UA105193C2 - Вектор, содержащий две гомологические нуклеотидные последовательности - Google Patents

Вектор, содержащий две гомологические нуклеотидные последовательности

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Publication number
UA105193C2
UA105193C2 UAA201107752A UAA201107752A UA105193C2 UA 105193 C2 UA105193 C2 UA 105193C2 UA A201107752 A UAA201107752 A UA A201107752A UA A201107752 A UAA201107752 A UA A201107752A UA 105193 C2 UA105193 C2 UA 105193C2
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Ukraine
Prior art keywords
homological
nucleotide sequences
vector containing
bases
sequences
Prior art date
Application number
UAA201107752A
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English (en)
Ukrainian (uk)
Inventor
Робин Штайгервальд
Original Assignee
Бавариан Нордик А/С
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Publication date
Application filed by Бавариан Нордик А/С filed Critical Бавариан Нордик А/С
Publication of UA105193C2 publication Critical patent/UA105193C2/ru

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
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  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к векторам, содержащим две гомологические нуклеотидные последовательности, и к способам их получения путем замещения оснований в гомологических последовательностях на другие основания, таким образом, чтобы не изменять кодированную аминокислотную последовательность. При этом снижается внутримолекулярная рекомбинация между гомологическими нуклеотидными последовательностями, особенно в клетках млекопитающих.
UAA201107752A 2008-11-21 2009-11-20 Вектор, содержащий две гомологические нуклеотидные последовательности UA105193C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11667208P 2008-11-21 2008-11-21
PCT/EP2009/008275 WO2010057650A1 (en) 2008-11-21 2009-11-20 Vector comprising multiple homologous nucleotide sequences

Publications (1)

Publication Number Publication Date
UA105193C2 true UA105193C2 (ru) 2014-04-25

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ID=40547753

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201107752A UA105193C2 (ru) 2008-11-21 2009-11-20 Вектор, содержащий две гомологические нуклеотидные последовательности

Country Status (18)

Country Link
US (4) US8999637B2 (ru)
EP (1) EP2352834B1 (ru)
JP (2) JP2012509073A (ru)
KR (1) KR101702956B1 (ru)
CN (2) CN102325888B (ru)
AU (1) AU2009317517B2 (ru)
CA (1) CA2742247C (ru)
DK (1) DK2352834T3 (ru)
EA (1) EA024749B1 (ru)
ES (1) ES2618103T3 (ru)
HK (1) HK1160884A1 (ru)
IL (1) IL211498A (ru)
MX (1) MX2011005171A (ru)
MY (1) MY161849A (ru)
NZ (2) NZ591662A (ru)
UA (1) UA105193C2 (ru)
WO (1) WO2010057650A1 (ru)
ZA (1) ZA201306331B (ru)

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EP2752199A4 (en) 2011-08-29 2015-04-29 Univ Tokushima RSV MUCOSA VACCINE
CA2870293C (en) * 2012-04-12 2023-05-09 The Trustees Of The University Of Pennsylvania Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
EP3656396A1 (en) 2012-08-01 2020-05-27 Bavarian Nordic A/S Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine
US20140099445A1 (en) 2012-10-09 2014-04-10 University Of Massachusetts Method for producing a film having a nano-structure on the surface of the film
WO2014097762A1 (ja) * 2012-12-20 2014-06-26 国立大学法人熊本大学 高病原性トリインフルエンザに対する抗体
US10364465B2 (en) 2013-11-12 2019-07-30 Life Technologies Corporation Reagents and methods for sequencing
MX2017002890A (es) * 2014-09-03 2017-11-13 Bavarian Nordic As Métodos y composiciones para potenciar respuestas inmunitarias.
HRP20240163T1 (hr) 2014-09-03 2024-04-12 Bavarian Nordic A/S Metode i pripravci za izazivanje zaštitnog imuniteta protiv infekcije filovirusom
SG10201901735XA (en) 2014-09-03 2019-03-28 Bavarian Nordic As Recombinant modified vaccinia virus ankara (mva) filovirus vaccine
FR3042121A1 (fr) 2015-10-08 2017-04-14 Jean-Marc Limacher Composition anti-tumorale
WO2018011768A1 (en) 2016-07-15 2018-01-18 Janssen Vaccines And Prevention B.V. Methods and compositions for inducing protective immunity against a marburg virus infection
WO2018185732A1 (en) 2017-04-06 2018-10-11 Janssen Vaccines & Prevention B.V. Mva-bn and ad26.zebov or ad26.filo prime-boost regimen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE160377T1 (de) 1989-04-18 1997-12-15 Applied Biotechnology Inc Erzeugung von hybrid-genen und proteinen durch rekombination mittels viren
DE19629828A1 (de) * 1996-07-24 1998-01-29 Bayer Ag Carbanilide
FR2774699B1 (fr) * 1997-11-17 2003-10-03 Rhone Poulenc Rorer Sa Methode de reduction des evenements de recombinaison homologue
EP1456230A2 (en) 2001-12-04 2004-09-15 Bavarian Nordic A/S Flavivirus ns1 subunit vaccine
US7501127B2 (en) 2002-05-16 2009-03-10 Bavarian Nordic A/S Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
JP4895505B2 (ja) * 2002-05-16 2012-03-14 バヴァリアン・ノルディック・アクティーゼルスカブ 変異ワクシニアウイルスアンカラ（ｍｖａ）ゲノム中の挿入部位としての遺伝子間領域
ES2288634T3 (es) 2002-11-25 2008-01-16 Bavarian Nordic A/S Poxvirus recombinante que comprende al menos dos promotores ati de la viruela de las vacas.
AU2009319336B2 (en) 2008-11-27 2015-03-26 Bavarian Nordic A/S Promoters for recombinant viral expression

Also Published As

Publication number Publication date
MX2011005171A (es) 2011-05-30
CN106318978A (zh) 2017-01-11
US9540660B2 (en) 2017-01-10
ZA201306331B (en) 2016-07-27
NZ602322A (en) 2013-12-20
JP2012509073A (ja) 2012-04-19
US20190055582A1 (en) 2019-02-21
MY161849A (en) 2017-05-15
AU2009317517B2 (en) 2014-12-04
EA024749B1 (ru) 2016-10-31
CN102325888A (zh) 2012-01-18
HK1160884A1 (zh) 2012-08-17
EP2352834B1 (en) 2016-12-21
IL211498A0 (en) 2011-05-31
US11225673B2 (en) 2022-01-18
US20160017369A1 (en) 2016-01-21
CN106318978B (zh) 2020-06-23
KR101702956B1 (ko) 2017-02-06
CN102325888B (zh) 2016-09-07
JP6316227B2 (ja) 2018-04-25
WO2010057650A1 (en) 2010-05-27
US8999637B2 (en) 2015-04-07
EA201170715A1 (ru) 2012-03-30
US20170211098A1 (en) 2017-07-27
US20110236976A1 (en) 2011-09-29
IL211498A (en) 2016-06-30
NZ591662A (en) 2012-10-26
EP2352834A1 (en) 2011-08-10
KR20110105780A (ko) 2011-09-27
JP2015128443A (ja) 2015-07-16
US10072274B2 (en) 2018-09-11
ES2618103T3 (es) 2017-06-20
DK2352834T3 (en) 2017-03-13
CA2742247A1 (en) 2010-05-27
AU2009317517A1 (en) 2010-05-27
CA2742247C (en) 2017-07-04

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