11755362T patent/PT2618837T/pt unknown
- 2011-09-16 SI SI201131865T patent/SI3360569T1/sl unknown
- 2011-09-16 EP EP18161921.4A patent/EP3360569B1/en active Active
- 2011-09-16 ES ES11755362.8T patent/ES2685928T3/es active Active
- 2011-09-16 CN CN2011800450826A patent/CN103118703A/zh active Pending
- 2011-09-16 CA CA2811158A patent/CA2811158C/en active Active
- 2011-09-16 JP JP2013528689A patent/JP5919276B2/ja active Active
- 2011-09-16 EA EA201300380A patent/EA026661B1/ru not_active IP Right Cessation
- 2011-09-16 WO PCT/EP2011/066131 patent/WO2012038348A1/en active Application Filing
- 2011-09-16 ES ES18161921T patent/ES2784451T3/es active Active
- 2011-09-16 DK DK11755362.8T patent/DK2618837T3/en active
- 2011-09-16 PL PL18161921T patent/PL3360569T3/pl unknown
- 2011-09-16 DK DK18161921.4T patent/DK3360569T3/da active
- 2011-09-16 EP EP11755362.8A patent/EP2618837B1/en active Active
- 2011-09-16 RS RS20180978A patent/RS57574B1/sr unknown
-
2013
- 2013-02-15 ZA ZA2013/01187A patent/ZA201301187B/en unknown
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2018
- 2018-08-29 HR HRP20181387TT patent/HRP20181387T1/hr unknown
- 2018-09-04 CY CY181100918T patent/CY1120748T1/el unknown
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2019
- 2019-01-18 HK HK19100962.3A patent/HK1258603A1/zh unknown
-
2020
- 2020-04-07 CY CY20201100331T patent/CY1123049T1/el unknown
- 2020-04-09 HR HRP20200610TT patent/HRP20200610T1/hr unknown
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