TWI773647B - 新穎pd-1免疫調控劑 - Google Patents

新穎pd-1免疫調控劑 Download PDF

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TWI773647B
TWI773647B TW105119709A TW105119709A TWI773647B TW I773647 B TWI773647 B TW I773647B TW 105119709 A TW105119709 A TW 105119709A TW 105119709 A TW105119709 A TW 105119709A TW I773647 B TWI773647 B TW I773647B
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seq
cells
antigen
amino acid
binding protein
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TW105119709A
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TW201718648A (zh
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雷尼爾Ｊ 布蘭特詹恩斯
霍里 珍恩 傑克森
成 劉
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史隆凱特林紀念癌症中心
美商尤里卡醫療公司
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TW105119709A 2015-06-23 2016-06-23 新穎pd-1免疫調控劑 TWI773647B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562183297P 2015-06-23 2015-06-23
US62/183,297 2015-06-23
US201562266398P 2015-12-11 2015-12-11
US62/266,398 2015-12-11

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TW201718648A TW201718648A (zh) 2017-06-01
TWI773647B true TWI773647B (zh) 2022-08-11

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US (1) US11136392B2 (https=)
EP (1) EP3313883B1 (https=)
JP (2) JP6974311B2 (https=)
KR (1) KR20180019725A (https=)
CN (2) CN108337890B (https=)
AU (1) AU2016281641B2 (https=)
CA (1) CA3006224A1 (https=)
HK (1) HK1254803A1 (https=)
IL (1) IL256463A (https=)
TW (1) TWI773647B (https=)
WO (1) WO2016210129A1 (https=)

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CN107995913B (zh) 2015-05-18 2022-02-11 T细胞受体治疗公司 使用融合蛋白对tcr重编程的组合物和方法
FI3909972T3 (fi) 2015-06-19 2024-05-03 Sebastian Kobold Pd1-cd28-fuusioproteiineja ja niiden käyttö lääkkeessä
HK1254803A1 (zh) * 2015-06-23 2019-07-26 Memorial Sloan Kettering Cancer Center 新型pd -1的免疫调节剂
CN114591433A (zh) 2015-07-13 2022-06-07 西托姆克斯治疗公司 抗pd-1抗体、可活化抗pd-1抗体及其使用方法
CN114605548A (zh) 2015-09-01 2022-06-10 艾吉纳斯公司 抗-pd-1抗体及其使用方法
EA201890790A1 (ru) 2015-09-29 2018-10-31 Селджин Корпорейшн Связывающие pd-1 белки и способы их применения
NZ739090A (en) 2015-10-02 2025-06-27 Hoffmann La Roche Bispecific antibodies specific for pd1 and tim3
EP3370768B9 (en) 2015-11-03 2022-03-16 Janssen Biotech, Inc. Antibodies specifically binding pd-1 and their uses
WO2017133175A1 (en) * 2016-02-04 2017-08-10 Nanjing Legend Biotech Co., Ltd. Engineered mammalian cells for cancer therapy
US11549099B2 (en) 2016-03-23 2023-01-10 Novartis Ag Cell secreted minibodies and uses thereof
EP3443001B1 (en) 2016-04-11 2025-04-30 Obsidian Therapeutics, Inc. REGULATED BIOCIRCUIT SYSTEMS
EP3515943A4 (en) 2016-09-19 2020-05-06 Celgene Corporation METHODS OF TREATING VITILIGO WITH PD-1 BINDING PROTEINS
BR112019004733A2 (pt) 2016-09-19 2019-05-28 Celgene Corp métodos de tratamento de distúrbios imunes usando proteínas de ligação a pd-1
US11851491B2 (en) 2016-11-22 2023-12-26 TCR2 Therapeutics Inc. Compositions and methods for TCR reprogramming using fusion proteins
JP7106538B2 (ja) 2016-12-07 2022-07-26 アジェナス インコーポレイテッド 抗体およびその使用方法
JP6430682B2 (ja) * 2016-12-19 2018-11-28 昭和電工株式会社 レドックスフロー電池の運転方法
BR112019018915A2 (pt) 2017-03-15 2020-04-14 Pandion Therapeutics Inc imunotolerância direcionada
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