TWI813560B - 利用鹼性化劑的血液淨化 - Google Patents

利用鹼性化劑的血液淨化 Download PDF

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Publication number
TWI813560B
TWI813560B TW107108443A TW107108443A TWI813560B TW I813560 B TWI813560 B TW I813560B TW 107108443 A TW107108443 A TW 107108443A TW 107108443 A TW107108443 A TW 107108443A TW I813560 B TWI813560 B TW I813560B
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TW
Taiwan
Prior art keywords
pharmaceutical composition
concentration
acid
urine
alkalinizing agent
Prior art date
Application number
TW107108443A
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English (en)
Chinese (zh)
Other versions
TW201838684A (zh
Inventor
阿部倫明
小柴生造
西岡浩一郎
川口和彦
山崎里美
寺中康行
Original Assignee
國立大學法人東北大學
日商日本化美化股份有限公司
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Publication date
Priority claimed from JP2017085741A external-priority patent/JP7578234B2/ja
Priority claimed from PCT/JP2017/032931 external-priority patent/WO2018193648A1/ja
Application filed by 國立大學法人東北大學, 日商日本化美化股份有限公司 filed Critical 國立大學法人東北大學
Publication of TW201838684A publication Critical patent/TW201838684A/zh
Application granted granted Critical
Publication of TWI813560B publication Critical patent/TWI813560B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TW107108443A 2017-04-18 2018-03-13 利用鹼性化劑的血液淨化 TWI813560B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2017-082423 2017-04-18
JP2017082423 2017-04-18
JP2017085741A JP7578234B2 (ja) 2017-04-18 2017-04-24 アルカリ性化剤による血液浄化
JP2017-085741 2017-04-24
JP2017103935 2017-05-25
JP2017-103935 2017-05-25
PCT/JP2017/032931 WO2018193648A1 (ja) 2017-04-18 2017-09-12 アルカリ性化剤による血液浄化
WOPCT/JP2017/032931 2017-09-12
??PCT/JP2017/032931 2017-09-12

Publications (2)

Publication Number Publication Date
TW201838684A TW201838684A (zh) 2018-11-01
TWI813560B true TWI813560B (zh) 2023-09-01

Family

ID=65033758

Family Applications (1)

Application Number Title Priority Date Filing Date
TW107108443A TWI813560B (zh) 2017-04-18 2018-03-13 利用鹼性化劑的血液淨化

Country Status (8)

Country Link
US (1) US20210121426A1 (enExample)
EP (1) EP3616721B1 (enExample)
JP (3) JP7219898B2 (enExample)
KR (1) KR102685723B1 (enExample)
CN (1) CN110799214A (enExample)
AU (1) AU2018254884C1 (enExample)
CA (1) CA3060154A1 (enExample)
TW (1) TWI813560B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112203686A (zh) * 2018-05-25 2021-01-08 国立大学法人琉球大学 代谢改善剂
US12324793B2 (en) 2018-10-17 2025-06-10 Tohoku University Method for renal protection
JPWO2021193856A1 (enExample) * 2020-03-26 2021-09-30
CN114794346A (zh) * 2022-04-25 2022-07-29 武汉汇天诚科技有限公司 一种复合固体饮料的配方

Citations (3)

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JP2007217366A (ja) * 2006-02-17 2007-08-30 Kirin Brewery Co Ltd 尿酸値降下用組成物
JP4087929B2 (ja) * 1997-08-27 2008-05-21 日清ペットフード株式会社 猫慢性腎不全治療用組成物及びその治療方法
CN101374416A (zh) * 2006-01-30 2009-02-25 环亚有限公司 逆转、防止、延迟或稳定软组织钙化的方法

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JPS60105619A (ja) * 1983-11-15 1985-06-11 Nippon Chemiphar Co Ltd 尿アルカリ化性食品組成物
JP2004131406A (ja) * 2002-10-09 2004-04-30 Sekisui Chem Co Ltd 尿毒症性物質特異的認識ポリマー及び経口吸着剤
US20100266712A1 (en) * 2007-05-24 2010-10-21 Austin Health Prevention of Acute Kidney Injury
EP2194977A1 (en) 2007-08-31 2010-06-16 C.B. Fleet Company Incorporated Method of preventing nephrocalcinosis
WO2010126146A1 (ja) * 2009-04-30 2010-11-04 Tanaka Noriaki 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
JP6164719B2 (ja) * 2009-10-27 2017-07-19 エイワイファーマ株式会社 白金含有薬剤投与による腎障害の軽減剤
CN105671120B (zh) * 2010-07-05 2019-02-19 株式会社明治 具有肠内腐败物质的减少作用的双歧杆菌
MX357998B (es) * 2015-03-20 2018-07-11 Antonio Hernandez Miramontes Jorge Una mezcla de acidos carboxilicos, especificamente acido citrico, acido succinico, acido fumarico y acido malico para el tratamiento de pacientes con insuficiencia renal cronica, insuficiencia renal aguda, hepatopatias agudas o cronicas que cursen con hiperamonemia, enfermedades congenitas con alteraciones enzimaticas en el ciclo de la urea, asi como condiciones clínicas que cursen con balance nitrogenado negativo.
JP6490614B2 (ja) * 2015-03-30 2019-03-27 景博 内田 インドキシル硫酸の測定方法
US12324793B2 (en) * 2018-10-17 2025-06-10 Tohoku University Method for renal protection
CA3116290A1 (en) * 2018-10-17 2020-04-23 Nippon Chemiphar Co., Ltd. Therapeutic or prophylactic agent for nocturnal polyuria
EP3964264A4 (en) * 2019-04-28 2023-07-12 Tohoku University NOVEL PHARMACEUTICAL COMPOSITION

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4087929B2 (ja) * 1997-08-27 2008-05-21 日清ペットフード株式会社 猫慢性腎不全治療用組成物及びその治療方法
CN101374416A (zh) * 2006-01-30 2009-02-25 环亚有限公司 逆转、防止、延迟或稳定软组织钙化的方法
JP2007217366A (ja) * 2006-02-17 2007-08-30 Kirin Brewery Co Ltd 尿酸値降下用組成物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
期刊 Igor Łoniewski1 and Donald E. Wesson, "Bicarbonate therapy for prevention of chronic kidney disease progression", Kidney International, 85, 無, 2014, 529–535. *
網路文獻 內衛藥製字第001727號許可證資料; *
網路文獻 衛署藥製字第041577號許可證資料; *

Also Published As

Publication number Publication date
AU2018254884B2 (en) 2023-12-14
US20210121426A1 (en) 2021-04-29
AU2018254884C1 (en) 2024-04-11
JP7756863B2 (ja) 2025-10-21
AU2018254884A1 (en) 2019-11-07
KR20190137147A (ko) 2019-12-10
JPWO2018193648A1 (ja) 2020-02-27
JPWO2018193752A1 (ja) 2020-03-05
EP3616721A1 (en) 2020-03-04
KR102685723B1 (ko) 2024-07-16
CA3060154A1 (en) 2018-10-25
JP2023115271A (ja) 2023-08-18
EP3616721A4 (en) 2020-12-30
JP7219898B2 (ja) 2023-02-09
CN110799214A (zh) 2020-02-14
EP3616721C0 (en) 2024-12-04
EP3616721B1 (en) 2024-12-04
TW201838684A (zh) 2018-11-01

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