TWI577385B - 重組彈性蛋白酶蛋白質及其製備方法及用途 - Google Patents
重組彈性蛋白酶蛋白質及其製備方法及用途 Download PDFInfo
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- TWI577385B TWI577385B TW097147270A TW97147270A TWI577385B TW I577385 B TWI577385 B TW I577385B TW 097147270 A TW097147270 A TW 097147270A TW 97147270 A TW97147270 A TW 97147270A TW I577385 B TWI577385 B TW I577385B
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- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
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- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
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- C12Y—ENZYMES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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| TWI619726B (zh) * | 2007-12-04 | 2018-04-01 | 普堤昂治療有限公司 | 重組彈性蛋白酶蛋白質及其製備方法及用途 |
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| CN102250863B (zh) * | 2011-04-29 | 2012-12-05 | 天津金斯坦生物科技有限公司 | 基因重组人中性粒细胞弹性蛋白酶及其制备方法和该弹性蛋白酶的医药用途 |
| TWI636136B (zh) | 2013-03-15 | 2018-09-21 | 艾爾德生物製藥股份有限公司 | 在酵母菌及其它轉型細胞中多肽高產量表現用之溫度變動技術 |
| US10202630B2 (en) | 2013-03-15 | 2019-02-12 | Alderbio Holdings Llc | Temperature shift for high yield expression of polypeptides in yeast and other transformed cells |
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