TWI388324B - 含有泊沙康唑（ｐｏｓａｃｏｎａｚｏｌｅ）之高密度組合物及包含該組合物之調配物 - Google Patents
含有泊沙康唑（ｐｏｓａｃｏｎａｚｏｌｅ）之高密度組合物及包含該組合物之調配物 Download PDFInfo
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- TWI388324B TWI388324B TW098112539A TW98112539A TWI388324B TW I388324 B TWI388324 B TW I388324B TW 098112539 A TW098112539 A TW 098112539A TW 98112539 A TW98112539 A TW 98112539A TW I388324 B TWI388324 B TW I388324B
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- posaconazole
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- hpmc
- polymer
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Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4517708P | 2008-04-15 | 2008-04-15 | |
| US16648709P | 2009-04-03 | 2009-04-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200946121A TW200946121A (en) | 2009-11-16 |
| TWI388324B true TWI388324B (zh) | 2013-03-11 |
Family
ID=41199703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| TW098112539A TWI388324B (zh) | 2008-04-15 | 2009-04-15 | 含有泊沙康唑（ｐｏｓａｃｏｎａｚｏｌｅ）之高密度組合物及包含該組合物之調配物 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20110123627A1 (enExample) |
| EP (1) | EP2285351A2 (enExample) |
| JP (3) | JP2011516612A (enExample) |
| KR (1) | KR20110004852A (enExample) |
| CN (2) | CN104983701A (enExample) |
| AR (1) | AR072858A1 (enExample) |
| AU (1) | AU2009236289B2 (enExample) |
| BR (1) | BRPI0910627A2 (enExample) |
| CA (1) | CA2720849A1 (enExample) |
| CL (1) | CL2009000902A1 (enExample) |
| CO (1) | CO6311066A2 (enExample) |
| MX (1) | MX2010011295A (enExample) |
| NZ (1) | NZ588460A (enExample) |
| PE (1) | PE20091778A1 (enExample) |
| PH (1) | PH12015500492A1 (enExample) |
| SG (1) | SG10201403986UA (enExample) |
| TW (1) | TWI388324B (enExample) |
| WO (1) | WO2009129300A2 (enExample) |
| ZA (1) | ZA201007370B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011516613A (ja) * | 2008-04-15 | 2011-05-26 | シェーリング コーポレイション | 好ましくはポサコナゾールおよびｈｐｍｃａｓを含む固体分散物中の経口用薬学的組成物 |
| JP5749247B2 (ja) | 2010-02-22 | 2015-07-15 | 第一三共株式会社 | 経口用徐放性固形製剤 |
| CN105283203B (zh) * | 2013-06-03 | 2018-12-28 | 信越化学工业株式会社 | 用于热熔挤出的组合物以及通过使用该组合物制备热熔挤出物的方法 |
| EP2837391B1 (en) * | 2013-08-12 | 2017-05-10 | Shin-Etsu Chemical Co., Ltd. | Hypromellose acetate succinate for use as hot-melt extrusion carrier, hot-melt extrusion composition, and method for producing hot-melt extrudate |
| CN104510707A (zh) * | 2013-09-26 | 2015-04-15 | 博瑞生物医药技术(苏州)有限公司 | 一种泊沙康唑固体分散体及其制备方法 |
| CN104546667A (zh) * | 2013-10-22 | 2015-04-29 | 博瑞生物医药技术(苏州)有限公司 | 含泊沙康唑的固体分散体及其制备方法 |
| CN104721827A (zh) * | 2013-12-18 | 2015-06-24 | 博瑞生物医药技术(苏州)有限公司 | 一种难溶性抗真菌药物固体分散体及其制备方法 |
| RU2019123406A (ru) | 2014-02-05 | 2019-10-03 | Мерк Шарп И Доум Корп. | Технология приготовления таблеток для cgrp-активных соединений |
| CN104971045A (zh) * | 2014-04-11 | 2015-10-14 | 上海宣泰医药科技有限公司 | 泊沙康唑药物组合物及其制备方法和药物制剂 |
| WO2017025292A1 (en) | 2015-08-08 | 2017-02-16 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant formulation containing posaconazole |
| EP4424308A3 (en) | 2016-02-26 | 2024-12-04 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| CN106265526A (zh) * | 2016-09-22 | 2017-01-04 | 山东大学 | 一种抗真菌药物泊沙康唑的固体分散体及制备方法与应用 |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| US20180282527A1 (en) * | 2017-03-30 | 2018-10-04 | Shin-Etsu Chemical Co., Ltd. | Injection molding composition containing hypromellose acetate succinate and method for producing same |
| US10702520B1 (en) | 2019-01-29 | 2020-07-07 | Slayback Pharma Llc | Pharmaceutical compositions of posaconazole |
| US20230149452A1 (en) * | 2020-04-06 | 2023-05-18 | Yogesh BENDALE | Structurally defined, better tolerated, orally adminstered, processed arsenolite, a process for its preparation, a pharmaceutical composition and uses thereof |
| US20240293399A1 (en) | 2020-08-13 | 2024-09-05 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant high-strength formulation containing posaconazole |
| CN112697937A (zh) * | 2020-12-18 | 2021-04-23 | 卓和药业集团有限公司 | 泊沙康唑肠溶片溶出度的分析方法 |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
| WO2023012378A1 (en) | 2021-11-25 | 2023-02-09 | Alfred E. Tiefenbacher (Gmbh Und Co. Kg) | Granules containing posaconazole |
| CN114184721A (zh) * | 2021-12-14 | 2022-03-15 | 江苏恒盛药业有限公司 | 泊沙康唑残留溶剂的检测方法 |
| CN115721601A (zh) * | 2022-11-23 | 2023-03-03 | 无锡福祈制药有限公司 | 一种泊沙康唑纳米晶口服固体药物组合物及其制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4144346A (en) * | 1977-01-31 | 1979-03-13 | Janssen Pharmaceutica N.V. | Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
| US4916134A (en) * | 1987-03-25 | 1990-04-10 | Janssen Pharmacuetica N.V. | 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]me]phenyl]-1-piperazinyl]phenyl]triazolones |
| GB8908250D0 (en) * | 1989-04-12 | 1989-05-24 | Fisons Plc | Formulations |
| US5278175A (en) * | 1990-02-02 | 1994-01-11 | Pfizer Inc. | Triazole antifungal agents |
| US5661151A (en) * | 1993-12-21 | 1997-08-26 | Schering Corporation | Tetrahydrofuran antifungals |
| US5703079A (en) * | 1993-12-21 | 1997-12-30 | Schering Corporation | Tetrahydrofuran antifungals |
| NZ270418A (en) * | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
| GB9602080D0 (en) * | 1996-02-02 | 1996-04-03 | Pfizer Ltd | Pharmaceutical compounds |
| CN1165291C (zh) * | 1996-05-20 | 2004-09-08 | 詹森药业有限公司 | 具有改进的生物利用度的抗真菌组合物 |
| US5834472A (en) * | 1996-05-24 | 1998-11-10 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| US5972381A (en) * | 1996-06-28 | 1999-10-26 | Schering Corporation | Solid solution of an antifungal agent with enhanced bioavailability |
| US5846971A (en) * | 1996-06-28 | 1998-12-08 | Schering Corporation | Oral antifungal composition |
| US6713481B1 (en) * | 1997-10-17 | 2004-03-30 | David R. Andrews | Crystalline antifungal polymorph |
| CA2396380C (en) * | 1999-12-23 | 2015-04-21 | David Hayes | Improved pharmaceutical compositions for poorly soluble drugs |
| UY26615A1 (es) * | 2000-03-16 | 2001-10-25 | Pfizer Prod Inc | Inhibidor de la glucogeno fosforilasa. |
| EP1372394A1 (en) * | 2001-04-03 | 2004-01-02 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| WO2003077827A1 (en) * | 2002-03-19 | 2003-09-25 | Nippon Shinyaku Co., Ltd. | Process for producing drug solid dispersion |
| US20050043251A1 (en) * | 2003-08-20 | 2005-02-24 | Fairfield Clinical Trials, Llc | Method of treatment of otitis externa |
| US20060160823A1 (en) * | 2004-05-28 | 2006-07-20 | Leonore Witchey-Lakshmanan | Particulate-stabilized injectable pharmaceutical compositions of Posaconazole |
| US20060062848A1 (en) * | 2004-09-17 | 2006-03-23 | Nektar Therapeutics Uk Limited | Formulation comprising itraconazole |
| US20060275230A1 (en) * | 2004-12-10 | 2006-12-07 | Frank Kochinke | Compositions and methods for treating conditions of the nail unit |
| JP2009514884A (ja) * | 2005-11-04 | 2009-04-09 | イーストマン ケミカル カンパニー | 難溶性医薬活性剤の投与のためのカルボキシアルキルセルロースエステル |
| CN101495096A (zh) * | 2006-05-30 | 2009-07-29 | 伊兰制药国际有限公司 | 纳米微粒泊沙康唑制剂 |
| WO2008138755A2 (en) * | 2007-05-11 | 2008-11-20 | F. Hoffmann-La Roche Ag | Pharmaceutical compositions for poorly soluble drugs |
| JP2011516613A (ja) * | 2008-04-15 | 2011-05-26 | シェーリング コーポレイション | 好ましくはポサコナゾールおよびｈｐｍｃａｓを含む固体分散物中の経口用薬学的組成物 |
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2009
- 2009-04-15 SG SG10201403986UA patent/SG10201403986UA/en unknown
- 2009-04-15 TW TW098112539A patent/TWI388324B/zh active
- 2009-04-15 PE PE2009000520A patent/PE20091778A1/es active IP Right Grant
- 2009-04-15 CN CN201510421108.2A patent/CN104983701A/zh active Pending
- 2009-04-15 BR BRPI0910627A patent/BRPI0910627A2/pt not_active IP Right Cessation
- 2009-04-15 AR ARP090101320A patent/AR072858A1/es unknown
- 2009-04-15 EP EP09732010A patent/EP2285351A2/en not_active Withdrawn
- 2009-04-15 MX MX2010011295A patent/MX2010011295A/es active IP Right Grant
- 2009-04-15 KR KR1020107023010A patent/KR20110004852A/ko not_active Ceased
- 2009-04-15 NZ NZ588460A patent/NZ588460A/en unknown
- 2009-04-15 WO PCT/US2009/040652 patent/WO2009129300A2/en not_active Ceased
- 2009-04-15 CL CL2009000902A patent/CL2009000902A1/es unknown
- 2009-04-15 JP JP2011505163A patent/JP2011516612A/ja not_active Ceased
- 2009-04-15 AU AU2009236289A patent/AU2009236289B2/en not_active Expired - Fee Related
- 2009-04-15 CN CN2009801224878A patent/CN102065842A/zh active Pending
- 2009-04-15 US US12/999,547 patent/US20110123627A1/en not_active Abandoned
- 2009-04-15 CA CA2720849A patent/CA2720849A1/en not_active Abandoned
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2010
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- 2010-11-11 CO CO10141841A patent/CO6311066A2/es not_active Application Discontinuation
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2014
- 2014-04-02 JP JP2014075980A patent/JP2014139230A/ja active Pending
- 2014-11-24 US US14/551,903 patent/US20150150990A1/en not_active Abandoned
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2015
- 2015-03-06 PH PH12015500492A patent/PH12015500492A1/en unknown
- 2015-11-24 JP JP2015228422A patent/JP2016074698A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010011295A (es) | 2010-11-12 |
| AU2009236289A1 (en) | 2009-10-22 |
| US20110123627A1 (en) | 2011-05-26 |
| PH12015500492A1 (en) | 2017-04-10 |
| KR20110004852A (ko) | 2011-01-14 |
| EP2285351A2 (en) | 2011-02-23 |
| WO2009129300A3 (en) | 2010-02-11 |
| JP2016074698A (ja) | 2016-05-12 |
| PE20091778A1 (es) | 2009-11-13 |
| CN104983701A (zh) | 2015-10-21 |
| NZ588460A (en) | 2012-07-27 |
| AU2009236289B2 (en) | 2014-08-21 |
| CL2009000902A1 (es) | 2010-07-23 |
| TW200946121A (en) | 2009-11-16 |
| CN102065842A (zh) | 2011-05-18 |
| AR072858A1 (es) | 2010-09-29 |
| JP2014139230A (ja) | 2014-07-31 |
| JP2011516612A (ja) | 2011-05-26 |
| BRPI0910627A2 (pt) | 2015-09-22 |
| CA2720849A1 (en) | 2009-10-22 |
| ZA201007370B (en) | 2011-06-29 |
| SG10201403986UA (en) | 2014-10-30 |
| US20150150990A1 (en) | 2015-06-04 |
| WO2009129300A2 (en) | 2009-10-22 |
| CO6311066A2 (es) | 2011-08-22 |
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