TWI662268B - 光學測量器 - Google Patents
光學測量器 Download PDFInfo
- Publication number
- TWI662268B TWI662268B TW105125313A TW105125313A TWI662268B TW I662268 B TWI662268 B TW I662268B TW 105125313 A TW105125313 A TW 105125313A TW 105125313 A TW105125313 A TW 105125313A TW I662268 B TWI662268 B TW I662268B
- Authority
- TW
- Taiwan
- Prior art keywords
- light
- light guide
- measuring device
- guide path
- optical measuring
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 68
- 238000005259 measurement Methods 0.000 claims abstract description 60
- 238000001514 detection method Methods 0.000 claims abstract description 18
- 230000031700 light absorption Effects 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims abstract description 11
- 230000015572 biosynthetic process Effects 0.000 claims description 9
- 229920001971 elastomer Polymers 0.000 claims description 6
- 239000000806 elastomer Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- 229920002050 silicone resin Polymers 0.000 claims description 4
- 239000011358 absorbing material Substances 0.000 claims description 3
- 239000000523 sample Substances 0.000 description 63
- 238000002835 absorbance Methods 0.000 description 12
- 239000013076 target substance Substances 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 4
- 238000003752 polymerase chain reaction Methods 0.000 description 3
- AFYNADDZULBEJA-UHFFFAOYSA-N bicinchoninic acid Chemical compound C1=CC=CC2=NC(C=3C=C(C4=CC=CC=C4N=3)C(=O)O)=CC(C(O)=O)=C21 AFYNADDZULBEJA-UHFFFAOYSA-N 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 238000012123 point-of-care testing Methods 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- -1 polydimethylsiloxane Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000009010 Bradford assay Methods 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 239000002041 carbon nanotube Substances 0.000 description 1
- 229910021393 carbon nanotube Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920005668 polycarbonate resin Polymers 0.000 description 1
- 239000004431 polycarbonate resin Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000013074 reference sample Substances 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/255—Details, e.g. use of specially adapted sources, lighting or optical systems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/123—Flexible; Elastomeric
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0332—Cuvette constructions with temperature control
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/022—Casings
- G01N2201/0221—Portable; cableless; compact; hand-held
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/064—Stray light conditioning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/08—Optical fibres; light guides
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015187762A JP6433398B2 (ja) | 2015-09-25 | 2015-09-25 | 光学測定器 |
| JP2015-187762 | 2015-09-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201721126A TW201721126A (zh) | 2017-06-16 |
| TWI662268B true TWI662268B (zh) | 2019-06-11 |
Family
ID=58386137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW105125313A TWI662268B (zh) | 2015-09-25 | 2016-08-09 | 光學測量器 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10809185B2 (https=) |
| JP (1) | JP6433398B2 (https=) |
| CN (1) | CN108139324B (https=) |
| TW (1) | TWI662268B (https=) |
| WO (1) | WO2017051638A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6924439B2 (ja) * | 2017-07-04 | 2021-08-25 | 国立大学法人九州大学 | 光測定装置、導光部材及び光測定方法 |
| WO2019009209A1 (ja) * | 2017-07-04 | 2019-01-10 | 国立大学法人九州大学 | 光測定装置、導光部材及び光測定方法 |
| CN112437877A (zh) * | 2018-09-11 | 2021-03-02 | 优志旺电机株式会社 | 酶标仪 |
| CN111307678A (zh) * | 2019-12-05 | 2020-06-19 | 怀光智能科技（武汉）有限公司 | 一种细胞悬浮液浓度测量及配液装置和工作方法 |
| KR102821335B1 (ko) * | 2019-12-16 | 2025-06-13 | 주식회사 코사이언스 | 유전체 분자 진단용 휴대용 램프 ｐｃｒ 장치 |
| TWI728885B (zh) * | 2020-07-30 | 2021-05-21 | 思創影像科技股份有限公司 | 導光模組與應用此導光模組之生物檢測設備 |
| JP7425428B2 (ja) * | 2022-07-05 | 2024-01-31 | 国立大学法人 熊本大学 | 光学測定器用サンプルホルダおよび光学測定器 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006300741A (ja) * | 2005-04-21 | 2006-11-02 | Rohm Co Ltd | 光学測定用マイクロ流路及びマイクロ流体チップ |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4609991A (en) * | 1983-07-19 | 1986-09-02 | The United States Of America As Represented By The Department Of Health And Human Services | Automated system for determining the molecular weight and/or concentration of macromolecules via sedimentation equilibrium |
| JP3994143B2 (ja) * | 1995-11-21 | 2007-10-17 | エヌアイアール ダイアグナスティック インク． | 血液分析器のための検体の迅速な分光光度法の予備検査鑑別方法及び装置 |
| JP3688068B2 (ja) * | 1996-08-29 | 2005-08-24 | シスメックス株式会社 | 液体試料測定装置 |
| US6992759B2 (en) * | 2002-10-21 | 2006-01-31 | Nippon Shokubai Co., Ltd. | Sample holder for spectrum measurement and spectrophotometer |
| CN2679854Y (zh) * | 2004-03-02 | 2005-02-16 | 肖剑鸣 | 微型通道光子倍增管 |
| US7375815B2 (en) * | 2004-10-12 | 2008-05-20 | Agilent Technologies, Inc. | Optical devices, systems and method for producing a collimated light path |
| CN1865927A (zh) * | 2006-05-18 | 2006-11-22 | 中国科学院安徽光学精密机械研究所 | 面污染源排放通量的被动差分吸收光谱测量方法与装置 |
| CN100381788C (zh) * | 2006-08-23 | 2008-04-16 | 北京航空航天大学 | 一种高精度低成本星光模拟器 |
| CN102859728A (zh) * | 2010-04-27 | 2013-01-02 | 信越化学工业株式会社 | 发光装置及发光装置的制造方法 |
| US8951472B2 (en) * | 2010-07-19 | 2015-02-10 | Andalyze, Inc. | Portable fluorimetric apparatus, method and system |
| CN102175690B (zh) * | 2011-01-24 | 2012-11-28 | 宁波大学 | 一种红外玻璃内部宏观缺陷检测装置 |
| CN104023834B (zh) * | 2011-05-04 | 2016-09-28 | 卢米耐克斯公司 | 用于集成的样品制备、反应和检测的设备与方法 |
| CN102954938B (zh) * | 2011-08-29 | 2014-08-27 | 中国科学院电子学研究所 | 基于微流控通道全反射集成光波导的吸收光度检测传感器 |
| KR101380368B1 (ko) * | 2012-09-18 | 2014-04-10 | 포항공과대학교 산학협력단 | 흡광 검출을 위한 흐름셀을 갖는 미세유체칩 및 이를 포함하는 흡광 검출 장치 |
| JP5947709B2 (ja) | 2012-12-27 | 2016-07-06 | 株式会社堀場製作所 | 分光分析方法及び分光分析装置 |
| US9488579B2 (en) * | 2013-01-22 | 2016-11-08 | Tecan Trading Ag | Optical measuring apparatus and method for the analysis of samples contained in liquid drops |
| CN103487144B (zh) * | 2013-08-29 | 2016-01-13 | 中国科学院长春光学精密机械与物理研究所 | 消杂光能力稳定的双光栅分光系统封装结构 |
| JP6331191B2 (ja) * | 2013-09-20 | 2018-05-30 | 国立大学法人九州大学 | 光測定装置、光測定方法、フィルタ部材及びフィルタ部材を生産する方法 |
| CN103762148B (zh) * | 2014-01-15 | 2016-03-02 | 山西长城微光器材股份有限公司 | 一种用于光电倍增管的微通道板 |
-
2015
- 2015-09-25 JP JP2015187762A patent/JP6433398B2/ja active Active
-
2016
- 2016-08-09 TW TW105125313A patent/TWI662268B/zh active
- 2016-08-17 CN CN201680055549.8A patent/CN108139324B/zh active Active
- 2016-08-17 WO PCT/JP2016/073992 patent/WO2017051638A1/ja not_active Ceased
-
2018
- 2018-03-22 US US15/933,053 patent/US10809185B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006300741A (ja) * | 2005-04-21 | 2006-11-02 | Rohm Co Ltd | 光学測定用マイクロ流路及びマイクロ流体チップ |
Also Published As
| Publication number | Publication date |
|---|---|
| US20180217052A1 (en) | 2018-08-02 |
| JP6433398B2 (ja) | 2018-12-05 |
| CN108139324B (zh) | 2021-02-02 |
| TW201721126A (zh) | 2017-06-16 |
| US10809185B2 (en) | 2020-10-20 |
| JP2017062184A (ja) | 2017-03-30 |
| WO2017051638A1 (ja) | 2017-03-30 |
| CN108139324A (zh) | 2018-06-08 |
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