TWI808349B - 含有芳基烷基胺化合物之醫藥組合物 - Google Patents
含有芳基烷基胺化合物之醫藥組合物 Download PDFInfo
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- TWI808349B TWI808349B TW109133308A TW109133308A TWI808349B TW I808349 B TWI808349 B TW I808349B TW 109133308 A TW109133308 A TW 109133308A TW 109133308 A TW109133308 A TW 109133308A TW I808349 B TWI808349 B TW I808349B
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- DVQHRBFGRZHMSR-UHFFFAOYSA-N sodium methyl 2,2-dimethyl-4,6-dioxo-5-(N-prop-2-enoxy-C-propylcarbonimidoyl)cyclohexane-1-carboxylate Chemical compound [Na+].C=CCON=C(CCC)[C-]1C(=O)CC(C)(C)C(C(=O)OC)C1=O DVQHRBFGRZHMSR-UHFFFAOYSA-N 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229940126585 therapeutic drug Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 229960004394 topiramate Drugs 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/402—1-aryl substituted, e.g. piretanide
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/0012—Galenical forms characterised by the site of application
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- A61K9/2009—Inorganic compounds
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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- A—HUMAN NECESSITIES
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- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A—HUMAN NECESSITIES
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015-199694 | 2015-10-07 | ||
| JP2015199694 | 2015-10-07 | ||
| JP2016-197725 | 2016-10-06 | ||
| JP2016197725A JP6168673B2 (ja) | 2015-10-07 | 2016-10-06 | アリールアルキルアミン化合物含有医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW202110435A TW202110435A (zh) | 2021-03-16 |
| TWI808349B true TWI808349B (zh) | 2023-07-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| TW109133308A TWI808349B (zh) | 2015-10-07 | 2016-10-07 | 含有芳基烷基胺化合物之醫藥組合物 |
| TW105132660A TWI708603B (zh) | 2015-10-07 | 2016-10-07 | 含有芳基烷基胺化合物之醫藥組合物 |
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| Application Number | Title | Priority Date | Filing Date |
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| TW105132660A TWI708603B (zh) | 2015-10-07 | 2016-10-07 | 含有芳基烷基胺化合物之醫藥組合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10350194B2 (enExample) |
| EP (1) | EP3360551A4 (enExample) |
| JP (2) | JP6168673B2 (enExample) |
| KR (1) | KR102000897B1 (enExample) |
| CN (1) | CN108135883B (enExample) |
| TW (2) | TWI808349B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100800708B1 (ko) * | 2001-09-27 | 2008-02-01 | 삼성전자주식회사 | 키 텔레폰 시스템의 포트 상태 진단 방법 |
| CN108379588B (zh) * | 2018-03-05 | 2024-07-02 | 合肥合源药业有限公司 | 托吡酯组合物 |
| WO2020111089A1 (ja) * | 2018-11-27 | 2020-06-04 | 協和キリン株式会社 | 医薬組成物 |
| EP4029867A1 (en) * | 2021-01-13 | 2022-07-20 | Alpha Cognition Inc. | Solid forms of galantamine benzoate gluconate |
| CN115006363A (zh) * | 2022-06-23 | 2022-09-06 | 上海信谊万象药业股份有限公司 | 一种牡蛎碳酸钙咀嚼片及其制备方法 |
| JP2024023047A (ja) * | 2022-08-08 | 2024-02-21 | 日医工株式会社 | ビルダグリプチン含有医薬品 |
| CN115381094B (zh) * | 2022-08-18 | 2023-10-24 | 河南中大恒源生物科技股份有限公司 | 一种低臭味水溶性叶绿素铜及其制备方法与应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8362274B2 (en) * | 2004-05-28 | 2013-01-29 | Mitsubishi Tanabe Pharma Corporation | Arylalkylamine compound and process for preparing the same |
| WO2015034031A1 (ja) * | 2013-09-05 | 2015-03-12 | 田辺三菱製薬株式会社 | 新規な結晶性アリールアルキルアミン化合物およびその製造方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4880457A (enExample) | 1972-01-31 | 1973-10-27 | ||
| JPS5547615A (en) * | 1978-09-29 | 1980-04-04 | Taiyo Yakuhin Kogyo Kk | Stable solid drug of nifedipine |
| JP2914690B2 (ja) * | 1989-12-13 | 1999-07-05 | グレラン製薬株式会社 | 安定なビタミンｄ▲下３▼類含有製剤 |
| JP2001233766A (ja) * | 2000-11-15 | 2001-08-28 | Ohara Yakuhin Kogyo Kk | プラバスタチンナトリウムの錠剤 |
| JP2003104887A (ja) * | 2001-09-28 | 2003-04-09 | Maruko Seiyaku Kk | 光に安定なアラニジピン含有組成物 |
| ES2299710T3 (es) | 2002-08-02 | 2008-06-01 | Ratiopharm Gmbh | Preparacion farmaceutica que contiene un compuesto de bencimidazol mezclado con celulosa microcristalina y un metodo para su preparacion. |
| US20040122048A1 (en) * | 2002-10-11 | 2004-06-24 | Wyeth Holdings Corporation | Stabilized pharmaceutical composition containing basic excipients |
| JP4018664B2 (ja) * | 2003-04-30 | 2007-12-05 | 第一三共株式会社 | 安定化固形製剤 |
| GB0316206D0 (en) | 2003-07-10 | 2003-08-13 | Glaxo Group Ltd | Pharmaceutical formulation |
| TWI346114B (en) | 2003-09-29 | 2011-08-01 | Method for stabilization of diarylvinylene compounds | |
| JP2005154431A (ja) * | 2003-11-07 | 2005-06-16 | Takeda Chem Ind Ltd | 固形製剤 |
| WO2005044223A1 (en) | 2003-11-07 | 2005-05-19 | Takeda Pharmaceutical Company Limited | Chewable tablet |
| JP4783573B2 (ja) * | 2004-02-20 | 2011-09-28 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ワルファリンカリウム含有医薬組成物とその製造方法 |
| MXPA06012566A (es) * | 2004-04-30 | 2007-05-09 | Bkg Pharma Aps | Tratamiento de enfermedades infecciosas. |
| JP2007032370A (ja) * | 2005-07-25 | 2007-02-08 | Aisin Seiki Co Ltd | 電動ポンプ |
| EP1828098A1 (en) * | 2005-11-22 | 2007-09-05 | Teva Pharmaceutical Industries Ltd | Crystal forms of cinacalcet hci and processes for their preparation |
| SI1880718T1 (sl) * | 2006-07-10 | 2011-11-30 | Pfleger R Chem Fab | Farmacevtski pripravki za oralno dajanje z nadzorovanim sproščanjem zdravila v majhne intestinke kolone in postopek njihove priprave |
| GB0724478D0 (en) | 2007-12-14 | 2008-01-30 | Karobio Ab | Pharmaceutical compositions |
| WO2010067204A1 (en) * | 2008-12-08 | 2010-06-17 | Actavis Group Ptc Ehf | Highly pure cinacalcet or a pharmaceutically acceptable salt thereof |
| WO2010087462A1 (ja) * | 2009-01-29 | 2010-08-05 | 大日本住友製薬株式会社 | 内核を有する口腔内崩壊錠 |
| WO2011082980A2 (de) | 2009-12-16 | 2011-07-14 | Basf Se | Filmüberzugsmittel basierend auf polyvinylalkohol-polyether-pfropfcopolymeren- polyvinylalkohol-kombinationen mit verbesserter feuchtigkeitsbarrierewirkung |
| JP6133009B2 (ja) | 2010-08-11 | 2017-05-24 | 協和発酵キリン株式会社 | トピラマート顆粒 |
-
2016
- 2016-10-06 JP JP2016197725A patent/JP6168673B2/ja active Active
- 2016-10-07 TW TW109133308A patent/TWI808349B/zh active
- 2016-10-07 CN CN201680058580.7A patent/CN108135883B/zh active Active
- 2016-10-07 TW TW105132660A patent/TWI708603B/zh active
- 2016-10-07 US US15/766,426 patent/US10350194B2/en active Active
- 2016-10-07 KR KR1020187012497A patent/KR102000897B1/ko active Active
- 2016-10-07 EP EP16853772.8A patent/EP3360551A4/en not_active Withdrawn
- 2016-10-21 JP JP2016207285A patent/JP2017071605A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8362274B2 (en) * | 2004-05-28 | 2013-01-29 | Mitsubishi Tanabe Pharma Corporation | Arylalkylamine compound and process for preparing the same |
| WO2015034031A1 (ja) * | 2013-09-05 | 2015-03-12 | 田辺三菱製薬株式会社 | 新規な結晶性アリールアルキルアミン化合物およびその製造方法 |
Non-Patent Citations (2)
| Title |
|---|
| 期刊 Gaur, Praveen Kumar, et al. Film coating technology: past, present and future 1.1 3. Journal of Pharmaceutical Sciences and Pharmacology 2014 57-67;網路文獻 Kollicoat Grades Functional Polymers for the Pharmaceutical Industry .無 2007 .無 * |
| 網路文獻 Kollicoat Grades Functional Polymers for the Pharmaceutical Industry .無 2007 .無 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3360551A4 (en) | 2019-07-31 |
| JP6168673B2 (ja) | 2017-07-26 |
| TW202110435A (zh) | 2021-03-16 |
| US20180296526A1 (en) | 2018-10-18 |
| EP3360551A1 (en) | 2018-08-15 |
| US10350194B2 (en) | 2019-07-16 |
| JP2017071605A (ja) | 2017-04-13 |
| CN108135883B (zh) | 2021-09-14 |
| TWI708603B (zh) | 2020-11-01 |
| TW201717937A (zh) | 2017-06-01 |
| CN108135883A (zh) | 2018-06-08 |
| KR102000897B1 (ko) | 2019-07-16 |
| JP2017071599A (ja) | 2017-04-13 |
| KR20180054870A (ko) | 2018-05-24 |
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