TWI814709B - 保存效果或光穩定性經改善之眼科藥用組成物 - Google Patents

保存效果或光穩定性經改善之眼科藥用組成物 Download PDF

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Publication number
TWI814709B
TWI814709B TW106128430A TW106128430A TWI814709B TW I814709 B TWI814709 B TW I814709B TW 106128430 A TW106128430 A TW 106128430A TW 106128430 A TW106128430 A TW 106128430A TW I814709 B TWI814709 B TW I814709B
Authority
TW
Taiwan
Prior art keywords
pharmaceutically acceptable
carteolol
acceptable salt
solution
edetate
Prior art date
Application number
TW106128430A
Other languages
English (en)
Chinese (zh)
Other versions
TW201811331A (zh
Inventor
長濱良治
近藤文雄
大八木優
平田雄樹
Original Assignee
日商大塚製藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商大塚製藥股份有限公司 filed Critical 日商大塚製藥股份有限公司
Publication of TW201811331A publication Critical patent/TW201811331A/zh
Application granted granted Critical
Publication of TWI814709B publication Critical patent/TWI814709B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW106128430A 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物 TWI814709B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016-162611 2016-08-23
JP2016162611 2016-08-23

Publications (2)

Publication Number Publication Date
TW201811331A TW201811331A (zh) 2018-04-01
TWI814709B true TWI814709B (zh) 2023-09-11

Family

ID=59812062

Family Applications (4)

Application Number Title Priority Date Filing Date
TW106128430A TWI814709B (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物
TW113131450A TW202513068A (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物
TW112113506A TW202332446A (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物
TW110149715A TWI828025B (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物

Family Applications After (3)

Application Number Title Priority Date Filing Date
TW113131450A TW202513068A (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物
TW112113506A TW202332446A (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物
TW110149715A TWI828025B (zh) 2016-08-23 2017-08-22 保存效果或光穩定性經改善之眼科藥用組成物

Country Status (4)

Country Link
JP (3) JP7123034B2 (OSRAM)
CN (3) CN109641059B (OSRAM)
TW (4) TWI814709B (OSRAM)
WO (1) WO2018038102A1 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022131565A (ja) * 2021-02-26 2022-09-07 ロート製薬株式会社 水性医薬組成物
CN114788809B (zh) * 2022-01-25 2023-04-14 江苏广承药业有限公司 一种氯雷他定液体制剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8772337B2 (en) * 2007-07-20 2014-07-08 Laboratoires Thea Preservative-free prostaglandin-based ophthalmic solution

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01135887A (ja) * 1987-11-20 1989-05-29 Lion Corp 紫外線吸収剤組成物
FR2777189B1 (fr) * 1998-04-09 2001-04-06 Chauvin Lab Sa Composition ophtalmique comprenant un beta-bloquant
JP4361294B2 (ja) * 2003-02-25 2009-11-11 ロート製薬株式会社 ケトチフェン含有組成物
JP5711957B2 (ja) * 2003-09-30 2015-05-07 ロート製薬株式会社 透明包装体入りトラニラスト含有医薬製剤
KR20060102282A (ko) * 2005-03-22 2006-09-27 테이카 세이야쿠 가부시키가이샤 점안제
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
EP2269612A4 (en) * 2008-04-23 2013-07-31 Otsuka Pharma Co Ltd EYE DROP PREPARATION AND ITS USE
CN101461780A (zh) 2009-01-06 2009-06-24 河北科技大学 不含抑菌剂的盐酸卡替洛尔滴眼液及其制备方法
TW201109325A (en) 2009-07-30 2011-03-16 Wakamoto Pharma Co Ltd Aqueous composition for eye drops
KR20130100273A (ko) * 2010-08-27 2013-09-10 와카모토 세이야꾸 가부시끼가이샤 점안용 수성 조성물
HK1200110A1 (en) * 2012-02-27 2015-07-31 日本乐敦制药株式会社 Ophthalmic composition kit

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8772337B2 (en) * 2007-07-20 2014-07-08 Laboratoires Thea Preservative-free prostaglandin-based ophthalmic solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
期刊 Sechoy, Odile, et al. "A new long acting ophthalmic formulation of carteolol containing alginic acid.", International journal of pharmaceutics, 207(1-2), 109-116. 2000. *

Also Published As

Publication number Publication date
JP2024112862A (ja) 2024-08-21
CN115444849A (zh) 2022-12-09
TW202513068A (zh) 2025-04-01
TW201811331A (zh) 2018-04-01
JP7123034B2 (ja) 2022-08-22
CN109641059B (zh) 2022-08-30
WO2018038102A1 (en) 2018-03-01
TW202332446A (zh) 2023-08-16
JP2019526549A (ja) 2019-09-19
CN115463130A (zh) 2022-12-13
TWI828025B (zh) 2024-01-01
CN109641059A (zh) 2019-04-16
JP2022172124A (ja) 2022-11-15
TW202231276A (zh) 2022-08-16
CN115444849B (zh) 2025-07-01

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