TWI610691B - 含酸型羧甲基纖維素之崩壞性粒子組成物之製造方法、該組成物及含該組成物之口腔內崩壞錠劑 - Google Patents
含酸型羧甲基纖維素之崩壞性粒子組成物之製造方法、該組成物及含該組成物之口腔內崩壞錠劑 Download PDFInfo
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- TWI610691B TWI610691B TW102111387A TW102111387A TWI610691B TW I610691 B TWI610691 B TW I610691B TW 102111387 A TW102111387 A TW 102111387A TW 102111387 A TW102111387 A TW 102111387A TW I610691 B TWI610691 B TW I610691B
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- wet granulation
- granulation step
- particle composition
- component
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012075832 | 2012-03-29 | ||
| JP2012206896 | 2012-09-20 | ||
| JP2012206895 | 2012-09-20 | ||
| JP2012275942 | 2012-12-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201400145A TW201400145A (zh) | 2014-01-01 |
| TWI610691B true TWI610691B (zh) | 2018-01-11 |
Family
ID=49260166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW102111387A TWI610691B (zh) | 2012-03-29 | 2013-03-29 | 含酸型羧甲基纖維素之崩壞性粒子組成物之製造方法、該組成物及含該組成物之口腔內崩壞錠劑 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20150174075A2 (enExample) |
| EP (1) | EP2832350B1 (enExample) |
| JP (1) | JP5996633B2 (enExample) |
| KR (1) | KR101707938B1 (enExample) |
| CN (1) | CN104080443B (enExample) |
| IN (1) | IN2014DN07797A (enExample) |
| TW (1) | TWI610691B (enExample) |
| WO (1) | WO2013146917A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104080443B (zh) | 2012-03-29 | 2017-12-12 | 株式会社大赛璐 | 含酸式羧甲基纤维素的崩解性颗粒组合物的制法、及该组合物和含该组合物的口腔崩解片剂 |
| JP6230539B2 (ja) | 2012-09-20 | 2017-11-15 | 株式会社ダイセル | 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 |
| TWI673069B (zh) * | 2013-07-06 | 2019-10-01 | 日商大賽璐股份有限公司 | 超高速崩解錠劑及其製造方法 |
| US20160213619A1 (en) * | 2013-09-27 | 2016-07-28 | Daicel Corporation | Intraorally disintegrable tablet comprising disintegrable granular composition |
| JP6476122B2 (ja) * | 2013-09-27 | 2019-02-27 | 株式会社ダイセル | 二段階の湿式造粒工程で製造される崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 |
| JP2017036214A (ja) * | 2013-12-10 | 2017-02-16 | 株式会社ダイセル | 炭酸塩を含む口腔内崩壊錠剤用組成物及び口腔内崩壊錠剤 |
| US10828257B2 (en) | 2014-04-21 | 2020-11-10 | Daicel Corporation | Disintegrating particle composition including microfibrous cellulose |
| JP2017226600A (ja) * | 2014-10-16 | 2017-12-28 | 株式会社ダイセル | 超速崩壊錠剤 |
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- 2013-03-27 IN IN7797DEN2014 patent/IN2014DN07797A/en unknown
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|---|---|
| CN104080443A (zh) | 2014-10-01 |
| EP2832350B1 (en) | 2019-07-17 |
| KR101707938B1 (ko) | 2017-02-17 |
| EP2832350A1 (en) | 2015-02-04 |
| EP2832350A4 (en) | 2015-11-18 |
| JP5996633B2 (ja) | 2016-09-21 |
| WO2013146917A1 (ja) | 2013-10-03 |
| JPWO2013146917A1 (ja) | 2015-12-14 |
| US20150045452A1 (en) | 2015-02-12 |
| KR20140144249A (ko) | 2014-12-18 |
| TW201400145A (zh) | 2014-01-01 |
| IN2014DN07797A (enExample) | 2015-05-15 |
| US20150174075A2 (en) | 2015-06-25 |
| US12059501B2 (en) | 2024-08-13 |
| US20200038332A1 (en) | 2020-02-06 |
| CN104080443B (zh) | 2017-12-12 |
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