TWI810284B - 5,5-二取代-4,5-二氫異唑的製造方法 - Google Patents

5,5-二取代-4,5-二氫異唑的製造方法 Download PDF

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Publication number
TWI810284B
TWI810284B TW108114335A TW108114335A TWI810284B TW I810284 B TWI810284 B TW I810284B TW 108114335 A TW108114335 A TW 108114335A TW 108114335 A TW108114335 A TW 108114335A TW I810284 B TWI810284 B TW I810284B
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TW
Taiwan
Prior art keywords
acid
hydroxylamine
formula
compound
reaction
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TW108114335A
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English (en)
Chinese (zh)
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TW201945347A (zh
Inventor
永田俊浩
志鎌大介
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日商組合化學工業股份有限公司
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Publication of TW201945347A publication Critical patent/TW201945347A/zh
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0231Halogen-containing compounds
    • B01J31/0232Halogen-containing compounds also containing elements or functional groups covered by B01J31/0201 - B01J31/0228
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235Nitrogen containing compounds
    • B01J31/0237Amines
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/30Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
    • B01J2231/34Other additions, e.g. Monsanto-type carbonylations, addition to 1,2-C=X or 1,2-C-X triplebonds, additions to 1,4-C=C-C=X or 1,4-C=-C-X triple bonds with X, e.g. O, S, NH/N
    • B01J2231/3481,4-additions, e.g. conjugate additions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/001General concepts, e.g. reviews, relating to catalyst systems and methods of making them, the concept being defined by a common material or method/theory
    • B01J2531/002Materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00Other general methods

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
TW108114335A 2018-04-27 2019-04-24 5,5-二取代-4,5-二氫異唑的製造方法 TWI810284B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018086679 2018-04-27
JP2018-086679 2018-04-27

Publications (2)

Publication Number Publication Date
TW201945347A TW201945347A (zh) 2019-12-01
TWI810284B true TWI810284B (zh) 2023-08-01

Family

ID=68295226

Family Applications (1)

Application Number Title Priority Date Filing Date
TW108114335A TWI810284B (zh) 2018-04-27 2019-04-24 5,5-二取代-4,5-二氫異唑的製造方法

Country Status (8)

Country Link
US (1) US11753384B2 (enExample)
EP (1) EP3789382B1 (enExample)
JP (1) JP7242641B2 (enExample)
CN (1) CN112004805B (enExample)
IL (1) IL278229B2 (enExample)
MX (1) MX2020011267A (enExample)
TW (1) TWI810284B (enExample)
WO (1) WO2019208643A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL275272B (en) * 2017-12-15 2022-08-01 Kumiai Chemical Industry Co Novel method for producing 5,5-disubstituted-4,5-dihydroisoxazole
TWI844692B (zh) 2019-06-14 2024-06-11 日商組合化學工業股份有限公司 二氫異噁唑的製造方法
CN114644602B (zh) * 2020-12-17 2024-09-03 帕潘纳(北京)科技有限公司 二氢异噁唑类化合物的制备方法
CN115073390B (zh) * 2021-03-11 2024-08-06 山东润博生物科技有限公司 一种4,5-二氢异噁唑衍生物及其制备方法和应用
CN116178294A (zh) * 2023-01-08 2023-05-30 湖南吴赣药业有限公司 一种制备5,5-二甲基-4,5-二氢异噁唑的方法
CN117285479B (zh) * 2023-09-26 2024-07-23 山东滨农科技有限公司 一种3-氯-5,5-二甲基-4,5-二氢异噁唑的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200914429A (en) * 2007-08-17 2009-04-01 Du Pont Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
CN102666503A (zh) * 2009-11-26 2012-09-12 巴斯夫欧洲公司 生产5,5-二取代的2-异噁唑啉的方法
CN107652245A (zh) * 2017-08-24 2018-02-02 郑州手性药物研究院有限公司 手性双苯噁唑酸乙酯化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1174429A4 (en) 1999-03-29 2002-07-03 Nippon Soda Co METHOD FOR PRODUCING (E) -3- (1-PROPENYL) ISOXAZOLINE
JP4465133B2 (ja) 2001-02-08 2010-05-19 クミアイ化学工業株式会社 イソオキサゾリン誘導体及びこれを有効成分とする除草剤
EP2632906B1 (en) 2010-10-30 2016-04-06 Lupin Limited Oxazoline and isoxazoline derivatives as crac modulators
IL275272B (en) 2017-12-15 2022-08-01 Kumiai Chemical Industry Co Novel method for producing 5,5-disubstituted-4,5-dihydroisoxazole

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200914429A (en) * 2007-08-17 2009-04-01 Du Pont Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
CN102666503A (zh) * 2009-11-26 2012-09-12 巴斯夫欧洲公司 生产5,5-二取代的2-异噁唑啉的方法
CN107652245A (zh) * 2017-08-24 2018-02-02 郑州手性药物研究院有限公司 手性双苯噁唑酸乙酯化合物及其制备方法和应用

Also Published As

Publication number Publication date
US11753384B2 (en) 2023-09-12
BR112020021818A2 (pt) 2021-02-23
IL278229B2 (en) 2023-11-01
EP3789382A1 (en) 2021-03-10
IL278229B1 (en) 2023-07-01
CN112004805A (zh) 2020-11-27
JP7242641B2 (ja) 2023-03-20
EP3789382A4 (en) 2021-11-24
CN112004805B (zh) 2024-06-14
TW201945347A (zh) 2019-12-01
JPWO2019208643A1 (ja) 2021-05-13
WO2019208643A1 (ja) 2019-10-31
EP3789382B1 (en) 2023-07-05
US20210238150A1 (en) 2021-08-05
MX2020011267A (es) 2020-11-12
IL278229A (enExample) 2020-12-31

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