TWI591174B - 非接觸式即時微型聚合酶連鎖反應之系統及其方法 - Google Patents
非接觸式即時微型聚合酶連鎖反應之系統及其方法 Download PDFInfo
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- TWI591174B TWI591174B TW100115011A TW100115011A TWI591174B TW I591174 B TWI591174 B TW I591174B TW 100115011 A TW100115011 A TW 100115011A TW 100115011 A TW100115011 A TW 100115011A TW I591174 B TWI591174 B TW I591174B
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- Prior art keywords
- wafer
- heater
- sample
- embedded metal
- pcr
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Links
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Classifications
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- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- B01L2200/02—Adapting objects or devices to another
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- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
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- B01L2200/147—Employing temperature sensors
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1816—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using induction heating
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Biotechnology (AREA)
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- Biophysics (AREA)
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- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1215CH2010 | 2010-04-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201144432A TW201144432A (en) | 2011-12-16 |
| TWI591174B true TWI591174B (zh) | 2017-07-11 |
Family
ID=44860952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW100115011A TWI591174B (zh) | 2010-04-30 | 2011-04-29 | 非接觸式即時微型聚合酶連鎖反應之系統及其方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9404151B2 (enExample) |
| EP (1) | EP2563513A4 (enExample) |
| JP (1) | JP6026996B2 (enExample) |
| KR (1) | KR20130092391A (enExample) |
| CN (1) | CN102939161B (enExample) |
| AR (1) | AR081288A1 (enExample) |
| BR (1) | BR112012027876A2 (enExample) |
| EA (1) | EA201291008A1 (enExample) |
| SG (1) | SG185045A1 (enExample) |
| TW (1) | TWI591174B (enExample) |
| WO (1) | WO2011135535A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618027B2 (en) | 2019-12-10 | 2023-04-04 | Wistron Corp. | Molecular diagnostics apparatus |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102604827B (zh) * | 2012-03-31 | 2014-01-29 | 中国科学院上海微系统与信息技术研究所 | 非接触式电导法实现pcr反应过程的实时检测系统和方法 |
| NZ719726A (en) * | 2013-10-15 | 2021-07-30 | Bio Molecular Systems Pty Ltd | Improved thermocycler |
| CN103645167A (zh) * | 2013-12-13 | 2014-03-19 | 苏州东胜兴业科学仪器有限公司 | 一种聚合酶链反应检测仪 |
| GB201520193D0 (en) * | 2015-11-16 | 2015-12-30 | Mast Group Ltd | Apparatus for conducting an assay |
| CN106047687B (zh) * | 2016-04-08 | 2018-05-18 | 芜湖达辉生物科技有限公司 | 核糖核酸链式聚合扩增反应检测装置及其进行dna浓度检测的方法 |
| EP3287190B1 (de) * | 2016-08-26 | 2020-07-01 | Aquila Biolabs GmbH | Verfahren zum überwachen eines zielprozessparameters |
| US20180136246A1 (en) * | 2016-11-15 | 2018-05-17 | Quidel Corporation | Device, instrument, and method for inductive heating of a sample for analyte detection |
| GB2556626A (en) * | 2016-11-16 | 2018-06-06 | Dublin Institute Of Tech | A microfluidic device |
| US10207241B2 (en) * | 2016-11-29 | 2019-02-19 | Kontak LLC | Inductively heated microchannel reactor |
| CN107051598B (zh) * | 2017-03-20 | 2019-12-06 | 上海交通大学 | Pcr微流控芯片和其制备与使用方法以及pcr设备 |
| CN109957506B (zh) | 2017-12-22 | 2022-04-01 | 克雷多生物医学私人有限公司 | 通过试剂容器以热对流进行定量聚合酶链式反应的装置 |
| TWI656211B (zh) * | 2017-12-22 | 2019-04-11 | 新加坡商元昌生技醫療私人股份有限公司 | 一種熱對流式聚合酶鏈式反應裝置 |
| CN108315252B (zh) * | 2018-03-30 | 2023-09-05 | 中国科学院天津工业生物技术研究所 | 一种光控芯片反应系统及方法 |
| US11555473B2 (en) | 2018-05-29 | 2023-01-17 | Kontak LLC | Dual bladder fuel tank |
| US11638331B2 (en) | 2018-05-29 | 2023-04-25 | Kontak LLC | Multi-frequency controllers for inductive heating and associated systems and methods |
| CN108998371A (zh) * | 2018-09-28 | 2018-12-14 | 北京金豪制药股份有限公司 | 一种低压磁感应加热的pcr控温装置 |
| CN111286459B (zh) * | 2020-02-28 | 2023-05-30 | 宁波胤瑞生物医学仪器有限责任公司 | 一种用于数字pcr芯片的油封装置 |
| CN112858864B (zh) * | 2021-01-18 | 2022-02-18 | 厦门大学 | 一种对led芯片进行非接触式光电检测的装置及方法 |
| EP4355900A4 (en) * | 2021-08-05 | 2024-08-21 | Hewlett-Packard Development Company, L.P. | POLYMERASE CHAIN REACTION TEST WELL COMPRISING RESISTIVE SHEET |
| CN114381363B (zh) * | 2021-12-28 | 2024-04-30 | 深圳市思坦科技有限公司 | Pcr快速检测系统制备方法及pcr快速检测系统 |
| KR102953379B1 (ko) * | 2022-06-10 | 2026-04-17 | 한국전자통신연구원 | Pcr 진단 장치 |
| CN116828641B (zh) * | 2023-06-21 | 2026-07-31 | 西安交通大学 | 一种微加热器及其制造方法 |
Family Cites Families (10)
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| JPS6017990B2 (ja) * | 1978-08-03 | 1985-05-08 | 三菱電機株式会社 | 焼成炉 |
| JPH0235053A (ja) * | 1988-07-25 | 1990-02-05 | Shigeo Tani | 大豆の不快臭発生防止方法及びその装置 |
| JPH074037B2 (ja) * | 1989-07-12 | 1995-01-18 | 巖 橋本 | マイクロホンヘッドの風防網組立治具および方法ならびに溶着装置 |
| US6833536B2 (en) * | 2002-05-22 | 2004-12-21 | Applera Corporation | Non-contact radiant heating and temperature sensing device for a chemical reaction chamber |
| GB0212764D0 (en) * | 2002-05-31 | 2002-07-10 | Deltadot Ltd | Direct PCR quantification |
| US20050158725A1 (en) * | 2002-09-24 | 2005-07-21 | Tetsuo Yukimasa | Method of amplifying nucleic acid by electromagnetic induction heating and reaction container and reaction device to be used therein |
| JP4705035B2 (ja) * | 2003-05-23 | 2011-06-22 | バイオ−ラッド ラボラトリーズ，インコーポレイティド | 反応培地の空間配列に対し局部化した温度制御 |
| US20060082768A1 (en) * | 2004-08-31 | 2006-04-20 | Wilson Denise M | Miniaturized fluorescence analysis system |
| US7629124B2 (en) * | 2006-06-30 | 2009-12-08 | Canon U.S. Life Sciences, Inc. | Real-time PCR in micro-channels |
| CL2008003007A1 (es) * | 2007-10-12 | 2009-10-02 | Bigtec Private Ltd | Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr). |
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2011
- 2011-04-28 CN CN201180021966.8A patent/CN102939161B/zh not_active Expired - Fee Related
- 2011-04-28 JP JP2013506801A patent/JP6026996B2/ja not_active Expired - Fee Related
- 2011-04-28 EA EA201291008A patent/EA201291008A1/ru unknown
- 2011-04-28 SG SG2012079307A patent/SG185045A1/en unknown
- 2011-04-28 EP EP11774523.2A patent/EP2563513A4/en not_active Withdrawn
- 2011-04-28 US US13/695,254 patent/US9404151B2/en active Active
- 2011-04-28 BR BR112012027876A patent/BR112012027876A2/pt not_active IP Right Cessation
- 2011-04-28 WO PCT/IB2011/051872 patent/WO2011135535A1/en not_active Ceased
- 2011-04-28 KR KR1020127029020A patent/KR20130092391A/ko not_active Ceased
- 2011-04-29 TW TW100115011A patent/TWI591174B/zh not_active IP Right Cessation
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618027B2 (en) | 2019-12-10 | 2023-04-04 | Wistron Corp. | Molecular diagnostics apparatus |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6026996B2 (ja) | 2016-11-16 |
| CN102939161A (zh) | 2013-02-20 |
| BR112012027876A2 (pt) | 2017-03-21 |
| EP2563513A4 (en) | 2013-12-04 |
| US20130101983A1 (en) | 2013-04-25 |
| CN102939161B (zh) | 2016-01-20 |
| AR081288A1 (es) | 2012-08-01 |
| JP2013524832A (ja) | 2013-06-20 |
| KR20130092391A (ko) | 2013-08-20 |
| WO2011135535A1 (en) | 2011-11-03 |
| US9404151B2 (en) | 2016-08-02 |
| SG185045A1 (en) | 2012-11-29 |
| EA201291008A1 (ru) | 2013-05-30 |
| EP2563513A1 (en) | 2013-03-06 |
| TW201144432A (en) | 2011-12-16 |
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