TWI543767B - Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 - Google Patents

Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 Download PDF

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Publication number
TWI543767B
TWI543767B TW098127226A TW98127226A TWI543767B TW I543767 B TWI543767 B TW I543767B TW 098127226 A TW098127226 A TW 098127226A TW 98127226 A TW98127226 A TW 98127226A TW I543767 B TWI543767 B TW I543767B
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Taiwan
Prior art keywords
peptide
antigen
hla
cancer
cytotoxic
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TW098127226A
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English (en)
Chinese (zh)
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TW201019952A (en
Inventor
角田卓也
大澤龍司
吉村祥子
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腫瘤療法 科學股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW098127226A 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 TWI543767B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8997208P 2008-08-19 2008-08-19

Publications (2)

Publication Number Publication Date
TW201019952A TW201019952A (en) 2010-06-01
TWI543767B true TWI543767B (zh) 2016-08-01

Family

ID=41707003

Family Applications (2)

Application Number Title Priority Date Filing Date
TW098127226A TWI543767B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗
TW103132024A TWI580431B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW103132024A TWI580431B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗

Country Status (16)

Country Link
US (1) US9119800B2 (cg-RX-API-DMAC7.html)
EP (1) EP2328600B9 (cg-RX-API-DMAC7.html)
JP (1) JP5633025B2 (cg-RX-API-DMAC7.html)
KR (1) KR101713581B1 (cg-RX-API-DMAC7.html)
CN (2) CN104958753B (cg-RX-API-DMAC7.html)
AU (1) AU2009283763B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0917391A2 (cg-RX-API-DMAC7.html)
CA (1) CA2734467C (cg-RX-API-DMAC7.html)
DK (1) DK2328600T3 (cg-RX-API-DMAC7.html)
ES (1) ES2566011T3 (cg-RX-API-DMAC7.html)
IL (1) IL211117A (cg-RX-API-DMAC7.html)
MX (2) MX337756B (cg-RX-API-DMAC7.html)
RU (1) RU2529373C2 (cg-RX-API-DMAC7.html)
SG (2) SG10201610206VA (cg-RX-API-DMAC7.html)
TW (2) TWI543767B (cg-RX-API-DMAC7.html)
WO (1) WO2010021112A1 (cg-RX-API-DMAC7.html)

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TWI494319B (zh) * 2007-02-21 2015-08-01 Oncotherapy Science Inc 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
EP2640842B1 (en) * 2010-11-17 2018-05-30 Aduro Biotech, Inc. Methods and compositions for inducing an immune response to egfrviii
WO2014010232A1 (en) 2012-07-10 2014-01-16 Oncotherapy Science, Inc. Ly6k epitope peptides for th1 cells and vaccines containing the same
CN106795204B (zh) * 2014-08-04 2021-09-28 肿瘤疗法科学股份有限公司 Urlc10衍生的肽和含有它们的疫苗
PL3335725T3 (pl) 2015-08-10 2024-07-22 Toray Industries, Inc. Epitopy PDS5A jako induktory odporności
CN112961213A (zh) 2015-08-12 2021-06-15 肿瘤疗法科学股份有限公司 Depdc1衍生的肽和包含它们的疫苗
JP7538601B2 (ja) 2017-04-26 2024-08-22 ユーリカ セラピューティックス, インコーポレイテッド キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用
DK3538645T3 (da) 2017-06-20 2021-04-19 Inst Curie Immunceller der mangler suv39h1
CN115300609A (zh) * 2021-05-08 2022-11-08 西湖大学 缺氧诱导脂滴相关蛋白(hilpda)在预防或治疗高血脂相关疾病中的应用

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US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
WO2001011044A1 (fr) * 1999-08-05 2001-02-15 Kyogo Itoh Antigene de tumeur
AU7748200A (en) 1999-09-30 2001-04-30 Varian Associates, Inc. Hypoxia-related human genes, proteins, and uses thereof
MXPA03003151A (es) 2000-10-13 2003-08-19 Eos Biotechnology Inc Metodos de diagnostico de cancer de prostata, composiciones y metodos para seleccionar moduladores de cancer de prostata.
US20030232350A1 (en) 2001-11-13 2003-12-18 Eos Biotechnology, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US20070015271A1 (en) 2002-04-04 2007-01-18 Rosen Craig A Human secreted proteins
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
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WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
CN1882698B (zh) * 2003-08-20 2011-05-25 肿瘤疗法科学股份有限公司 低氧可诱导的蛋白2(hig2)作为新的治疗肾细胞癌(rcc)的潜在标靶
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TWI494319B (zh) * 2007-02-21 2015-08-01 Oncotherapy Science Inc 表現腫瘤相關抗原之癌症的胜肽疫苗
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Also Published As

Publication number Publication date
IL211117A0 (en) 2011-04-28
AU2009283763A2 (en) 2011-07-07
MX355054B (es) 2018-04-03
EP2328600A4 (en) 2013-03-06
CN102186491B (zh) 2015-06-10
AU2009283763B2 (en) 2014-06-19
US9119800B2 (en) 2015-09-01
IL211117A (en) 2017-03-30
CA2734467A1 (en) 2010-02-25
SG10201610206VA (en) 2017-01-27
MX337756B (es) 2016-03-17
BRPI0917391A2 (pt) 2015-12-01
CN104958753A (zh) 2015-10-07
RU2011110376A (ru) 2012-09-27
DK2328600T3 (en) 2016-03-29
MX2011001883A (es) 2011-03-29
CA2734467C (en) 2017-10-03
WO2010021112A1 (en) 2010-02-25
EP2328600A1 (en) 2011-06-08
TWI580431B (zh) 2017-05-01
US20110243973A1 (en) 2011-10-06
EP2328600B9 (en) 2016-07-13
AU2009283763A1 (en) 2010-02-25
KR20110045052A (ko) 2011-05-03
EP2328600B1 (en) 2016-01-27
KR101713581B1 (ko) 2017-03-08
CN104958753B (zh) 2018-09-25
TW201500055A (zh) 2015-01-01
JP5633025B2 (ja) 2014-12-03
HK1157204A1 (zh) 2012-06-29
CN102186491A (zh) 2011-09-14
ES2566011T3 (es) 2016-04-08
RU2529373C2 (ru) 2014-09-27
JP2012500184A (ja) 2012-01-05
TW201019952A (en) 2010-06-01
SG193806A1 (en) 2013-10-30

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