TWI453014B - 治療或預防疲勞之方法 - Google Patents

治療或預防疲勞之方法 Download PDF

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Publication number
TWI453014B
TWI453014B TW099120382A TW99120382A TWI453014B TW I453014 B TWI453014 B TW I453014B TW 099120382 A TW099120382 A TW 099120382A TW 99120382 A TW99120382 A TW 99120382A TW I453014 B TWI453014 B TW I453014B
Authority
TW
Taiwan
Prior art keywords
compound
fatigue
group
sleep
disease
Prior art date
Application number
TW099120382A
Other languages
English (en)
Chinese (zh)
Other versions
TW201105320A (en
Inventor
Moise A Khayrallah
Gary Bream
Stephen E Butts
Susan Marie Melnick
Duncan Taylor
Original Assignee
Sk Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Biopharmaceuticals Co Ltd filed Critical Sk Biopharmaceuticals Co Ltd
Publication of TW201105320A publication Critical patent/TW201105320A/zh
Application granted granted Critical
Publication of TWI453014B publication Critical patent/TWI453014B/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW099120382A 2009-06-22 2010-06-22 治療或預防疲勞之方法 TWI453014B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21908209P 2009-06-22 2009-06-22

Publications (2)

Publication Number Publication Date
TW201105320A TW201105320A (en) 2011-02-16
TWI453014B true TWI453014B (zh) 2014-09-21

Family

ID=43429751

Family Applications (1)

Application Number Title Priority Date Filing Date
TW099120382A TWI453014B (zh) 2009-06-22 2010-06-22 治療或預防疲勞之方法

Country Status (13)

Country Link
US (5) US8741950B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP2445490B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (3) JP6095366B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (3) KR102173587B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN106727486A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2010270971B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BRPI1015233A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2765463C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2012DN00624A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX2012000034A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2567801C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TWI453014B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2011005473A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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JP5024635B2 (ja) 2005-06-08 2012-09-12 エスケー バイオファーマスティカルズ カンパニー リミテッド 睡眠覚醒障害の治療
RU2567801C2 (ru) * 2009-06-22 2015-11-10 Ск Биофармасъютиклс Ко., Лтд. Способы лечения и профилактики усталости
WO2011055965A2 (en) 2009-11-06 2011-05-12 Sk Holdings Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
WO2011055944A2 (en) 2009-11-06 2011-05-12 Sk Holdings Co., Ltd. Methods for treating fibromyalgia syndrome
US8623913B2 (en) 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US9060994B2 (en) 2011-12-21 2015-06-23 Inno Biosciences, S.p.A. Combination therapy with interferon and andrographolides for Multiple Sclerosis
ES2927675T3 (es) * 2013-03-13 2022-11-10 Jazz Pharmaceuticals Ireland Ltd Tratamiento de la cataplexia
CN105848650A (zh) * 2013-07-12 2016-08-10 爵士制药国际Iii有限公司 促进吸烟停止
PL3021838T3 (pl) * 2013-07-18 2021-03-08 Jazz Pharmaceuticals Ireland Limited Leczenie otyłości
CN105682671A (zh) * 2013-11-08 2016-06-15 传统医疗保健有限公司 用于管理癌症和治疗癌症并存病的方法
US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
TWI655179B (zh) 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
JP7219213B2 (ja) 2016-09-06 2023-02-07 ジャズ ファーマスティカルズ アイルランド リミテッド (r)-2-アミノ-3-フェニルプロピルカルバメートの溶媒和物フォーム
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
WO2018067971A1 (en) 2016-10-06 2018-04-12 Jazz Pharmaceuticals International Iii Limited Carbamoyl phenylalaninol compounds and uses therof
WO2018124769A1 (ko) * 2016-12-30 2018-07-05 주식회사 동진쎄미켐 코팅 조성물 및 이로부터 제조되는 필름
NZ760594A (en) 2017-06-02 2025-05-02 Jazz Pharmaceuticals Ireland Ltd Methods and compositions for treating excessive sleepiness
US11413264B2 (en) 2017-07-31 2022-08-16 Jazz Pharmaceuticals Ireland Limited Carbamoyl phenylalaninol analogs and uses thereof
JP7428480B2 (ja) * 2019-06-06 2024-02-06 雪印メグミルク株式会社 睡眠改善用組成物及び組成物を含む食品、医薬品、飼料
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR102390194B1 (ko) * 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물
WO2023091921A1 (en) * 2021-11-16 2023-05-25 Axsome Malta Ltd. Methods and compositions for treating cognitive impairment
WO2025006965A1 (en) 2023-06-29 2025-01-02 Axsome Therapeutics, Inc. Methods of administering solriamfetol to lactating women

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WO2011055965A2 (en) 2009-11-06 2011-05-12 Sk Holdings Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
WO2011055944A2 (en) 2009-11-06 2011-05-12 Sk Holdings Co., Ltd. Methods for treating fibromyalgia syndrome
US8623913B2 (en) 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
ES2927675T3 (es) * 2013-03-13 2022-11-10 Jazz Pharmaceuticals Ireland Ltd Tratamiento de la cataplexia
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Also Published As

Publication number Publication date
US9464041B2 (en) 2016-10-11
CN106727486A (zh) 2017-05-31
US20200061017A1 (en) 2020-02-27
CA2765463C (en) 2018-10-09
KR20120098578A (ko) 2012-09-05
US20140243406A1 (en) 2014-08-28
AU2010270971B2 (en) 2015-08-20
JP6095366B2 (ja) 2017-03-15
KR102173587B1 (ko) 2020-11-04
JP2015214564A (ja) 2015-12-03
EP2445490A4 (en) 2019-10-23
KR20190105675A (ko) 2019-09-17
BRPI1015233A2 (pt) 2018-02-20
CA2765463A1 (en) 2011-01-13
RU2012101947A (ru) 2013-07-27
US9999609B2 (en) 2018-06-19
WO2011005473A2 (en) 2011-01-13
MX2012000034A (es) 2012-02-21
CN102481274A (zh) 2012-05-30
AU2010270971A1 (en) 2012-01-19
KR20170086710A (ko) 2017-07-26
JP2012530779A (ja) 2012-12-06
RU2567801C2 (ru) 2015-11-10
TW201105320A (en) 2011-02-16
WO2011005473A9 (en) 2011-05-12
US10507192B2 (en) 2019-12-17
US20180263950A1 (en) 2018-09-20
US8741950B2 (en) 2014-06-03
EP2445490A2 (en) 2012-05-02
JP2018188450A (ja) 2018-11-29
EP2445490B1 (en) 2023-02-08
IN2012DN00624A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-06-12
KR102021075B1 (ko) 2019-11-04
US20170000756A1 (en) 2017-01-05
JP6368285B2 (ja) 2018-08-01
US20120142769A1 (en) 2012-06-07

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