AU2017365631B2 - Trehalose phosphorylase - Google Patents

Trehalose phosphorylase Download PDF

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Publication number
AU2017365631B2
AU2017365631B2 AU2017365631A AU2017365631A AU2017365631B2 AU 2017365631 B2 AU2017365631 B2 AU 2017365631B2 AU 2017365631 A AU2017365631 A AU 2017365631A AU 2017365631 A AU2017365631 A AU 2017365631A AU 2017365631 B2 AU2017365631 B2 AU 2017365631B2
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AU
Australia
Prior art keywords
amino acid
seq
substitution
trehalose phosphorylase
acid positions
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AU2017365631A
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AU2017365631A1 (en
Inventor
Birgit BRUCHER
Andreas Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C Lecta GmbH
New Matterhorn LLC
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C Lecta GmbH
New Matterhorn LLC
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Publication of AU2017365631A1 publication Critical patent/AU2017365631A1/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01231—Alpha,alpha-trehalose phosphorylase (configuration-retaining) (2.4.1.231)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2017365631A 2016-11-28 2017-11-28 Trehalose phosphorylase Active AU2017365631B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16002528.4 2016-11-28
EP16002528 2016-11-28
PCT/EP2017/080650 WO2018096169A1 (en) 2016-11-28 2017-11-28 Trehalose phosphorylase

Publications (2)

Publication Number Publication Date
AU2017365631A1 AU2017365631A1 (en) 2019-03-21
AU2017365631B2 true AU2017365631B2 (en) 2024-02-01

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ID=57460297

Family Applications (1)

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AU2017365631A Active AU2017365631B2 (en) 2016-11-28 2017-11-28 Trehalose phosphorylase

Country Status (15)

Country Link
US (2) US11142749B2 (https=)
EP (1) EP3545084B1 (https=)
JP (3) JP2019535331A (https=)
KR (1) KR102475231B1 (https=)
CN (1) CN110506111B (https=)
AU (1) AU2017365631B2 (https=)
CA (1) CA3034627A1 (https=)
DK (1) DK3545084T3 (https=)
ES (1) ES3052614T3 (https=)
MY (1) MY191843A (https=)
PH (1) PH12019501164A1 (https=)
PT (1) PT3545084T (https=)
SI (1) SI3545084T1 (https=)
TW (1) TWI871271B (https=)
WO (1) WO2018096169A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI841543B (zh) * 2017-11-28 2024-05-11 德商Ｃ 樂克塔股份有限公司 生產海藻糖之方法
CN119391663B (zh) * 2024-09-18 2025-09-26 南京大学 高产诺卡酮的醇脱氢酶突变体及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0724629A1 (de) * 1993-10-18 1996-08-07 Degussa Aktiengesellschaft Verfahren zur gezielten veränderung von enzymen, veränderte enzyme und deren verwendung
JP3563104B2 (ja) * 1994-03-23 2004-09-08 呉羽化学工業株式会社 トレハロースホスホリラーゼおよびその製造法
DE69532106T2 (de) * 1994-09-16 2004-07-22 Nihon Shokuhin Kako Co., Ltd. Maltose Phospharylase, Trehalose Phophorylase, Plesiomonasstamm, und Herstellung von Trehalose
IN1997CH00924A (en) * 1996-05-03 2005-03-04 Syngenta Mogen Bv Regulating metabolism by modifying the level of trehalose-6-phosphate
JPH10276785A (ja) * 1997-03-31 1998-10-20 Kureha Chem Ind Co Ltd 組換え型トレハロースホスホリラーゼをコードする遺伝子、その遺伝子を含むベクター、その遺伝子で形質転換された形質転換体及びこの形質転換体を用いて組換え型トレハロースホスホリラーゼを製造する方法
KR20020089548A (ko) * 2001-05-23 2002-11-29 주식회사 싸이젠하베스트 설폴로버스 하코네시스로부터 분리된 트레할로스 합성관여 유전자 및 이들의 단백질
JP4340107B2 (ja) * 2003-07-17 2009-10-07 株式会社林原生物化学研究所 基質特異性改変キメラ酵素
EP1661985B1 (en) * 2003-09-04 2017-09-27 Ezaki Glico Co., Ltd. Method of making sucrose phosphorylase (sp) heat-stable
JP2011517931A (ja) * 2008-02-27 2011-06-23 バテル エナジー アライアンス，エルエルシー アリサイクロバチルス・アシドカルダリウスおよび関連生物体からの好熱性および好熱好酸性グリコシル化遺伝子および酵素、方法
CN102317309A (zh) * 2009-02-26 2012-01-11 巴特勒能源同盟有限公司 通过不同的翻译后修饰改变和调节蛋白质活性
BRPI1014253A2 (pt) * 2009-07-02 2016-04-12 Merz Pharma Gmbh & Co Kgaa polinucleotídeo codificado um polipeptídeo de neurotoxina, vetor, célula hospedeira, anticorpo, uso de um polinucleotídeo, método para a fabricação de um polipeptídeo de neurotoxina e método para a fabricação de um medicamento
KR20120126061A (ko) * 2009-10-22 2012-11-20 재단법인 작물유전체기능연구사업단 향상된 수확량 관련 형질을 갖는 식물 및 이의 제조 방법
US20130029384A1 (en) 2010-04-06 2013-01-31 Universiteit Gent Thermostable sucrose phosphorylase
WO2012080100A1 (en) * 2010-12-14 2012-06-21 Universiteit Gent Trehalose phosphorylases and their use in the biocatalytic production of trehalose-analogues and glycosyl phosphates
CN103642899A (zh) * 2013-06-28 2014-03-19 广西大学 一种编码6-磷酸海藻糖磷酸酶的基因的用途

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE UniProt [online] 5 October 2010 (2010-10-05), "SubName: Full=Glycosyltransferase family 4 protein {ECO:0000313|EMBL:EFJ00254.1};", XP002767750, retrieved from EBI accession no. UNIPROT:D8PWQ7 Database accession no. D8PWQ7 *
DATABASE UniProt [online] 8 June 2016 (2016-06-08), "SubName: Full=Trehalose phosphorylase {ECO:0000313|EMBL:KYQ39707.1};", XP002767751, retrieved from EBI accession no. UNIPROT:A0A151VW19 Database accession no. A0A151VW19 *

Also Published As

Publication number Publication date
TW201819627A (zh) 2018-06-01
CA3034627A1 (en) 2018-05-31
US20210380954A1 (en) 2021-12-09
JP7436549B2 (ja) 2024-02-21
US20190276808A1 (en) 2019-09-12
TWI871271B (zh) 2025-02-01
EP3545084B1 (en) 2025-08-27
US11142749B2 (en) 2021-10-12
ES3052614T3 (en) 2026-01-12
SI3545084T1 (sl) 2026-02-27
JP2019535331A (ja) 2019-12-12
DK3545084T3 (da) 2025-12-01
PT3545084T (pt) 2025-11-17
JP2024036628A (ja) 2024-03-15
CN110506111A (zh) 2019-11-26
AU2017365631A1 (en) 2019-03-21
CN110506111B (zh) 2024-08-23
US12173331B2 (en) 2024-12-24
PH12019501164A1 (en) 2019-07-29
KR20190085944A (ko) 2019-07-19
EP3545084A1 (en) 2019-10-02
KR102475231B1 (ko) 2022-12-06
JP2022088509A (ja) 2022-06-14
MY191843A (en) 2022-07-18
WO2018096169A1 (en) 2018-05-31

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