TWI360422B - - Google Patents
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- Publication number
- TWI360422B TWI360422B TW95126182A TW95126182A TWI360422B TW I360422 B TWI360422 B TW I360422B TW 95126182 A TW95126182 A TW 95126182A TW 95126182 A TW95126182 A TW 95126182A TW I360422 B TWI360422 B TW I360422B
- Authority
- TW
- Taiwan
- Prior art keywords
- lactic acid
- health care
- fermentation broth
- care composition
- hours
- Prior art date
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N Lactic Acid Natural products CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 69
- 241000894006 Bacteria Species 0.000 claims description 51
- 238000000855 fermentation Methods 0.000 claims description 45
- 230000004151 fermentation Effects 0.000 claims description 45
- 235000014655 lactic acid Nutrition 0.000 claims description 35
- 239000004310 lactic acid Substances 0.000 claims description 35
- 239000000203 mixture Substances 0.000 claims description 20
- 241000186660 Lactobacillus Species 0.000 claims description 18
- 229940039696 lactobacillus Drugs 0.000 claims description 16
- 210000001215 vagina Anatomy 0.000 claims description 14
- 210000004392 genitalia Anatomy 0.000 claims description 9
- 235000013336 milk Nutrition 0.000 claims description 9
- 239000008267 milk Substances 0.000 claims description 9
- 210000004080 milk Anatomy 0.000 claims description 9
- 230000036541 health Effects 0.000 claims description 8
- 244000052769 pathogen Species 0.000 claims description 8
- 241000588724 Escherichia coli Species 0.000 claims description 7
- 208000005448 Trichomonas Infections Diseases 0.000 claims description 6
- 230000001717 pathogenic effect Effects 0.000 claims description 6
- 239000006041 probiotic Substances 0.000 claims description 6
- 235000018291 probiotics Nutrition 0.000 claims description 6
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims description 5
- 241000191967 Staphylococcus aureus Species 0.000 claims description 5
- 241000194017 Streptococcus Species 0.000 claims description 5
- 206010048461 Genital infection Diseases 0.000 claims description 4
- 206010044620 Trichomoniasis Diseases 0.000 claims description 4
- 239000006071 cream Substances 0.000 claims description 3
- 201000010099 disease Diseases 0.000 claims description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 3
- 239000000499 gel Substances 0.000 claims description 3
- 238000011282 treatment Methods 0.000 claims description 3
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- 208000015181 infectious disease Diseases 0.000 description 9
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 230000028327 secretion Effects 0.000 description 8
- 241000700198 Cavia Species 0.000 description 7
- 241000283973 Oryctolagus cuniculus Species 0.000 description 7
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- 208000035143 Bacterial infection Diseases 0.000 description 6
- 206010046914 Vaginal infection Diseases 0.000 description 6
- 208000022362 bacterial infectious disease Diseases 0.000 description 6
- 238000010181 skin prick test Methods 0.000 description 6
- VYZAHLCBVHPDDF-UHFFFAOYSA-N Dinitrochlorobenzene Chemical compound [O-][N+](=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 VYZAHLCBVHPDDF-UHFFFAOYSA-N 0.000 description 5
- 241000700159 Rattus Species 0.000 description 5
- 230000000172 allergic effect Effects 0.000 description 5
- 208000010668 atopic eczema Diseases 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 210000004209 hair Anatomy 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 241001465754 Metazoa Species 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 4
- 206010036790 Productive cough Diseases 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 230000006698 induction Effects 0.000 description 4
- 238000001223 reverse osmosis Methods 0.000 description 4
- 208000024794 sputum Diseases 0.000 description 4
- 210000003802 sputum Anatomy 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 241000239226 Scorpiones Species 0.000 description 3
- 241000191940 Staphylococcus Species 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
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- 230000005906 menstruation Effects 0.000 description 3
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- 150000003431 steroids Chemical class 0.000 description 3
- 230000002485 urinary effect Effects 0.000 description 3
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 241000222120 Candida <Saccharomycetales> Species 0.000 description 2
- 241000222122 Candida albicans Species 0.000 description 2
- 241000700199 Cavia porcellus Species 0.000 description 2
- 241000588722 Escherichia Species 0.000 description 2
- 206010017533 Fungal infection Diseases 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 239000006391 Luria-Bertani Medium Substances 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- 241000555745 Sciuridae Species 0.000 description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 2
- 201000008100 Vaginitis Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 206010013023 diphtheria Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000009329 sexual behaviour Effects 0.000 description 2
- 229910052938 sodium sulfate Inorganic materials 0.000 description 2
- 235000011152 sodium sulphate Nutrition 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 208000002003 vulvitis Diseases 0.000 description 2
- XCFIBNWBWLZWDB-UHFFFAOYSA-N 5-chloro-1,5-dinitrocyclohexa-1,3-diene Chemical compound [O-][N+](=O)C1=CC=CC(Cl)([N+]([O-])=O)C1 XCFIBNWBWLZWDB-UHFFFAOYSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 229930182843 D-Lactic acid Natural products 0.000 description 1
- JVTAAEKCZFNVCJ-UWTATZPHSA-N D-lactic acid Chemical compound C[C@@H](O)C(O)=O JVTAAEKCZFNVCJ-UWTATZPHSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 240000001929 Lactobacillus brevis Species 0.000 description 1
- 235000013957 Lactobacillus brevis Nutrition 0.000 description 1
- 244000199885 Lactobacillus bulgaricus Species 0.000 description 1
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 description 1
- 241000186840 Lactobacillus fermentum Species 0.000 description 1
- 241000218588 Lactobacillus rhamnosus Species 0.000 description 1
- 241000257159 Musca domestica Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 244000292604 Salvia columbariae Species 0.000 description 1
- 235000012377 Salvia columbariae var. columbariae Nutrition 0.000 description 1
- 235000001498 Salvia hispanica Nutrition 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 206010040914 Skin reaction Diseases 0.000 description 1
- 206010070835 Skin sensitisation Diseases 0.000 description 1
- 206010046461 Urethral pain Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 235000020299 breve Nutrition 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 235000014167 chia Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000002327 eosinophilic effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 229940068140 lactobacillus bifidus Drugs 0.000 description 1
- 229940004208 lactobacillus bulgaricus Drugs 0.000 description 1
- 229940012969 lactobacillus fermentum Drugs 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000035483 skin reaction Effects 0.000 description 1
- 231100000430 skin reaction Toxicity 0.000 description 1
- 231100000370 skin sensitisation Toxicity 0.000 description 1
- 239000006104 solid solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW95126182A TW200806303A (en) | 2006-07-18 | 2006-07-18 | Composition applied to female pudendum |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW95126182A TW200806303A (en) | 2006-07-18 | 2006-07-18 | Composition applied to female pudendum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200806303A TW200806303A (en) | 2008-02-01 |
| TWI360422B true TWI360422B (https=) | 2012-03-21 |
Family
ID=44766295
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW95126182A TW200806303A (en) | 2006-07-18 | 2006-07-18 | Composition applied to female pudendum |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TW200806303A (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI754126B (zh) * | 2018-07-19 | 2022-02-01 | 大江生醫股份有限公司 | 益生質組合物用於改善女性陰道內的菌相的用途及外用衛生用品 |
-
2006
- 2006-07-18 TW TW95126182A patent/TW200806303A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200806303A (en) | 2008-02-01 |
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