TWI619726B - 重組彈性蛋白酶蛋白質及其製備方法及用途 - Google Patents
重組彈性蛋白酶蛋白質及其製備方法及用途 Download PDFInfo
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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| US12/327,809 US8501449B2 (en) | 2007-12-04 | 2008-12-03 | Recombinant elastase proteins and methods of manufacturing and use thereof |
| US12/327,809 | 2008-12-03 |
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| TW097147270A TWI577385B (zh) | 2007-12-04 | 2008-12-04 | 重組彈性蛋白酶蛋白質及其製備方法及用途 |
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| US8501449B2 (en) * | 2007-12-04 | 2013-08-06 | Proteon Therapeutics, Inc. | Recombinant elastase proteins and methods of manufacturing and use thereof |
| CN102250863B (zh) * | 2011-04-29 | 2012-12-05 | 天津金斯坦生物科技有限公司 | 基因重组人中性粒细胞弹性蛋白酶及其制备方法和该弹性蛋白酶的医药用途 |
| US10202630B2 (en) * | 2013-03-15 | 2019-02-12 | Alderbio Holdings Llc | Temperature shift for high yield expression of polypeptides in yeast and other transformed cells |
| WO2014145650A1 (en) | 2013-03-15 | 2014-09-18 | Alder Biopharmaceuticals, Inc. | Temperature shift for high yield expression of polypeptides in yeast and other transformed cells |
| KR20250121449A (ko) * | 2017-03-10 | 2025-08-12 | 볼트 쓰레즈, 인크. | 재조합 단백질을 고분비 수율로 생산하기 위한 조성물 및 방법 |
| US20210299234A1 (en) * | 2017-06-15 | 2021-09-30 | The University Of Chicago | Methods and compositions for treating cancer |
| US20230002510A1 (en) * | 2019-11-26 | 2023-01-05 | Children's Hospital Medical Center | Cela-1 inhibition for treatment of lung disease |
| US20230074785A1 (en) * | 2020-01-14 | 2023-03-09 | Basf Se | Method For Producing Recombinant Protein In Yeast Cells |
| US20230365958A1 (en) * | 2020-08-18 | 2023-11-16 | Onchilles Pharma, Inc. | Modified porcine pancreatic elastase proteins |
| AU2021329330A1 (en) * | 2020-08-18 | 2023-02-02 | Onchilles Pharma, Inc. | Modified serine protease proproteins |
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| TWI577385B (zh) * | 2007-12-04 | 2017-04-11 | 普堤昂治療有限公司 | 重組彈性蛋白酶蛋白質及其製備方法及用途 |
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