CN110799214A - 利用碱化剂的血液净化 - Google Patents

利用碱化剂的血液净化 Download PDF

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Publication number
CN110799214A
CN110799214A CN201880025628.3A CN201880025628A CN110799214A CN 110799214 A CN110799214 A CN 110799214A CN 201880025628 A CN201880025628 A CN 201880025628A CN 110799214 A CN110799214 A CN 110799214A
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CN
China
Prior art keywords
pharmaceutical composition
concentration
alkalizing agent
urine
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880025628.3A
Other languages
English (en)
Chinese (zh)
Inventor
阿部伦明
小柴生造
西冈浩一郎
川口和彦
山崎里美
寺中康行
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tohoku University NUC
Nippon Chemiphar Co Ltd
Original Assignee
Tohoku University NUC
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2017085741A external-priority patent/JP7578234B2/ja
Priority claimed from PCT/JP2017/032931 external-priority patent/WO2018193648A1/ja
Application filed by Tohoku University NUC, Nippon Chemiphar Co Ltd filed Critical Tohoku University NUC
Publication of CN110799214A publication Critical patent/CN110799214A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201880025628.3A 2017-04-18 2018-03-13 利用碱化剂的血液净化 Pending CN110799214A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2017082423 2017-04-18
JP2017-082423 2017-04-18
JP2017-085741 2017-04-24
JP2017085741A JP7578234B2 (ja) 2017-04-18 2017-04-24 アルカリ性化剤による血液浄化
JP2017103935 2017-05-25
JP2017-103935 2017-05-25
PCT/JP2017/032931 WO2018193648A1 (ja) 2017-04-18 2017-09-12 アルカリ性化剤による血液浄化
JPPCT/JP2017/032931 2017-09-12
PCT/JP2018/009679 WO2018193752A1 (ja) 2017-04-18 2018-03-13 アルカリ性化剤による血液浄化

Publications (1)

Publication Number Publication Date
CN110799214A true CN110799214A (zh) 2020-02-14

Family

ID=65033758

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880025628.3A Pending CN110799214A (zh) 2017-04-18 2018-03-13 利用碱化剂的血液净化

Country Status (8)

Country Link
US (1) US20210121426A1 (enExample)
EP (1) EP3616721B1 (enExample)
JP (3) JP7219898B2 (enExample)
KR (1) KR102685723B1 (enExample)
CN (1) CN110799214A (enExample)
AU (1) AU2018254884C1 (enExample)
CA (1) CA3060154A1 (enExample)
TW (1) TWI813560B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114794346A (zh) * 2022-04-25 2022-07-29 武汉汇天诚科技有限公司 一种复合固体饮料的配方
CN115315258A (zh) * 2020-03-26 2022-11-08 国立大学法人东北大学 肾功能保护剂

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6792848B2 (ja) * 2018-05-25 2020-12-02 国立大学法人 琉球大学 代謝改善剤
JPWO2020080499A1 (ja) 2018-10-17 2021-09-24 国立大学法人東北大学 新規医薬組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016153331A1 (es) * 2015-03-20 2016-09-29 Hernández Miramontes Jorge Antonio Mezcla de ácidos carboxilicos para tratar pacientes con insuficiencia renal

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* Cited by examiner, † Cited by third party
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JPS60105619A (ja) * 1983-11-15 1985-06-11 Nippon Chemiphar Co Ltd 尿アルカリ化性食品組成物
JP4087929B2 (ja) * 1997-08-27 2008-05-21 日清ペットフード株式会社 猫慢性腎不全治療用組成物及びその治療方法
JP2004131406A (ja) 2002-10-09 2004-04-30 Sekisui Chem Co Ltd 尿毒症性物質特異的認識ポリマー及び経口吸着剤
HUE028029T2 (en) * 2006-01-30 2016-11-28 Panion & Bf Biotech Inc Method of treating chronic kidney disease
JP2007217366A (ja) 2006-02-17 2007-08-30 Kirin Brewery Co Ltd 尿酸値降下用組成物
CA2687426A1 (en) * 2007-05-24 2008-11-27 Austin Health Prevention of acute kidney injury
BRPI0816066A2 (pt) * 2007-08-31 2017-05-02 C B Fleet Company Incorporated método de prevenção de nefrocalcinose
WO2010126146A1 (ja) * 2009-04-30 2010-11-04 Tanaka Noriaki 腎疾患重篤度を判定する方法又は装置若しくはその作動方法
JP6164719B2 (ja) 2009-10-27 2017-07-19 エイワイファーマ株式会社 白金含有薬剤投与による腎障害の軽減剤
CN105671120B (zh) 2010-07-05 2019-02-19 株式会社明治 具有肠内腐败物质的减少作用的双歧杆菌
JPWO2020080499A1 (ja) * 2018-10-17 2021-09-24 国立大学法人東北大学 新規医薬組成物
WO2020080399A1 (ja) * 2018-10-17 2020-04-23 日本ケミファ株式会社 夜間多尿の治療又は予防剤
US20220202752A1 (en) * 2019-04-28 2022-06-30 Tohoku University Novel pharmaceutical composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016153331A1 (es) * 2015-03-20 2016-09-29 Hernández Miramontes Jorge Antonio Mezcla de ácidos carboxilicos para tratar pacientes con insuficiencia renal

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
GEORGE A. TANNER AND JUDITH A. TANNER: ""Citrate therapy for polycystic kidney disease in rats"", 《KIDNEY INTERNATIONAL》 *
LONIEWSKI ET AL.: ""Bicarbonate therapy for prevention of chronic kidney disease progression"", 《KIDNEY INTERNATIONAL》 *
NIWA T1: ""Uremic toxicity of indoxyl sulfate"", 《NAGOYA J MED SCI》 *
SOROT PHISITKUL等: ""Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR"", 《KIDNEY INTERNATIONAL》 *
TANNER G A等: ""Potassium Citrate/Citric Acid Intake improves renal function in Rats with Polycystic Kidney Disease"", 《J AM SOC NEPHROL》 *
阿部倫明: ""腎尿細管液の酸性化とアルブミン尿による腎障害機序の解明と新規腎臓病治療戦略の開発"", 《2012 FISCAL YEAR ANNUAL RESEARCH REPORT》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115315258A (zh) * 2020-03-26 2022-11-08 国立大学法人东北大学 肾功能保护剂
CN114794346A (zh) * 2022-04-25 2022-07-29 武汉汇天诚科技有限公司 一种复合固体饮料的配方

Also Published As

Publication number Publication date
TW201838684A (zh) 2018-11-01
JPWO2018193648A1 (ja) 2020-02-27
KR102685723B1 (ko) 2024-07-16
JP7756863B2 (ja) 2025-10-21
KR20190137147A (ko) 2019-12-10
JP7219898B2 (ja) 2023-02-09
EP3616721A1 (en) 2020-03-04
AU2018254884B2 (en) 2023-12-14
JPWO2018193752A1 (ja) 2020-03-05
EP3616721C0 (en) 2024-12-04
AU2018254884C1 (en) 2024-04-11
JP2023115271A (ja) 2023-08-18
TWI813560B (zh) 2023-09-01
US20210121426A1 (en) 2021-04-29
AU2018254884A1 (en) 2019-11-07
EP3616721B1 (en) 2024-12-04
CA3060154A1 (en) 2018-10-25
EP3616721A4 (en) 2020-12-30

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