TWI871271B - 海藻糖磷酸化酶 - Google Patents

海藻糖磷酸化酶 Download PDF

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Publication number
TWI871271B
TWI871271B TW106141420A TW106141420A TWI871271B TW I871271 B TWI871271 B TW I871271B TW 106141420 A TW106141420 A TW 106141420A TW 106141420 A TW106141420 A TW 106141420A TW I871271 B TWI871271 B TW I871271B
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TW
Taiwan
Prior art keywords
amino acid
seq
substitution
trehalose phosphorylase
acid positions
Prior art date
Application number
TW106141420A
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English (en)
Chinese (zh)
Other versions
TW201819627A (zh
Inventor
博吉特 波荷
安德列亞斯 甫格
Original Assignee
德商Ｃ 樂克塔股份有限公司
美商紐馬塔宏有限公司
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Application filed by 德商Ｃ 樂克塔股份有限公司, 美商紐馬塔宏有限公司 filed Critical 德商Ｃ 樂克塔股份有限公司
Publication of TW201819627A publication Critical patent/TW201819627A/zh
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Publication of TWI871271B publication Critical patent/TWI871271B/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01231—Alpha,alpha-trehalose phosphorylase (configuration-retaining) (2.4.1.231)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW106141420A 2016-11-28 2017-11-28 海藻糖磷酸化酶 TWI871271B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
??16002528.4 2016-11-28
EP16002528.4 2016-11-28
EP16002528 2016-11-28

Publications (2)

Publication Number Publication Date
TW201819627A TW201819627A (zh) 2018-06-01
TWI871271B true TWI871271B (zh) 2025-02-01

Family

ID=57460297

Family Applications (1)

Application Number Title Priority Date Filing Date
TW106141420A TWI871271B (zh) 2016-11-28 2017-11-28 海藻糖磷酸化酶

Country Status (15)

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US (2) US11142749B2 (https=)
EP (1) EP3545084B1 (https=)
JP (3) JP2019535331A (https=)
KR (1) KR102475231B1 (https=)
CN (1) CN110506111B (https=)
AU (1) AU2017365631B2 (https=)
CA (1) CA3034627A1 (https=)
DK (1) DK3545084T3 (https=)
ES (1) ES3052614T3 (https=)
MY (1) MY191843A (https=)
PH (1) PH12019501164A1 (https=)
PT (1) PT3545084T (https=)
SI (1) SI3545084T1 (https=)
TW (1) TWI871271B (https=)
WO (1) WO2018096169A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI841543B (zh) * 2017-11-28 2024-05-11 德商Ｃ 樂克塔股份有限公司 生產海藻糖之方法
CN119391663B (zh) * 2024-09-18 2025-09-26 南京大学 高产诺卡酮的醇脱氢酶突变体及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020068349A1 (en) * 1997-03-31 2002-06-06 Sueharu Horinouchi Gene encoding recombinant trehalose phosphorylase, vector containing the gene, transformant transformed by the gene, and method for producing recombinant trehalose phosphorylase with the use of transformant

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0724629A1 (de) * 1993-10-18 1996-08-07 Degussa Aktiengesellschaft Verfahren zur gezielten veränderung von enzymen, veränderte enzyme und deren verwendung
JP3563104B2 (ja) * 1994-03-23 2004-09-08 呉羽化学工業株式会社 トレハロースホスホリラーゼおよびその製造法
DE69532106T2 (de) * 1994-09-16 2004-07-22 Nihon Shokuhin Kako Co., Ltd. Maltose Phospharylase, Trehalose Phophorylase, Plesiomonasstamm, und Herstellung von Trehalose
IN1997CH00924A (en) * 1996-05-03 2005-03-04 Syngenta Mogen Bv Regulating metabolism by modifying the level of trehalose-6-phosphate
KR20020089548A (ko) * 2001-05-23 2002-11-29 주식회사 싸이젠하베스트 설폴로버스 하코네시스로부터 분리된 트레할로스 합성관여 유전자 및 이들의 단백질
JP4340107B2 (ja) * 2003-07-17 2009-10-07 株式会社林原生物化学研究所 基質特異性改変キメラ酵素
EP1661985B1 (en) * 2003-09-04 2017-09-27 Ezaki Glico Co., Ltd. Method of making sucrose phosphorylase (sp) heat-stable
JP2011517931A (ja) * 2008-02-27 2011-06-23 バテル エナジー アライアンス，エルエルシー アリサイクロバチルス・アシドカルダリウスおよび関連生物体からの好熱性および好熱好酸性グリコシル化遺伝子および酵素、方法
CN102317309A (zh) * 2009-02-26 2012-01-11 巴特勒能源同盟有限公司 通过不同的翻译后修饰改变和调节蛋白质活性
BRPI1014253A2 (pt) * 2009-07-02 2016-04-12 Merz Pharma Gmbh & Co Kgaa polinucleotídeo codificado um polipeptídeo de neurotoxina, vetor, célula hospedeira, anticorpo, uso de um polinucleotídeo, método para a fabricação de um polipeptídeo de neurotoxina e método para a fabricação de um medicamento
KR20120126061A (ko) * 2009-10-22 2012-11-20 재단법인 작물유전체기능연구사업단 향상된 수확량 관련 형질을 갖는 식물 및 이의 제조 방법
US20130029384A1 (en) 2010-04-06 2013-01-31 Universiteit Gent Thermostable sucrose phosphorylase
WO2012080100A1 (en) * 2010-12-14 2012-06-21 Universiteit Gent Trehalose phosphorylases and their use in the biocatalytic production of trehalose-analogues and glycosyl phosphates
CN103642899A (zh) * 2013-06-28 2014-03-19 广西大学 一种编码6-磷酸海藻糖磷酸酶的基因的用途

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020068349A1 (en) * 1997-03-31 2002-06-06 Sueharu Horinouchi Gene encoding recombinant trehalose phosphorylase, vector containing the gene, transformant transformed by the gene, and method for producing recombinant trehalose phosphorylase with the use of transformant

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
網路文獻 Ohm, R. A. et al., Accession No. EFJ00254.1, glycosyltransferase family 4 protein [Schizophyllum commune H4-8], 2015/03/13 updated, Database GenBank, https://www.ncbi.nlm.nih.gov/protein/300108852?sat=37&satkey=263503860 *

Also Published As

Publication number Publication date
TW201819627A (zh) 2018-06-01
CA3034627A1 (en) 2018-05-31
US20210380954A1 (en) 2021-12-09
JP7436549B2 (ja) 2024-02-21
US20190276808A1 (en) 2019-09-12
EP3545084B1 (en) 2025-08-27
US11142749B2 (en) 2021-10-12
ES3052614T3 (en) 2026-01-12
SI3545084T1 (sl) 2026-02-27
JP2019535331A (ja) 2019-12-12
DK3545084T3 (da) 2025-12-01
PT3545084T (pt) 2025-11-17
JP2024036628A (ja) 2024-03-15
CN110506111A (zh) 2019-11-26
AU2017365631A1 (en) 2019-03-21
CN110506111B (zh) 2024-08-23
US12173331B2 (en) 2024-12-24
PH12019501164A1 (en) 2019-07-29
KR20190085944A (ko) 2019-07-19
EP3545084A1 (en) 2019-10-02
KR102475231B1 (ko) 2022-12-06
JP2022088509A (ja) 2022-06-14
AU2017365631B2 (en) 2024-02-01
MY191843A (en) 2022-07-18
WO2018096169A1 (en) 2018-05-31

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