JP7242641B2 - ５，５－ジ置換－４，５－ジヒドロイソオキサゾールの製造方法 - Google Patents

５，５－ジ置換－４，５－ジヒドロイソオキサゾールの製造方法 Download PDF

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Publication number
JP7242641B2
JP7242641B2 JP2020515529A JP2020515529A JP7242641B2 JP 7242641 B2 JP7242641 B2 JP 7242641B2 JP 2020515529 A JP2020515529 A JP 2020515529A JP 2020515529 A JP2020515529 A JP 2020515529A JP 7242641 B2 JP7242641 B2 JP 7242641B2
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acid
mol
hydroxylamine
formula
compound
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Japanese (ja)
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JPWO2019208643A1 (ja
JPWO2019208643A5 (enExample
Inventor
俊浩 永田
大介 志鎌
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Kumiai Chemical Industry Co Ltd
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Kumiai Chemical Industry Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0231—Halogen-containing compounds
    • B01J31/0232—Halogen-containing compounds also containing elements or functional groups covered by B01J31/0201 - B01J31/0228
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/02—Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
    • B01J31/0234—Nitrogen-, phosphorus-, arsenic- or antimony-containing compounds
    • B01J31/0235—Nitrogen containing compounds
    • B01J31/0237—Amines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/30—Addition reactions at carbon centres, i.e. to either C-C or C-X multiple bonds
    • B01J2231/34—Other additions, e.g. Monsanto-type carbonylations, addition to 1,2-C=X or 1,2-C-X triplebonds, additions to 1,4-C=C-C=X or 1,4-C=-C-X triple bonds with X, e.g. O, S, NH/N
    • B01J2231/348—1,4-additions, e.g. conjugate additions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/001—General concepts, e.g. reviews, relating to catalyst systems and methods of making them, the concept being defined by a common material or method/theory
    • B01J2531/002—Materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2020515529A 2018-04-27 2019-04-24 ５，５－ジ置換－４，５－ジヒドロイソオキサゾールの製造方法 Active JP7242641B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018086679 2018-04-27
JP2018086679 2018-04-27
PCT/JP2019/017459 WO2019208643A1 (ja) 2018-04-27 2019-04-24 ５，５－ジ置換－４，５－ジヒドロイソオキサゾールの製造方法

Publications (3)

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JPWO2019208643A1 JPWO2019208643A1 (ja) 2021-05-13
JPWO2019208643A5 JPWO2019208643A5 (enExample) 2022-12-06
JP7242641B2 true JP7242641B2 (ja) 2023-03-20

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JP2020515529A Active JP7242641B2 (ja) 2018-04-27 2019-04-24 ５，５－ジ置換－４，５－ジヒドロイソオキサゾールの製造方法

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US (1) US11753384B2 (enExample)
EP (1) EP3789382B1 (enExample)
JP (1) JP7242641B2 (enExample)
CN (1) CN112004805B (enExample)
IL (1) IL278229B2 (enExample)
MX (1) MX2020011267A (enExample)
TW (1) TWI810284B (enExample)
WO (1) WO2019208643A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL275272B (en) * 2017-12-15 2022-08-01 Kumiai Chemical Industry Co Novel method for producing 5,5-disubstituted-4,5-dihydroisoxazole
TWI844692B (zh) 2019-06-14 2024-06-11 日商組合化學工業股份有限公司 二氫異噁唑的製造方法
CN114644602B (zh) * 2020-12-17 2024-09-03 帕潘纳(北京)科技有限公司 二氢异噁唑类化合物的制备方法
CN115073390B (zh) * 2021-03-11 2024-08-06 山东润博生物科技有限公司 一种4,5-二氢异噁唑衍生物及其制备方法和应用
CN116178294A (zh) * 2023-01-08 2023-05-30 湖南吴赣药业有限公司 一种制备5,5-二甲基-4,5-二氢异噁唑的方法
CN117285479B (zh) * 2023-09-26 2024-07-23 山东滨农科技有限公司 一种3-氯-5,5-二甲基-4,5-二氢异噁唑的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058290A1 (en) 1999-03-29 2000-10-05 Nippon Soda Co., Ltd. Process for the preparation of (e)-3-(1-propenyl)isoxazoline
JP2013512202A (ja) 2009-11-26 2013-04-11 ビーエーエスエフ ソシエタス・ヨーロピア ５，５−二置換２−イソオキサゾリンの製造方法
CN107652245A (zh) 2017-08-24 2018-02-02 郑州手性药物研究院有限公司 手性双苯噁唑酸乙酯化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4465133B2 (ja) 2001-02-08 2010-05-19 クミアイ化学工業株式会社 イソオキサゾリン誘導体及びこれを有効成分とする除草剤
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
EP2632906B1 (en) 2010-10-30 2016-04-06 Lupin Limited Oxazoline and isoxazoline derivatives as crac modulators
IL275272B (en) 2017-12-15 2022-08-01 Kumiai Chemical Industry Co Novel method for producing 5,5-disubstituted-4,5-dihydroisoxazole

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058290A1 (en) 1999-03-29 2000-10-05 Nippon Soda Co., Ltd. Process for the preparation of (e)-3-(1-propenyl)isoxazoline
JP2013512202A (ja) 2009-11-26 2013-04-11 ビーエーエスエフ ソシエタス・ヨーロピア ５，５−二置換２−イソオキサゾリンの製造方法
CN107652245A (zh) 2017-08-24 2018-02-02 郑州手性药物研究院有限公司 手性双苯噁唑酸乙酯化合物及其制备方法和应用

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
European Journal of Organic Chemistry，2002年，１２，１９１９－１９２４
Organic Letters，2013年，１５，３２１４－３２１７
新実験化学講座１４ 有機化合物の合成と反応ＩＩＩ，1978年，１３２５－１３２８

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US11753384B2 (en) 2023-09-12
BR112020021818A2 (pt) 2021-02-23
IL278229B2 (en) 2023-11-01
EP3789382A1 (en) 2021-03-10
IL278229B1 (en) 2023-07-01
CN112004805A (zh) 2020-11-27
EP3789382A4 (en) 2021-11-24
CN112004805B (zh) 2024-06-14
TW201945347A (zh) 2019-12-01
TWI810284B (zh) 2023-08-01
JPWO2019208643A1 (ja) 2021-05-13
WO2019208643A1 (ja) 2019-10-31
EP3789382B1 (en) 2023-07-05
US20210238150A1 (en) 2021-08-05
MX2020011267A (es) 2020-11-12
IL278229A (enExample) 2020-12-31

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