TWI595009B - Identification of antibody manufacturing methods and labeling antibodies - Google Patents

Identification of antibody manufacturing methods and labeling antibodies Download PDF

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Publication number
TWI595009B
TWI595009B TW103103705A TW103103705A TWI595009B TW I595009 B TWI595009 B TW I595009B TW 103103705 A TW103103705 A TW 103103705A TW 103103705 A TW103103705 A TW 103103705A TW I595009 B TWI595009 B TW I595009B
Authority
TW
Taiwan
Prior art keywords
antibody
group
molecule
cerium oxide
thiol group
Prior art date
Application number
TW103103705A
Other languages
English (en)
Chinese (zh)
Other versions
TW201443082A (zh
Inventor
Nobumitsu Yamanaka
Hideki Aizawa
Michio Ohkubo
Kazutomi Miyoshi
Original Assignee
Furukawa Electric Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Furukawa Electric Co Ltd filed Critical Furukawa Electric Co Ltd
Publication of TW201443082A publication Critical patent/TW201443082A/zh
Application granted granted Critical
Publication of TWI595009B publication Critical patent/TWI595009B/zh

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Silicon Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
TW103103705A 2013-02-04 2014-01-29 Identification of antibody manufacturing methods and labeling antibodies TWI595009B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013019972A JP6026305B2 (ja) 2013-02-04 2013-02-04 標識抗体の製造方法

Publications (2)

Publication Number Publication Date
TW201443082A TW201443082A (zh) 2014-11-16
TWI595009B true TWI595009B (zh) 2017-08-11

Family

ID=51262336

Family Applications (1)

Application Number Title Priority Date Filing Date
TW103103705A TWI595009B (zh) 2013-02-04 2014-01-29 Identification of antibody manufacturing methods and labeling antibodies

Country Status (6)

Country Link
US (1) US10466234B2 (fr)
EP (1) EP2952895B1 (fr)
JP (1) JP6026305B2 (fr)
CN (1) CN104981693B (fr)
TW (1) TWI595009B (fr)
WO (1) WO2014119624A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015022914A1 (fr) * 2013-08-12 2015-02-19 古河電気工業株式会社 Particules de silice, chacune comportant à sa surface un groupement fonctionnel réactif, et procédé de production de celles-ci
KR20180057634A (ko) 2015-09-03 2018-05-30 벡톤 디킨슨 앤드 컴퍼니 라벨링된 생체분자를 제공하기 위한 방법 및 시스템
CN105445465A (zh) * 2015-11-16 2016-03-30 珠海国际旅行卫生保健中心 一种快速检测副溶血性弧菌的荧光纳米免疫层析试剂盒及制备方法
JP7171702B2 (ja) * 2018-03-23 2022-11-15 大塚製薬株式会社 標識化抗体分散液、ｓｐｆｓ用キット
JP7091129B2 (ja) * 2018-04-27 2022-06-27 キヤノン株式会社 粒子、及びその製造方法
WO2020148985A1 (fr) * 2019-01-18 2020-07-23 コニカミノルタ株式会社 Nanoparticules intégrées au phosphore pour la détection d'une substance cible

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
WO2006070582A1 (fr) * 2004-12-09 2006-07-06 Techno Network Shikoku. Co., Ltd. Procede de preparation d’une sphere de silice contenant une molecule marquee
WO2012147774A1 (fr) * 2011-04-26 2012-11-01 古河電気工業株式会社 Procédé d'obtention de nanoparticules de silice contenant des molécules fonctionnelles auxquelles sont liées de biomolécules

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991007087A1 (fr) * 1989-11-13 1991-05-30 Affymax Technologies N.V. Immobilisation adressable dans l'espace d'anti-ligands sur des surfaces
ES2258527T3 (es) 2000-05-05 2006-09-01 Bayer Technology Services Gmbh Nanoparticulas impurificadas como biomarcadores.
US8185209B2 (en) * 2003-01-03 2012-05-22 Board Of Trustees Operating Michigan State University Methods to extend vision to infrared wavelengths
EP1949108B1 (fr) * 2005-11-18 2013-09-25 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Cardiolipine modifiee et ses utilisations
JP5400297B2 (ja) 2005-12-27 2014-01-29 古河電気工業株式会社 蛍光ナノシリカ粒子、ナノ蛍光材料、それを用いたバイオチップ及びそのアッセイ法
JP4360652B2 (ja) * 2007-06-08 2009-11-11 古河電気工業株式会社 イムノクロマト法試薬用標識シリカナノ粒子、イムノクロマト法試薬、それを用いたイムノクロマト法用テストストリップ、及びイムノクロマト法用蛍光検出システム
EP2201374B1 (fr) 2007-08-30 2015-10-07 Trustees Of Tufts College Procédés pour déterminer la concentration d'un analyte dans une solution
US9265729B2 (en) * 2007-12-06 2016-02-23 The University Of Tokushima Nanofunctional silica particles and manufacturing method thereof
WO2009143720A1 (fr) 2008-05-27 2009-12-03 The Chinese University Of Hong Kong Nanoparticules, procédés de fabrication de celles-ci et marquage de cellules utilisant celles-ci
JP5203132B2 (ja) * 2008-10-21 2013-06-05 古河電気工業株式会社 架橋性官能基を粒子表面に有するシリカ粒子の製造方法、架橋性官能基を粒子表面に有するシリカ粒子、前記シリカ粒子のコロイド、前記シリカ粒子を用いた複合粒子、及び前記複合粒子の製造方法
JP5686096B2 (ja) * 2009-05-08 2015-03-18 コニカミノルタ株式会社 量子ドット内包シリカナノ粒子、その製造方法、およびそれを用いた生体物質標識剤
ES2702926T3 (es) * 2010-12-09 2019-03-06 Immunogen Inc Métodos para la preparación de agentes de reticulación cargados
JP2012198062A (ja) * 2011-03-18 2012-10-18 National Institute Of Advanced Industrial & Technology 基板表面に核酸を固定する方法及び核酸が固定された基板
JP2012233878A (ja) * 2011-04-22 2012-11-29 Sysmex Corp 被検物質の電気化学的検出方法
CN103534272B (zh) * 2011-05-09 2016-05-11 株式会社英仙蛋白质科学 能够特异性识别转铁蛋白受体的抗体
WO2015022914A1 (fr) * 2013-08-12 2015-02-19 古河電気工業株式会社 Particules de silice, chacune comportant à sa surface un groupement fonctionnel réactif, et procédé de production de celles-ci

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
WO2006070582A1 (fr) * 2004-12-09 2006-07-06 Techno Network Shikoku. Co., Ltd. Procede de preparation d’une sphere de silice contenant une molecule marquee
WO2012147774A1 (fr) * 2011-04-26 2012-11-01 古河電気工業株式会社 Procédé d'obtention de nanoparticules de silice contenant des molécules fonctionnelles auxquelles sont liées de biomolécules

Also Published As

Publication number Publication date
EP2952895A1 (fr) 2015-12-09
JP2014153057A (ja) 2014-08-25
US10466234B2 (en) 2019-11-05
EP2952895B1 (fr) 2018-01-10
CN104981693A (zh) 2015-10-14
CN104981693B (zh) 2017-05-31
US20150338395A1 (en) 2015-11-26
JP6026305B2 (ja) 2016-11-16
EP2952895A4 (fr) 2016-10-12
WO2014119624A1 (fr) 2014-08-07
TW201443082A (zh) 2014-11-16

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