TWI620816B - 植物衍生蛋白回收方法 - Google Patents

植物衍生蛋白回收方法 Download PDF

Info

Publication number
TWI620816B
TWI620816B TW101109798A TW101109798A TWI620816B TW I620816 B TWI620816 B TW I620816B TW 101109798 A TW101109798 A TW 101109798A TW 101109798 A TW101109798 A TW 101109798A TW I620816 B TWI620816 B TW I620816B
Authority
TW
Taiwan
Prior art keywords
protein
plant
cell wall
vlp
enzyme
Prior art date
Application number
TW101109798A
Other languages
English (en)
Chinese (zh)
Other versions
TW201245443A (en
Inventor
曼儂 考特爾
丹尼 帕克特
路易斯 菲力普 維西納
Original Assignee
苜蓿股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 苜蓿股份有限公司 filed Critical 苜蓿股份有限公司
Publication of TW201245443A publication Critical patent/TW201245443A/zh
Application granted granted Critical
Publication of TWI620816B publication Critical patent/TWI620816B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/145—Extraction; Separation; Purification by extraction or solubilisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW101109798A 2011-03-23 2012-03-22 植物衍生蛋白回收方法 TWI620816B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161466889P 2011-03-23 2011-03-23
US61/466,889 2011-03-23

Publications (2)

Publication Number Publication Date
TW201245443A TW201245443A (en) 2012-11-16
TWI620816B true TWI620816B (zh) 2018-04-11

Family

ID=46878587

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101109798A TWI620816B (zh) 2011-03-23 2012-03-22 植物衍生蛋白回收方法

Country Status (9)

Country Link
US (1) US9815873B2 (enExample)
EP (1) EP2688903B1 (enExample)
JP (1) JP6092840B2 (enExample)
CN (2) CN110041397A (enExample)
AU (2) AU2012231717A1 (enExample)
CA (1) CA2831000C (enExample)
ES (1) ES2682066T3 (enExample)
TW (1) TWI620816B (enExample)
WO (1) WO2012126123A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2579903C2 (ru) * 2009-09-22 2016-04-10 Медикаго Инк. Способ получения вирусоподобных частиц растений
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
US11390878B2 (en) 2011-09-30 2022-07-19 Medicago Inc. Increasing protein yield in plants
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
AU2014245779B2 (en) * 2013-03-28 2020-02-06 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
DK3092309T3 (da) 2014-01-10 2021-04-12 Medicago Inc Cpmv-forstærkerelementer
CN106460005B (zh) 2014-03-27 2020-01-03 莫迪卡戈公司 修饰的cpmv增强子元件
FR3054547B1 (fr) * 2016-07-29 2020-06-05 Angany Inc. Particules pseudo-virales et leurs utilisations
CN110483616B (zh) * 2019-07-31 2021-06-04 中国农业科学院农产品加工研究所 从感染病原菌的植物组织中分离病原菌分泌的质外体效应蛋白的方法
EP3808854A1 (de) * 2019-10-17 2021-04-21 eleva GmbH Verfahren zur gewinnung von material von pflanzenzelloberflächen
CN116194461A (zh) * 2020-08-05 2023-05-30 电化株式会社 目标蛋白质的回收方法及制造方法
TWI886721B (zh) * 2023-12-28 2025-06-11 財團法人工業技術研究院 植物的破壁萃取方法
JP7745040B1 (ja) * 2024-06-21 2025-09-26 デンカ株式会社 目的タンパク質の回収方法及び製造方法

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
JPS62501263A (ja) 1984-11-29 1987-05-21 スクリツプス　クリニツク　アンド　リサ−チ　フアウンデ−シヨン 脱グリコシル化ウイルス糖タンパク質に関連するポリペプチド類および抗体
US6846968B1 (en) * 1988-02-26 2005-01-25 Large Scale Biology Corporation Production of lysosomal enzymes in plants by transient expression
US5232833A (en) 1988-09-14 1993-08-03 Stressgen Biotechnologies Corporation Accumulation of heat shock proteins for evaluating biological damage due to chronic exposure of an organism to sublethal levels of pollutants
US6403865B1 (en) 1990-08-24 2002-06-11 Syngenta Investment Corp. Method of producing transgenic maize using direct transformation of commercially important genotypes
ATE142883T1 (de) 1991-03-28 1996-10-15 Rooperol Na Nv Zusammensetzungen von phytosterolen mit phytosterolinen als immunmodulatoren
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US6326470B1 (en) 1997-04-15 2001-12-04 The Penn State Research Foundation Enhancement of accessibility of cellulose by expansins
US5762939A (en) 1993-09-13 1998-06-09 Mg-Pmc, Llc Method for producing influenza hemagglutinin multivalent vaccines using baculovirus
AU6504796A (en) 1995-07-20 1997-02-18 Washington State University Research Foundation Production of secreted foreign polypeptides in plant cell culture
US5929304A (en) * 1995-09-14 1999-07-27 Croptech Development Corporation Production of lysosomal enzymes in plant-based expression systems
US20010006950A1 (en) 1998-02-11 2001-07-05 Juha Punnonen Genetic vaccine vector engineering
US6489537B1 (en) 1998-08-07 2002-12-03 The Trustees Of The University Of Pennsylvania Phytochelatin synthases and uses therefor
EP1104479B1 (en) * 1998-08-11 2006-10-18 Biosource Technologies, Inc. Method for recovering proteins from the interstitial fluid of plant tissues
AU2594300A (en) 1998-12-23 2000-07-12 Samuel Roberts Noble Foundation, Inc., The Plant transformation process
FR2791358B1 (fr) 1999-03-22 2003-05-16 Meristem Therapeutics Promoteurs chimeriques d'expression, cassettes d'expression, plasmides, vecteurs, plantes et semences transgeniques les contenant et leurs methodes d'obtention
CA2370638A1 (en) 1999-04-21 2000-10-26 Igor Kardailsky Plant transformation process
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
CA2435000C (en) 2001-01-18 2014-03-25 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Oligomeric complexes of chimeric proteins with enhanced immunogenic potential
DE10143205A1 (de) * 2001-09-04 2003-03-20 Icon Genetics Ag Verfahren zur Proteinproduktion in Pflanzen
AU2002324973A1 (en) 2001-09-14 2003-04-01 Fraunhofer-Gesellschaft Zur Forderung Der Angewandandten Forschung E.V. Immunoglobulin having particular framework scaffold and methods of making and using
US7226774B2 (en) 2002-02-13 2007-06-05 Wisconsin Alumni Research Foundation Signal for packaging of influenza virus vectors
AU2003213060A1 (en) 2002-02-14 2003-09-04 Novavax, Inc. Optimization of gene sequences of chimeric virus-like particles for expression in insect cells
AU2003219402B2 (en) 2002-03-19 2008-05-08 Stichting Dienst Landbouwkundig Onderzoek GnTIII (UDP-n-acethylglucosamine:beta-D mannoside beta (1,4)-N-acethylglucosaminy ltransferase III) expression in plants
NZ543348A (en) 2003-05-05 2008-08-29 Thompson Boyce Plant Res Vectors and cells for preparing immunoprotective compositions derived from transgenic plants
US20040268442A1 (en) 2003-05-05 2004-12-30 Dow Agrosciences Llc Stable immunoprophylactic and therapeutic compositions derived from transgenic plant cells and methods for production
CA2529647C (en) 2003-06-16 2013-08-13 Medimmune Vaccines, Inc. Influenza hemagglutinin and neuraminidase variants
US8592197B2 (en) 2003-07-11 2013-11-26 Novavax, Inc. Functional influenza virus-like particles (VLPs)
US7901691B2 (en) 2004-08-13 2011-03-08 Council Of Scientific And Indistrial Research Chimeric G protein based rabies vaccine
PT2374892T (pt) 2005-04-29 2018-03-29 Univ Cape Town Expressão de proteínas virais em plantas
CN101227920A (zh) 2005-07-19 2008-07-23 陶氏环球技术公司 重组流感疫苗
US7871626B2 (en) 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
AU2006304640B2 (en) 2005-10-18 2012-10-11 Novavax, Inc. Functional influenza virus like particles (VLPs)
JP5215865B2 (ja) 2005-11-22 2013-06-19 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド ノロウイルス抗原およびサポウイルス抗原
CA2642054C (en) 2006-02-13 2017-11-21 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
US20070250003A1 (en) 2006-04-03 2007-10-25 Bare Rex O Fluid activated retractable safety syringe
KR20080109094A (ko) 2006-04-21 2008-12-16 다우 아그로사이언시즈 엘엘씨 조류 인플루엔자 백신 및 이용방법
WO2007130327A2 (en) 2006-05-01 2007-11-15 Technovax, Inc. Influenza virus-like particle (vlp) compositions
DK2023952T3 (en) 2006-05-18 2015-10-19 Epimmune Inc Induction of immune responses to influenza virus using polypeptide and nucleic acid compositions
WO2007135480A1 (en) 2006-05-22 2007-11-29 Plant Bioscience Limited Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants
US20070286873A1 (en) 2006-05-23 2007-12-13 Williams John V Recombinant Influenza H5 Hemagluttinin Protein And Nucleic Acid Coding Therefor
MX2008015770A (es) 2006-07-13 2009-01-07 Sca Hygiene Prod Ab Una costura que une al menos dos materiales de red o trama.
EP2120762A1 (en) 2007-01-17 2009-11-25 Lerner Medical Devices, Inc. Fiber optic phototherapy device
US7730950B2 (en) 2007-01-19 2010-06-08 Halliburton Energy Services, Inc. Methods for treating intervals of a subterranean formation having variable permeability
BRPI0812538B1 (pt) 2007-06-15 2021-03-16 Medicago Inc. processo para a síntese de uma proteína de interesse com fucosilação e xilosilação reduzidas, ácido nucleico, e proteína híbrida gnt1-galt
KR100964462B1 (ko) 2007-07-10 2010-06-16 성균관대학교산학협력단 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
CA2696764A1 (en) 2007-08-20 2009-02-26 Fraunhofer Usa, Inc. Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods
NZ587108A (en) 2007-11-27 2013-04-26 Medicago Inc Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin
EP2235165A1 (en) * 2007-12-21 2010-10-06 Cytos Biotechnology AG Process for clarifying cell homogenates
CN101909454A (zh) 2007-12-28 2010-12-08 荷兰联合利华有限公司 从茶回收香味化合物的方法
US8799801B2 (en) 2008-01-16 2014-08-05 Qualcomm Incorporated Interactive ticker
KR101956910B1 (ko) 2008-01-21 2019-03-12 메디카고 인코포레이티드 헤마글루티닌을 발현하는 트랜스제닉 식물에서 생산된 재조합 인플루엔자 바이러스-유사 입자(ＶＬＰｓ)
EP2294202B1 (en) 2008-07-08 2015-05-20 Medicago Inc. Soluble recombinant influenza antigens
CN101626276A (zh) 2008-07-10 2010-01-13 华为技术有限公司 广告替换方法、装置及系统
JP5813505B2 (ja) 2008-07-18 2015-11-17 メディカゴ インコーポレイテッド 新規インフルエンザウイルス免疫エピトープ
US8513397B2 (en) 2008-08-27 2013-08-20 The Arizona Board Of Regents For And On Behalf Of Arizona State University DNA replicon system for high-level rapid production of vaccines and monoclonal antibody therapeutics in plants
US20100167376A1 (en) 2008-10-06 2010-07-01 Genvault Corporation Methods for providing cellular lysates from cell wall-containing samples
WO2010077712A1 (en) 2008-12-09 2010-07-08 Novavax, Inc. Bovine respiratory syncytial virus virus-like particle (vlps)
CN102365295A (zh) 2009-01-30 2012-02-29 阿德利夫股份有限公司 构象动力肽
PL2440183T3 (pl) 2009-06-10 2019-01-31 Arbutus Biopharma Corporation Ulepszona formulacja lipidowa
PT2440231T (pt) 2009-06-10 2020-01-08 Nono Inc Co-administração de um agente ligado a um peptido de internalização tat com um inibidor de desgranulação de mastócitos
JP5871796B2 (ja) 2009-06-24 2016-03-01 メディカゴ インコーポレイテッド ヘマグルチニンを含むキメラインフルエンザウイルス様粒子
RU2579903C2 (ru) 2009-09-22 2016-04-10 Медикаго Инк. Способ получения вирусоподобных частиц растений
CA2817005C (en) 2010-11-05 2018-09-11 Novavax Inc. Rabies glycoprotein virus-like particles (vlps)
TWI526539B (zh) 2010-12-22 2016-03-21 苜蓿股份有限公司 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Cosgrove DJ, "Loosening of plant cell walls by expansins", Nature, vol.407, p.321-326, 2000/09/21
Fischer R et al., "Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture", Journal of Immunological Methods, vol.226, p.1-10, 1999/06
Fischer R et al., "Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture", Journal of Immunological Methods, vol.226, p.1-10, 1999/06 Hellwig S et al., "Plant cell cultures for the production of recombinant proteins", Nature Biotechnology, vol.22, no.11, p.1415-1422, 2004/11/04 Cosgrove DJ, "Loosening of plant cell walls by expansins", Nature, vol.407, p.321-326, 2000/09/21 Low D et al., "Future of antibody purification", Journal of Chromatography B, vol.848, p.48-63, 2006/11/28 *
Hellwig S et al., "Plant cell cultures for the production of recombinant proteins", Nature Biotechnology, vol.22, no.11, p.1415-1422, 2004/11/04
Low D et al., "Future of antibody purification", Journal of Chromatography B, vol.848, p.48-63, 2006/11/28

Also Published As

Publication number Publication date
US20140024104A1 (en) 2014-01-23
CN103502261A (zh) 2014-01-08
AU2017202473B2 (en) 2018-12-20
JP6092840B2 (ja) 2017-03-08
WO2012126123A1 (en) 2012-09-27
WO2012126123A8 (en) 2012-12-20
ES2682066T3 (es) 2018-09-18
AU2017202473A1 (en) 2017-05-04
AU2012231717A1 (en) 2013-09-26
EP2688903B1 (en) 2018-06-27
JP2014510087A (ja) 2014-04-24
CA2831000A1 (en) 2012-09-27
EP2688903A4 (en) 2014-10-08
EP2688903A1 (en) 2014-01-29
US9815873B2 (en) 2017-11-14
CA2831000C (en) 2022-02-22
CN110041397A (zh) 2019-07-23
TW201245443A (en) 2012-11-16

Similar Documents

Publication Publication Date Title
TWI620816B (zh) 植物衍生蛋白回收方法
JP5551780B2 (ja) 植物由来のタンパク質を調製する方法
HK1259510B (en) Method of Preparing Plant-Derived Proteins METHOD OF PREPARING PLANT-DERIVED PROTEINS
HK1259510A1 (en) Method of preparing plant-derived proteins
HK1242372A1 (en) Method of preparing plant-derived vlps
HK1168115B (en) Method of preparing plant-derived proteins
HK1168115A (en) Method of preparing plant-derived proteins
HK1171787A (en) Method of preparing plant-derived vlps

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees