TWI543767B - Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 - Google Patents

Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 Download PDF

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Publication number
TWI543767B
TWI543767B TW098127226A TW98127226A TWI543767B TW I543767 B TWI543767 B TW I543767B TW 098127226 A TW098127226 A TW 098127226A TW 98127226 A TW98127226 A TW 98127226A TW I543767 B TWI543767 B TW I543767B
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Taiwan
Prior art keywords
peptide
antigen
hla
cancer
cytotoxic
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TW098127226A
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English (en)
Chinese (zh)
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TW201019952A (en
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角田卓也
大澤龍司
吉村祥子
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腫瘤療法 科學股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW098127226A 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 TWI543767B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8997208P 2008-08-19 2008-08-19

Publications (2)

Publication Number Publication Date
TW201019952A TW201019952A (en) 2010-06-01
TWI543767B true TWI543767B (zh) 2016-08-01

Family

ID=41707003

Family Applications (2)

Application Number Title Priority Date Filing Date
TW098127226A TWI543767B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗
TW103132024A TWI580431B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW103132024A TWI580431B (zh) 2008-08-19 2009-08-13 Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗

Country Status (16)

Country Link
US (1) US9119800B2 (OSRAM)
EP (1) EP2328600B9 (OSRAM)
JP (1) JP5633025B2 (OSRAM)
KR (1) KR101713581B1 (OSRAM)
CN (2) CN104958753B (OSRAM)
AU (1) AU2009283763B2 (OSRAM)
BR (1) BRPI0917391A2 (OSRAM)
CA (1) CA2734467C (OSRAM)
DK (1) DK2328600T3 (OSRAM)
ES (1) ES2566011T3 (OSRAM)
IL (1) IL211117A (OSRAM)
MX (2) MX337756B (OSRAM)
RU (1) RU2529373C2 (OSRAM)
SG (2) SG10201610206VA (OSRAM)
TW (2) TWI543767B (OSRAM)
WO (1) WO2010021112A1 (OSRAM)

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Publication number Priority date Publication date Assignee Title
TWI610939B (zh) * 2007-02-21 2018-01-11 腫瘤療法 科學股份有限公司 表現腫瘤相關抗原之癌症的胜肽疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
SI2640842T1 (sl) * 2010-11-17 2018-09-28 Aduro Biotech, Inc. Postopki in sestavki za induciranje imunskega odziva na EGFRvIII
JP6255594B2 (ja) 2012-07-10 2018-01-10 オンコセラピー・サイエンス株式会社 Th1細胞のLY6Kエピトープペプチドおよびこれを含有するワクチン
US10576097B2 (en) * 2014-08-04 2020-03-03 Oncotherapy Science, Inc. URLC10-derived peptide and vaccine containing same
RU2758112C2 (ru) 2015-08-10 2021-10-26 Торэй Индастриз, Инк. Индуктор иммунитета
KR20180033585A (ko) 2015-08-12 2018-04-03 온코세라피 사이언스 가부시키가이샤 Depdc1-유래 펩티드 및 이를 포함하는 백신
IL310182A (en) 2017-04-26 2024-03-01 Eureka Therapeutics Inc ׂ A Delaware Corp Structures of chimeric antibody/T-cell receptor and uses thereof
PL3538645T3 (pl) 2017-06-20 2021-11-08 Institut Curie Komórki odpornościowe z defektem suv39h1
CN115300609A (zh) * 2021-05-08 2022-11-08 西湖大学 缺氧诱导脂滴相关蛋白(hilpda)在预防或治疗高血脂相关疾病中的应用

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US20070014787A1 (en) 1998-07-15 2007-01-18 Human Genome Sciences, Inc. 71 human secreted proteins
AU6318300A (en) * 1999-08-05 2001-03-05 Kyogo Itoh Tumor antigen
WO2001023426A2 (en) 1999-09-30 2001-04-05 Varian Associates, Inc. Hypoxia-related human genes, proteins, and uses thereof
JP2005506033A (ja) 2000-10-13 2005-03-03 イーオーエス バイオテクノロジー インコーポレイテッド 前立腺癌の診断法、前立腺癌モジュレータースクリーニングの組成物及び方法
US20030232350A1 (en) 2001-11-13 2003-12-18 Eos Biotechnology, Inc. Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
US20070015271A1 (en) 2002-04-04 2007-01-18 Rosen Craig A Human secreted proteins
TW200413725A (en) 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US20060024692A1 (en) 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
WO2005019258A2 (en) 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
WO2005019475A2 (en) * 2003-08-20 2005-03-03 Oncotherapy Science, Inc. Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc)
CA2570392A1 (en) * 2004-06-21 2005-12-29 Green Peptide Co., Ltd. Peptide vaccine for cancer therapy
CN101175862A (zh) 2005-02-10 2008-05-07 肿瘤疗法科学股份有限公司 诊断膀胱癌的方法
DK2325306T3 (en) 2005-02-25 2014-03-03 Oncotherapy Science Inc Peptide vaccines against lung cancers expressing TTK, URLC10 or KOC1 polypeptide
CA2599875A1 (en) 2005-03-03 2006-09-08 Takeda Pharmaceutical Company Limited Preventive/therapeutic agent for cancer
JP2009502112A (ja) 2005-07-28 2009-01-29 オンコセラピー・サイエンス株式会社 腎細胞癌を診断および処置するための方法
JP5116150B2 (ja) * 2005-09-07 2013-01-09 日本電気株式会社 Hla結合性ペプチド、それをコードするdna断片および組み換えベクター
JP4840858B2 (ja) * 2006-03-16 2011-12-21 学校法人慶應義塾 癌ワクチン
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TW201000115A (en) 2008-06-11 2010-01-01 Oncotherapy Science Inc IQGAP3 epitope peptides and vaccines containing the same
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same

Also Published As

Publication number Publication date
CN104958753B (zh) 2018-09-25
SG193806A1 (en) 2013-10-30
AU2009283763A2 (en) 2011-07-07
KR101713581B1 (ko) 2017-03-08
JP2012500184A (ja) 2012-01-05
MX355054B (es) 2018-04-03
EP2328600A1 (en) 2011-06-08
CA2734467A1 (en) 2010-02-25
US20110243973A1 (en) 2011-10-06
CN104958753A (zh) 2015-10-07
TW201019952A (en) 2010-06-01
US9119800B2 (en) 2015-09-01
EP2328600B1 (en) 2016-01-27
KR20110045052A (ko) 2011-05-03
CN102186491B (zh) 2015-06-10
MX2011001883A (es) 2011-03-29
WO2010021112A1 (en) 2010-02-25
CA2734467C (en) 2017-10-03
IL211117A0 (en) 2011-04-28
SG10201610206VA (en) 2017-01-27
AU2009283763A1 (en) 2010-02-25
IL211117A (en) 2017-03-30
HK1157204A1 (zh) 2012-06-29
BRPI0917391A2 (pt) 2015-12-01
JP5633025B2 (ja) 2014-12-03
CN102186491A (zh) 2011-09-14
DK2328600T3 (en) 2016-03-29
RU2529373C2 (ru) 2014-09-27
EP2328600B9 (en) 2016-07-13
RU2011110376A (ru) 2012-09-27
TWI580431B (zh) 2017-05-01
ES2566011T3 (es) 2016-04-08
TW201500055A (zh) 2015-01-01
AU2009283763B2 (en) 2014-06-19
EP2328600A4 (en) 2013-03-06
MX337756B (es) 2016-03-17

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