IN2014DN07797A - - Google Patents

Info

Publication number
IN2014DN07797A
IN2014DN07797A IN7797DEN2014A IN2014DN07797A IN 2014DN07797 A IN2014DN07797 A IN 2014DN07797A IN 7797DEN2014 A IN7797DEN2014 A IN 7797DEN2014A IN 2014DN07797 A IN2014DN07797 A IN 2014DN07797A
Authority
IN
India
Prior art keywords
disintegrating
components
tablet
wet granulation
component
Prior art date
Application number
Inventor
Takahiro Hiramura
Kiyoshi Ikura
Sae Ishikawa
Tomohito Okabayashi
Naohiro Hashikawa
Tetsuro Morita
Kimiko Ikeda
Haruka WAKAYAMA
Original Assignee
Daicel Corp
Nichirin Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49260166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2014DN07797(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daicel Corp, Nichirin Chemical Ind filed Critical Daicel Corp
Publication of IN2014DN07797A publication Critical patent/IN2014DN07797A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

The purpose of the present application is to provide an orally disintegrating tablet having excellent tablet hardness and disintegrating performance a disintegrating particulate composition by which the orally disintegrating tablet is obtained with relatively low tablet compression force and which is able to impart excellent moldability a method for producing the same and the like. The present application pertains to: a method for producing a disintegrating particulate composition including the three components of a first disintegrating tablet component comprising acid type carboxymethylcellulose a second disintegrating tablet component and an excipient wherein the method includes a first wet granulation step for using any two components of the three components and a second wet granulation step for using the granulated material obtained in the first wet granulation step and the remaining one component of the three components; a production method further including crystalline cellulose as a fourth component; a production method comprising a third step for mixing crystalline cellulose into the granulated material obtained in the second wet granulation step; disintegrating particulate compositions obtained by these production methods; and the like.
IN7797DEN2014 2012-03-29 2013-03-27 IN2014DN07797A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2012075832 2012-03-29
JP2012206896 2012-09-20
JP2012206895 2012-09-20
JP2012275942 2012-12-18
PCT/JP2013/059083 WO2013146917A1 (en) 2012-03-29 2013-03-27 Method for producing disintegrating particulate composition comprising acid-type carboxymethylcellulose, disintegrating particulate composition comprising acid-type carboxymethylcellulose, and orally disintegrating tablet including disintegrating particulate composition comprising acid-type carboxymethylcellulose

Publications (1)

Publication Number Publication Date
IN2014DN07797A true IN2014DN07797A (en) 2015-05-15

Family

ID=49260166

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7797DEN2014 IN2014DN07797A (en) 2012-03-29 2013-03-27

Country Status (8)

Country Link
US (2) US20150174075A2 (en)
EP (1) EP2832350B1 (en)
JP (1) JP5996633B2 (en)
KR (1) KR101707938B1 (en)
CN (1) CN104080443B (en)
IN (1) IN2014DN07797A (en)
TW (1) TWI610691B (en)
WO (1) WO2013146917A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2832350B1 (en) 2012-03-29 2019-07-17 Daicel Corporation Method for producing disintegrating particulate composition comprising acid-type carboxymethylcellulose, disintegrating particulate composition comprising acid-type carboxymethylcellulose, and orally disintegrating tablet including disintegrating particulate composition comprising acid-type carboxymethylcellulose
KR102114487B1 (en) 2012-09-20 2020-05-22 주식회사 다이셀 Disintegrating particle composition containing acid-type carboxymethylcellulose and crystalline cellulose, and orally disintegrating tablet containing said composition
CN105517576A (en) * 2013-07-06 2016-04-20 株式会社大赛璐 Ultrafast-disintegrating tablet and method for manufacturing same
CN105555262A (en) * 2013-09-27 2016-05-04 株式会社大赛璐 Intraorally disintegrable tablet comprising disintegrable granular composition
WO2015046223A1 (en) * 2013-09-27 2015-04-02 株式会社ダイセル Disintegrating particle composition produced by two-stage wet granulation process, and intraorally disintegrating tablet containing same composition
JP2017036214A (en) * 2013-12-10 2017-02-16 株式会社ダイセル Composition, which contains carbonate, for intraorally disintegrating tablet, and intraorally disintegrating tablet
AU2015251692B2 (en) 2014-04-21 2019-12-19 Daicel Corporation Disintegrating particle composition including microfibrous cellulose
JP2017226600A (en) * 2014-10-16 2017-12-28 株式会社ダイセル Super fast disintegrating tablet
CA2968210A1 (en) 2014-11-24 2016-06-02 Daicel Corporation A disintegrative particulate composition comprising milled lactose or granulated lactose
WO2016098459A1 (en) * 2014-12-17 2016-06-23 株式会社ダイセル Delayed disintegrating particulate composition
WO2016103904A1 (en) * 2014-12-25 2016-06-30 株式会社ダイセル Very rapidly disintegrating tablet, and method for producing same
JP5897196B1 (en) * 2015-10-05 2016-03-30 大同化成工業株式会社 Compound granulated product containing sugar or sugar alcohol, swelling binder, disintegrant and superabsorbent excipient, and production method thereof
WO2018021265A1 (en) 2016-07-27 2018-02-01 沢井製薬株式会社 Additive composition for orally disintegrating tablet
JP6651638B2 (en) 2016-09-06 2020-02-19 沢井製薬株式会社 Orally disintegrating tablet additive composition
KR20210038603A (en) * 2018-07-25 2021-04-07 주식회사 다이셀 Disintegrative particle composition containing fibrous cellulose and no excipients
JP7360460B2 (en) * 2019-06-07 2023-10-12 あゆみ製薬株式会社 Orally disintegrating tablet and its manufacturing method

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US2851453A (en) * 1954-08-09 1958-09-09 Smith Kline French Lab Cellulose derivative product, compositions comprising the same and their preparation
JPH10182436A (en) 1996-10-31 1998-07-07 Takeda Chem Ind Ltd Solid medicinal preparation
JP2000273039A (en) 1999-01-20 2000-10-03 Taisho Pharmaceut Co Ltd Orally disintegrating composition
AU2001294192A1 (en) * 2000-10-06 2002-04-22 Takeda Chemical Industries Ltd. Solid preparations
JP4284017B2 (en) * 2000-10-06 2009-06-24 武田薬品工業株式会社 Solid preparation
JP4551627B2 (en) 2003-02-28 2010-09-29 東和薬品株式会社 Method for producing orally disintegrating tablets
WO2005013964A1 (en) 2003-08-08 2005-02-17 Ajinomoto Co., Inc. Pharmaceutical preparation containing nateglinide
KR20130016386A (en) * 2005-08-10 2013-02-14 시오노기세이야쿠가부시키가이샤 Orally disintegratable tablet
JP5123517B2 (en) 2005-11-14 2013-01-23 帝人ファーマ株式会社 Ambroxol oral disintegrating tablet
MX2009001711A (en) * 2006-11-17 2009-05-08 Supernus Pharmaceuticals Inc Sustained-release formulations of topiramate.
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JP2008285434A (en) 2007-05-16 2008-11-27 Taisho Pharm Ind Ltd Orally disintegrating tablets
EP2164462B1 (en) 2007-06-06 2017-05-31 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
KR101612137B1 (en) * 2008-02-13 2016-04-12 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Orally disintegrating tablets
EP2368544A4 (en) * 2008-11-25 2012-08-15 Mitsubishi Tanabe Pharma Corp RAPID ORAL DELETING TABLET, AND PROCESS FOR PRODUCING THE SAME
KR20120046766A (en) 2009-08-11 2012-05-10 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Tablet that disintegrates rapidly in the mouth and that contains two or more types of particles
JP5674666B2 (en) * 2009-08-11 2015-02-25 富士化学工業株式会社 Disintegrating particle composition and intraoral quick disintegrating tablet
US20110150989A1 (en) * 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
US9198861B2 (en) * 2009-12-22 2015-12-01 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
JP6073543B2 (en) 2010-07-08 2017-02-01 沢井製薬株式会社 Method for producing loratadine-containing orally disintegrating tablet
JP5630902B2 (en) * 2010-08-26 2014-11-26 沢井製薬株式会社 Method for producing orally disintegrating tablets containing zolpidem tartrate
JP6245677B2 (en) 2012-01-20 2017-12-13 ニプロ株式会社 Orally disintegrating tablets
EP2832350B1 (en) 2012-03-29 2019-07-17 Daicel Corporation Method for producing disintegrating particulate composition comprising acid-type carboxymethylcellulose, disintegrating particulate composition comprising acid-type carboxymethylcellulose, and orally disintegrating tablet including disintegrating particulate composition comprising acid-type carboxymethylcellulose
KR102114487B1 (en) 2012-09-20 2020-05-22 주식회사 다이셀 Disintegrating particle composition containing acid-type carboxymethylcellulose and crystalline cellulose, and orally disintegrating tablet containing said composition
WO2015046223A1 (en) * 2013-09-27 2015-04-02 株式会社ダイセル Disintegrating particle composition produced by two-stage wet granulation process, and intraorally disintegrating tablet containing same composition
CA2968210A1 (en) * 2014-11-24 2016-06-02 Daicel Corporation A disintegrative particulate composition comprising milled lactose or granulated lactose
TWI690333B (en) * 2015-06-29 2020-04-11 日商大賽璐股份有限公司 Manufacturing method of easy-to-take solid preparation (with nuclear ingot) and easy-to-take solid preparation

Also Published As

Publication number Publication date
EP2832350A1 (en) 2015-02-04
KR101707938B1 (en) 2017-02-17
JPWO2013146917A1 (en) 2015-12-14
TWI610691B (en) 2018-01-11
CN104080443A (en) 2014-10-01
TW201400145A (en) 2014-01-01
US12059501B2 (en) 2024-08-13
US20150174075A2 (en) 2015-06-25
EP2832350B1 (en) 2019-07-17
US20200038332A1 (en) 2020-02-06
WO2013146917A1 (en) 2013-10-03
KR20140144249A (en) 2014-12-18
CN104080443B (en) 2017-12-12
JP5996633B2 (en) 2016-09-21
US20150045452A1 (en) 2015-02-12
EP2832350A4 (en) 2015-11-18

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