TWI516283B - 用於治療或預防肺病毒感染與相關疾病之組合物及方法 - Google Patents
用於治療或預防肺病毒感染與相關疾病之組合物及方法 Download PDFInfo
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Classifications
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- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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- A—HUMAN NECESSITIES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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Applications Claiming Priority (1)
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| EP (1) | EP2867216A4 (enExample) |
| JP (1) | JP2015524391A (enExample) |
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| WO (1) | WO2014005098A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2867216A4 (en) | 2012-06-29 | 2015-12-09 | Microdose Therapeutx Inc | COMPOSITIONS AND METHODS OF TREATING PNEUMOVIRAL INFECTIONS AND ASSOCIATED DISEASES |
| EP3233807B1 (de) * | 2014-12-18 | 2019-09-04 | MetrioPharm AG | Kristalline form von 5-amino-2,3-dihydrophthalazin-1,4-dion natriumsalz, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung |
| JP2018535277A (ja) * | 2015-11-30 | 2018-11-29 | ノヴァス・セラピューティクス・インコーポレーテッド | 耳科学的予防および処置のための組成物および方法 |
| WO2018071445A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| MX2021001820A (es) * | 2018-09-14 | 2021-04-28 | Pharmosa Biopharm Inc | Composicion farmaceutica para la liberacion controlada de farmacos acidos debiles y usos de los mismos. |
| CN109827875A (zh) * | 2019-04-10 | 2019-05-31 | 上海市食品药品检验所 | 一种用于测定吸入制剂溶出度的装置和方法 |
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| US6495580B1 (en) * | 1998-01-29 | 2002-12-17 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| WO1999038508A1 (en) | 1998-01-29 | 1999-08-05 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| WO2002059132A1 (en) | 2001-01-26 | 2002-08-01 | Viropharma Incorporated | Intermediate compounds useful for making antiviral compounds |
| EP1545513A2 (en) | 2002-08-09 | 2005-06-29 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| EP1539691A2 (en) | 2002-08-09 | 2005-06-15 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| EP2867216A4 (en) | 2012-06-29 | 2015-12-09 | Microdose Therapeutx Inc | COMPOSITIONS AND METHODS OF TREATING PNEUMOVIRAL INFECTIONS AND ASSOCIATED DISEASES |
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Also Published As
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| TW201416093A (zh) | 2014-05-01 |
| KR20150037946A (ko) | 2015-04-08 |
| WO2014005098A2 (en) | 2014-01-03 |
| WO2014005098A3 (en) | 2014-02-27 |
| MX2014015340A (es) | 2015-03-05 |
| ZA201409073B (en) | 2016-08-31 |
| EP2867216A4 (en) | 2015-12-09 |
| US9040569B2 (en) | 2015-05-26 |
| IL236476A0 (en) | 2015-02-26 |
| IN2014DN10680A (enExample) | 2015-08-28 |
| NZ628880A (en) | 2016-08-26 |
| US20140005239A1 (en) | 2014-01-02 |
| JP2015524391A (ja) | 2015-08-24 |
| US9504672B2 (en) | 2016-11-29 |
| HK1210163A1 (en) | 2016-04-15 |
| CN104507918A (zh) | 2015-04-08 |
| CA2877941A1 (en) | 2014-01-03 |
| HK1203956A1 (en) | 2015-11-06 |
| AU2013282286A1 (en) | 2015-01-22 |
| US20150209328A1 (en) | 2015-07-30 |
| EP2867216A2 (en) | 2015-05-06 |
| BR112014032290A2 (pt) | 2017-06-27 |
| EA201590124A1 (ru) | 2015-06-30 |
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