TWI558419B - 用於降低或減少牙齒敏感性之口腔保健組成物 - Google Patents
用於降低或減少牙齒敏感性之口腔保健組成物 Download PDFInfo
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- TWI558419B TWI558419B TW099101691A TW99101691A TWI558419B TW I558419 B TWI558419 B TW I558419B TW 099101691 A TW099101691 A TW 099101691A TW 99101691 A TW99101691 A TW 99101691A TW I558419 B TWI558419 B TW I558419B
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- Prior art keywords
- composition
- cerium oxide
- acid
- oral
- tooth
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims description 201
- 230000035945 sensitivity Effects 0.000 title description 2
- 239000002245 particle Substances 0.000 claims description 185
- 229910000420 cerium oxide Inorganic materials 0.000 claims description 160
- BMMGVYCKOGBVEV-UHFFFAOYSA-N oxo(oxoceriooxy)cerium Chemical compound [Ce]=O.O=[Ce]=O BMMGVYCKOGBVEV-UHFFFAOYSA-N 0.000 claims description 159
- 239000000551 dentifrice Substances 0.000 claims description 85
- 238000000034 method Methods 0.000 claims description 63
- 210000004268 dentin Anatomy 0.000 claims description 62
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 56
- 229960003975 potassium Drugs 0.000 claims description 56
- 229910052700 potassium Inorganic materials 0.000 claims description 56
- 239000011591 potassium Substances 0.000 claims description 56
- -1 poly(1-phosphonopropyl) Polymers 0.000 claims description 45
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 42
- 229920000642 polymer Polymers 0.000 claims description 36
- 230000004907 flux Effects 0.000 claims description 35
- 239000003795 chemical substances by application Substances 0.000 claims description 34
- 210000005239 tubule Anatomy 0.000 claims description 34
- 239000012530 fluid Substances 0.000 claims description 33
- 239000000463 material Substances 0.000 claims description 31
- 239000000853 adhesive Substances 0.000 claims description 30
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- 230000036541 health Effects 0.000 claims description 28
- 239000002253 acid Substances 0.000 claims description 27
- 201000002170 dentin sensitivity Diseases 0.000 claims description 25
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- 229960003500 triclosan Drugs 0.000 claims description 24
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 23
- 239000011775 sodium fluoride Substances 0.000 claims description 21
- 235000013024 sodium fluoride Nutrition 0.000 claims description 21
- 239000000284 extract Substances 0.000 claims description 19
- 230000036347 tooth sensitivity Effects 0.000 claims description 19
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 claims description 15
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- 239000004475 Arginine Substances 0.000 claims description 13
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 13
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8164—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers, e.g. poly (methyl vinyl ether-co-maleic anhydride)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
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| US12/356,837 US20090186090A1 (en) | 2007-04-30 | 2009-01-21 | Oral Care Composition to Reduce or Eliminate Dental Sensitivity |
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| TW201036643A TW201036643A (en) | 2010-10-16 |
| TWI558419B true TWI558419B (zh) | 2016-11-21 |
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| AU (1) | AU2010210890B2 (enExample) |
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| MY (1) | MY159576A (enExample) |
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| TW (1) | TWI558419B (enExample) |
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| ZA (1) | ZA201104856B (enExample) |
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| TWI395595B (zh) * | 2009-04-01 | 2013-05-11 | Colgate Palmolive Co | 用於治療牙齒敏感之口腔用組成物及其使用方法與製造 |
| MX376901B (es) | 2010-03-31 | 2025-03-07 | Colgate Palmolive Co | Composicion para el cuidado oral. |
| CN102811698B (zh) | 2010-03-31 | 2016-01-13 | 高露洁-棕榄公司 | 口腔护理组合物 |
| WO2011162756A1 (en) | 2010-06-23 | 2011-12-29 | Colgate-Palmolive Company | Therapeutic oral composition |
| SG190023A1 (en) * | 2010-12-07 | 2013-06-28 | Colgate Palmolive Co | Dentifrice compositions containing calcium silicate |
| US9717929B2 (en) | 2010-12-07 | 2017-08-01 | Colgate-Palmolive Company | Dentifrice compositions containing calcium silicate and a basic amino acid |
| PH12013501078A1 (en) | 2010-12-20 | 2018-03-21 | Colgate Palmolive Co | Gelatin encapsulated oral care composition containing hydrophilic active hydrophobic structuring agent and oil carrier |
| CA2825139C (en) | 2011-01-31 | 2017-04-04 | Colgate-Palmolive Company | Oral care compositions |
| US8932060B2 (en) * | 2011-09-30 | 2015-01-13 | Kuraray Noritake Dental Inc. | Dental treatment method |
| US9333154B2 (en) * | 2012-01-12 | 2016-05-10 | M & O Solutions, Llc | Dual component oral composition for enhancing remineralization of teeth |
| CN104411287A (zh) | 2012-06-29 | 2015-03-11 | 高露洁-棕榄公司 | 包含微晶纤维素和羧甲基纤维素的高水含量口腔组合物 |
| US9134219B2 (en) * | 2012-08-31 | 2015-09-15 | Johnson & Johnson Consumer Inc. | Permeability flow cell and hydraulic conductance system |
| US9134217B2 (en) * | 2012-08-31 | 2015-09-15 | Johnson & Johnson Consumer Inc. | Permeability flow cell and hydraulic conductance system |
| JP6199871B2 (ja) | 2012-09-05 | 2017-09-20 | 株式会社サンギ | 口腔用組成物 |
| US20160067167A1 (en) * | 2012-11-15 | 2016-03-10 | Isp Investments Inc. | Oral care compositions for treatment of sensitive teeth |
| US20150374590A1 (en) * | 2013-03-19 | 2015-12-31 | University Of Washington Through Its Center For Commercialization | Artificial teeth |
| WO2015046491A1 (ja) * | 2013-09-30 | 2015-04-02 | クラレノリタケデンタル株式会社 | １材型の象牙細管封鎖材 |
| PT3137051T (pt) | 2014-04-28 | 2020-01-10 | Visionaturolab Inc | Composição de cuidados orais compreendendo pó de osso de choco e suas utilizações |
| US9927422B2 (en) * | 2014-05-13 | 2018-03-27 | The Procter & Gamble Company | Method and device for measuring dentin permeability |
| CN104188855B (zh) * | 2014-08-20 | 2017-04-12 | 广州立白企业集团有限公司 | 一种具有预防和缓解牙齿敏感作用的中药牙膏 |
| CN106999392A (zh) * | 2014-12-19 | 2017-08-01 | 高露洁-棕榄公司 | 牙齿美白口腔护理产品 |
| MX365971B (es) * | 2015-04-29 | 2019-06-21 | Colgate Palmolive Co | Composiciones para el cuidado bucal. |
| WO2017182240A1 (en) * | 2016-04-18 | 2017-10-26 | Unilever Plc | Oral care composition |
| USD823469S1 (en) | 2016-04-18 | 2018-07-17 | Conopco Inc. | Tooth cleaning appliance |
| KR102000521B1 (ko) * | 2017-03-02 | 2019-07-17 | 주식회사 지에이치바이오텍 | 구강 스프레이용 조성물 |
| CN107569395B (zh) * | 2017-09-04 | 2020-08-11 | 天津医科大学口腔医院 | 一种用于封闭牙本质小管使牙齿脱敏的材料 |
| US11033096B2 (en) | 2017-12-12 | 2021-06-15 | Colgate-Palmolive Company | Oral care refill head and oral care kit including the same |
| AU2017443357B2 (en) * | 2017-12-18 | 2022-01-27 | Gaba International Holding Gmbh | Oral care compositions |
| MX385755B (es) | 2018-03-29 | 2025-03-18 | Procter & Gamble | Composiciones para el cuidado bucal para promover la salud de las encias |
| JP7058341B2 (ja) | 2018-03-29 | 2022-04-21 | ザ プロクター アンド ギャンブル カンパニー | 歯肉健康を促進するための口腔ケア組成物 |
| CN111989083B (zh) | 2018-03-29 | 2024-02-13 | 宝洁公司 | 用于促进牙龈健康的口腔护理组合物 |
| MX383559B (es) | 2018-03-29 | 2025-03-14 | Procter & Gamble | Composiciones para el cuidado bucal para promover la salud de las encias |
| US12311044B2 (en) | 2018-12-18 | 2025-05-27 | Conopco, Inc. | Antimicrobial composition |
| US11304888B2 (en) | 2019-04-29 | 2022-04-19 | Sunstar Americas, Inc. | Oral care composition |
| WO2021062607A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Oral care compositions comprising hops beta acid and amino acid |
| JP7377963B2 (ja) | 2019-09-30 | 2023-11-10 | ザ プロクター アンド ギャンブル カンパニー | ホップベータ酸及び金属イオンを含む口腔ケア組成物 |
| WO2021062631A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Dentifrice compositions for treatment of dental biofilm |
| JP7414973B2 (ja) | 2019-09-30 | 2024-01-16 | ザ プロクター アンド ギャンブル カンパニー | 歯科バイオフィルムの処置のための歯磨剤組成物 |
| AU2020426517A1 (en) * | 2020-01-29 | 2022-08-18 | Rabbit Indústria E Comércio De Produtos De Higiene Pessoal Ltda | Oral composition with synergistic association of organic and inorganic components for complete maintenance of oral health, method for obtaining same and uses |
| CN113908067B (zh) * | 2021-10-19 | 2024-03-19 | 四川涑爽医疗用品有限公司 | 一种抗牙齿敏感的组合物及其制备方法与应用、包含该组合物的口腔护理产品 |
| CN119137460A (zh) * | 2022-04-05 | 2024-12-13 | 联合利华知识产权控股有限公司 | 口腔护理测量设备和方法 |
| CN118164493B (zh) * | 2024-02-29 | 2024-11-05 | 金三江(肇庆)硅材料股份有限公司 | 一种二氧化硅颗粒及其制备方法、口腔清洁护理组合物 |
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2009
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2010
- 2010-01-21 JP JP2011548085A patent/JP5865081B2/ja not_active Expired - Fee Related
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- 2010-01-21 MY MYPI2011002993A patent/MY159576A/en unknown
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2015
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080267891A1 (en) * | 2007-04-30 | 2008-10-30 | Colgate-Palmolive Company | Oral Care Composition To Reduce Or Eliminate Dental Sensitivity |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5865081B2 (ja) | 2016-02-17 |
| AU2010210890B2 (en) | 2012-11-29 |
| WO2010090855A2 (en) | 2010-08-12 |
| RU2011134912A (ru) | 2013-02-27 |
| US20090186090A1 (en) | 2009-07-23 |
| JP2012515780A (ja) | 2012-07-12 |
| CN102292125A (zh) | 2011-12-21 |
| SG172780A1 (en) | 2011-08-29 |
| TW201036643A (en) | 2010-10-16 |
| EP2389228A2 (en) | 2011-11-30 |
| CA2749189A1 (en) | 2010-08-12 |
| AU2010210890A1 (en) | 2011-07-14 |
| ZA201104856B (en) | 2014-12-23 |
| CA2749189C (en) | 2014-12-16 |
| AR075043A1 (es) | 2011-03-02 |
| JP2015232013A (ja) | 2015-12-24 |
| BRPI1007053B1 (pt) | 2017-06-27 |
| MX2011007235A (es) | 2011-08-03 |
| MY159576A (en) | 2017-01-13 |
| CO6382144A2 (es) | 2012-02-15 |
| BRPI1007053A2 (pt) | 2016-02-10 |
| WO2010090855A3 (en) | 2011-09-29 |
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