TWI406673B - 對抗4種登革熱血清型之免疫方法 - Google Patents

對抗4種登革熱血清型之免疫方法 Download PDF

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Publication number
TWI406673B
TWI406673B TW096135167A TW96135167A TWI406673B TW I406673 B TWI406673 B TW I406673B TW 096135167 A TW096135167 A TW 096135167A TW 96135167 A TW96135167 A TW 96135167A TW I406673 B TWI406673 B TW I406673B
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TW
Taiwan
Prior art keywords
vaccine
dengue virus
den
serotype
serotypes
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TW096135167A
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English (en)
Chinese (zh)
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TW200826959A (en
Inventor
Bruno Guy
Remi Forrat
Jean Lang
Veronique Barban
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Sanofi Pasteur
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Publication of TW200826959A publication Critical patent/TW200826959A/zh
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Publication of TWI406673B publication Critical patent/TWI406673B/zh

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW096135167A 2006-10-04 2007-09-20 對抗4種登革熱血清型之免疫方法 TWI406673B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0608660A FR2906724B1 (fr) 2006-10-04 2006-10-04 Methode d'immunisation contre les 4 serotypes de la dengue.

Publications (2)

Publication Number Publication Date
TW200826959A TW200826959A (en) 2008-07-01
TWI406673B true TWI406673B (zh) 2013-09-01

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
TW096135167A TWI406673B (zh) 2006-10-04 2007-09-20 對抗4種登革熱血清型之免疫方法
TW102119488A TW201336508A (zh) 2006-10-04 2007-09-20 對抗4種登革熱血清型之免疫方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW102119488A TW201336508A (zh) 2006-10-04 2007-09-20 對抗4種登革熱血清型之免疫方法

Country Status (15)

Country Link
US (2) US7718358B2 (cg-RX-API-DMAC7.html)
EP (3) EP2077857B1 (cg-RX-API-DMAC7.html)
JP (1) JP5269796B2 (cg-RX-API-DMAC7.html)
KR (1) KR20090064593A (cg-RX-API-DMAC7.html)
CN (2) CN101553251B (cg-RX-API-DMAC7.html)
AR (1) AR063057A1 (cg-RX-API-DMAC7.html)
AU (1) AU2007311792B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0719849A2 (cg-RX-API-DMAC7.html)
CA (1) CA2663885A1 (cg-RX-API-DMAC7.html)
FR (1) FR2906724B1 (cg-RX-API-DMAC7.html)
IL (2) IL197768A0 (cg-RX-API-DMAC7.html)
MX (1) MX2009003417A (cg-RX-API-DMAC7.html)
TW (2) TWI406673B (cg-RX-API-DMAC7.html)
WO (1) WO2008047023A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200901816B (cg-RX-API-DMAC7.html)

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FR2903605A1 (fr) * 2006-07-12 2008-01-18 Sanofi Pasteur Sa Methode d'immunisation contre les quatres serotypes de la dengue
FR2909286B1 (fr) * 2006-12-01 2012-06-08 Sanofi Pasteur Methode d'immunisation contre les 4 serotypes de la dengue
ES2615390T3 (es) 2008-03-05 2017-06-06 Sanofi Pasteur Proceso para estabilizar una composición de vacuna que contiene adyuvante
EP2143440A1 (fr) * 2008-07-09 2010-01-13 Sanofi Pasteur Agent stabilisant et composition vaccinale comprenant un ou plusieurs flavivirus vivants atténués
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PE20150356A1 (es) 2012-07-24 2015-03-20 Sanofi Pasteur Composiciones de vacuna para la prevencion contra la infeccion por el virus del dengue
US20150196631A1 (en) * 2012-07-24 2015-07-16 Sanofi Pasteur Vaccine compositions
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US9878031B2 (en) 2012-12-14 2018-01-30 Takeda Vaccines, Inc. Compositions, methods of administration and uses for trivalent dengue virus formulations
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AU2015369875A1 (en) 2014-12-22 2017-06-15 Merck Sharp & Dohme Corp. Dengue virus vaccine compositions and methods of use thereof
US10857222B2 (en) 2015-07-03 2020-12-08 Sanofi Pasteur Concomitant dengue and yellow fever vaccination
KR102297300B1 (ko) * 2015-11-27 2021-09-02 케이엠 바이올로직스 가부시키가이샤 뎅기 바이러스 약독주를 뱅크화한 생바이러스, 및 그것들을 항원으로 하는 뎅기 백신
EP3691681A1 (en) 2017-10-05 2020-08-12 Sanofi Pasteur Compositions for booster vaccination against dengu
PE20211545A1 (es) 2018-09-05 2021-08-16 Takeda Vaccines Inc Dosis unitaria de vacuna contra el dengue y administracion de esta
CN114555113A (zh) 2019-08-16 2022-05-27 武田疫苗股份有限公司 用于预防登革热和甲型肝炎的方法
US20240076631A2 (en) 2020-02-27 2024-03-07 Takeda Vaccines, Inc. Method for removing host cell dna from virus preparation
WO2023147337A2 (en) 2022-01-25 2023-08-03 Takeda Vaccines, Inc. Large-scale flaviviral vaccine production and manufacture
US20250177511A1 (en) 2022-02-15 2025-06-05 Takeda Vaccines, Inc. Dengue vaccine batch mixing process
WO2023215383A1 (en) 2022-05-04 2023-11-09 Takeda Vaccines, Inc. Computer-based determination of flavivirus infectivity
EP4375381A1 (en) 2022-11-18 2024-05-29 Takeda Vaccines, Inc. A method for determining the proportion of a live, attenuated flavivirus having a nucleotide sequence comprising at least one attenuation locus in a formulation
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WO2025072259A1 (en) 2023-09-25 2025-04-03 Takeda Vaccines, Inc. Coadministration of tetravalent dengue vaccine with hpv vaccine
WO2025122855A1 (en) 2023-12-08 2025-06-12 Takeda Vaccines, Inc. A method for determining the concentration of residual vero cell genomic dna in a sample containing virus obtained from production in vero cells

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Also Published As

Publication number Publication date
TW201336508A (zh) 2013-09-16
IL197768A0 (en) 2011-08-01
AR063057A1 (es) 2008-12-23
CN101553251A (zh) 2009-10-07
EP2077857B1 (fr) 2013-11-20
BRPI0719849A2 (pt) 2014-04-29
US7718358B2 (en) 2010-05-18
CN101553251B (zh) 2013-05-22
CA2663885A1 (en) 2008-04-24
MX2009003417A (es) 2009-04-09
CN103285386A (zh) 2013-09-11
EP2526965A1 (fr) 2012-11-28
EP2077857A2 (fr) 2009-07-15
KR20090064593A (ko) 2009-06-19
AU2007311792B2 (en) 2013-05-02
FR2906724A1 (fr) 2008-04-11
TW200826959A (en) 2008-07-01
WO2008047023A2 (fr) 2008-04-24
WO2008047023A3 (fr) 2008-10-23
FR2906724B1 (fr) 2009-03-20
JP2010505801A (ja) 2010-02-25
JP5269796B2 (ja) 2013-08-21
EP2526964A1 (fr) 2012-11-28
IL224572A (en) 2014-06-30
AU2007311792A1 (en) 2008-04-24
ZA200901816B (en) 2010-06-30
US20080085288A1 (en) 2008-04-10
US20100270202A1 (en) 2010-10-28

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