TWI332830B - Accommodative intraocular lens system - Google Patents

Accommodative intraocular lens system Download PDF

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Publication number
TWI332830B
TWI332830B TW096115016A TW96115016A TWI332830B TW I332830 B TWI332830 B TW I332830B TW 096115016 A TW096115016 A TW 096115016A TW 96115016 A TW96115016 A TW 96115016A TW I332830 B TWI332830 B TW I332830B
Authority
TW
Taiwan
Prior art keywords
crystal
ring
modulating
crystal system
artificial
Prior art date
Application number
TW096115016A
Other languages
English (en)
Other versions
TW200803805A (en
Inventor
Trung Tran Son
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of TW200803805A publication Critical patent/TW200803805A/zh
Application granted granted Critical
Publication of TWI332830B publication Critical patent/TWI332830B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648—Multipart lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0053—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in optical properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Eyeglasses (AREA)

Description

1332830 九、發明說明：
t 明所屬之技領；J 本發明係為一種調節式人工水晶體系統。
L先前技術：J 5 發明背景 本發明通常與人工水晶體(IOL)的領域有關，且更特別 地係與調節式IOLs有關。 人類眼睛之最簡要功能係藉著將光通過一被稱為角膜 的透明外側部分，並將影像以水晶體聚焦在視網膜上來提 10供視覺。遠經I焦的影像之品質會依據包括了眼睛的尺寸 和形狀，以及角膜和水晶體的透明度等等之許多因素而有 不同。 S年齡或疾病導致水晶體變得比較不透明時，視覺將 會因為被傳送到視網膜的光減少而惡化。在眼睛水晶體中 15的該缺陷係在醫學上被稱為白内障。此一病況可以接受的 治療係為以外科手術切除水晶體，並以人工水晶體(I0L)來 取代水晶體的功能的替換的移動。 在美國大多數的内障性水晶體係以一種被稱為水晶體 乳化術(phacoemulsification)的外科手術來移除。在這個手 20術期間，會在水晶體前囊部造成一開口並將一細水晶體乳 化尖端插入該產生病變的水晶體内而以超音波加以振動。 該振動切割尖端會將該水晶體液化或乳化，以使得該水晶 體可以被吸出眼睛。一旦該產生病變的水晶體被移除，其 將被以一人工水晶體來替換。 5 在天然水晶體中’遠距離與近距離的視覺效果之雙焦 距特性’係由被稱為調適作用（accommodation)的機制所提 供。在生涯早期，天然水晶體係為柔軟的並且被容納在囊 袋裡面。該囊袋子係被睫狀小帶而以睫狀肌懸吊。鬆弛睫 狀肌會使得睫狀小帶拉緊並延伸展該囊袋。結果，天然水 晶體會變得扁平。拉緊睫狀肌會使得睫狀小帶的張力鬆 弛’而允許囊袋與天然水晶體形成更接近圓形的形狀。藉 著這種方法，天然水晶體可以聚焦在較近與較遠的物體上。 隨著水晶體老化，其會變得比較難於並且比較無法因 應睫狀肌拉緊反應而改變形狀。這使得水晶體更難以對較 近物體聚焦，也就是被稱為老花眼的醫學病況。老花眼會 影響幾乎所有的在45或50歲以上之成年人。 在本發明之前，當一白内障或其他疾病需要將天然水 晶體移除並以一係為單焦距水晶體之人工的I〇L進行替換 時’該患者需要使用一對用於近距離視覺的眼鏡或隱形眼 鏡。先進醫學光學公司（Advanced Medical Optics)已經有販 賣雙焦點IOL(陣列式水晶體）許多年，但是由於品質的問 題’這種水晶體尚未被廣泛地被接受。 對於調節式的IOLs的一些設計的研究正在進行。舉例 來說’ C& C Vision願景公司所製造的一些設計現在正在進 行臨床實驗。參照美國專利第6，197,059、5,674,282、 5,496,366和5,476,514(頒發給Cumming)，其等之整體内容均 在此被併入以供參考❶在這些專利中所描述的水晶體係為 具有可撓性支撐腳(haptic) ’以允許該光學元件因應該睫狀 肌的運動而向前地和向後地移動。類似的設計係被描述在 美國專利第 6,302,911 B1號(頒發給Hanna)、第 6,261，321，B1 號，以及6241777 B1號（這兩件都頒發給Kellan)中，其等之 整體内容均在此被併入以供參考。然而，在這些單一水晶 體系統中之該光學元件的位移量，可能不足以形成有用的 調節範圍。此外，被如美國專利第6,197,059、5,674,282、 5,496,366與5,476,514號中所描述的，該眼睛必需被麻醉1_2 個星期以使得囊袋纖維化而固定該水晶體，並藉此在該囊 袋與水晶體之間提供一牢固的連結作用。除此之外，這些 水晶體的商業化型式是利用水凝膠或矽基材料製成。此等 材料本身並無法避免後發性白内障（"PCO")的產生❶PCO的 唯一治療方式是使用Nd:YAG雷射來將該後段囊袋的一部 分蒸發。此等對後段囊袋部分的損傷，可能會破壞這些水 晶體的調節機制。 目前已經進行一些要製造一雙光學元件可調式水晶體 系統。舉例來說，美國專利第5,275,623號(Sarfarazi)、WIPO 公告第 00/66037 號（Glick 等人）以及 WO 01/34067 A1 (Bandhauer等人），均揭示一種雙光學元件水晶體系統，其 之一光學元件具有正放大率而另一光學元件具有負放大 率，該等文獻之整體内容均在此被併入以供參考。該等光 學元件係由一會對睫狀肌的運動產生反應之鉸鏈機構所連 接，以將該等光學元件移動得比較靠近或更加遠離，藉此 提供調節作用。為了要提供這種"鏡頭伸縮”效果，睫狀肌 的運動一定要被適當地經過囊袋而傳輸至該水晶體系統， 並且這些 :設計都無 參考文獻都沒有揭示用於確保在該囊袋與該系統 之間的緊达、連結之機制。除此之外，這些水晶體 、、 法克服上述的PCO之問題。 因此，目前仍需要一種可以提供範圍寬廣而有效之安 全且穩定的可調式眼内的水晶體系統。 【智h明内容】 發明概要 本發明藉由提供-種雙光學元件可調式水晶體系統來 改良習知技藝術。該第一水晶體具有負放大率並且係位在 4囊袋内的後方，並係相對於該後囊而置放。該第—水晶 體的周圍係被附接至—具有著側壁的環狀結構。該第二: 晶體係位在該第-水晶體的前側之囊袋裡面並且係具有正 放大率。該第二個水晶體的邊緣包含有數個支擇腳， 其等係被架構成螺旋狀獻係自該第二水晶體向後地並朝 向該第-水晶體突出。鱗支撑腳係相對牢固又仍然具有 彈性的’並且係架騎(ride)於該環狀結構的側壁裡面，因此 該囊袋會因應於該睫狀賴運動㈣平或突起，而導致該 第二水晶體沿著該水晶體系統的光轴移動。 因此，本發明之一目的係要提供一種安全和生物上可 適用的人工水晶體。 本發明的另一個目的係要提供一種安全且生物上可適 用的人工水晶體，其係易於被植入該後端腔室内。 本發明的又另一個目的係要提供一種安全且生物上可 適用的人工水晶體，其在該後端腔室内係為安定的。 本發明的又另一個目的係要提供一種安全且生物上可 適用的可調式水晶體。 ^本發明的這些和其他優點與目的，將可由下述之詳細 知述與申請專利範圍而變得明顯。 5圖式簡單說明 第1圖是本發明的水晶體系統之放大的分解透視圖。 第2圖疋本發明的水晶體系統之該第一水晶體的放大 透视圖。 第3圖是本發明的水晶體系統的該第一水晶體的被放 10 大剖面圖。 第4圖疋本發明的水晶體系統之第二水晶體的放大頂 面圖。 第5圖是本發明的水晶體系統之第二水晶體的放大正 視圖。 15 【貧施方式】 較佳實施例之詳細說明 如可以在該等圖示中所充份了解的，本發明的水晶體 糸統10通常係由後側水晶體12、前側水晶體14以及周邊環 16所組成。水晶體12係較佳地與環16為一體成形。水晶體 20 12較佳地由例如軟壓克力之一本質上可以避免PCO的形成 之柔軟又可摺疊的材料所製成。水晶體14係較佳地由例如 水凝膠、矽膠或軟壓克力等等柔軟而可摺疊的材料所製 成。水晶體12可以具有任何的適當放大率，但是其係較佳 地具有負放大率。水晶體14也可以是任何的適當放大率， 9 但是其較佳地具有正放大率。水晶體12和14的相對放大率 應該要使得水晶體14朝向或遠離水晶體12之軸向運動，能 夠足以將水晶體系統1〇的整體放大率調整至至少一個屈光 率，且較佳地至少有3-4個屈光率，習於眼睛水晶體之設計 的技藝者，應該能夠利用例如下列等式來計算水晶體12和 14之放大率： P = PI + Ρ2 - Τ/η * Ρ1Ρ2 ⑴ δΡ = -δΤ/η * Ρ1Ρ2 ⑺ 水晶體12係大略相對於光軸22而對稱的。以環16與水 晶體12連接之周邊環帶18係相對地較為堅硬，因而允許因 應睫狀肌收縮與放鬆的一些未過量之撓曲。周邊環帶18可 以包含數個孔洞19，以允許在手術期間由光學元件12及/或 環帶18後方進行之任何黏彈性材料的釋放或抽取作用。環 16通常具有向前突出之垂直側壁28。水晶體14包含數個自 水晶體14的光學元件24向外突出，並沿著光軸22遠離水晶 體14的光學元件24之支撐腳20〇第二可撓性支撐腳2〇係藉 著相對較為堅固之區域26而連接到水晶體14，以允許第二 可撓性支#腳20具有拮抗彈性運動。在其被壓縮時，第二 支樓腳20會蓄積動能，而在未被麼縮時釋放出該能量。區 域26也會協助在該前端囊袋（未顯示）與該光學元件％之間 形成一間隔，以允許液體在該光學元件24之前端與後端之 間流動。 在使用中，水晶體12係在進行該水晶體的植入作用 之前被植入該囊袋内。水晶體12係藉由環16而維持在該囊 袋裡面。水晶體14係植入以使得第二支撐腳20係架在該環 16的側壁28裡面。水晶體12和14彼此自由浮動而不會接 觸。在植入水晶體14時，支撐腳20會因應該水晶體囊袋因 為睫狀肌的收縮和放鬆而導致的變平與突起現像而撓曲。 由睫狀肌放鬆所導致的囊袋變平之現象將會軸向地壓縮支 撐腳20並允許第二光學元件24沿著水晶體12的光軸22向後 地移動。由睫狀肌的收縮所導致的懸韌帶張力鬆弛將會允 許蓄積在經過壓縮的支撐腳20中之動能被釋放，使得水晶 體12的光學元件24會因為該支撐腳的2〇之拱頂與螺旋形結 構’而沿著光軸22向前地移動並遠離水晶體12。 本發明說明僅用於例示說明與解說之目的。習於相關 技藝者將會瞭解，上述發明可以在不背離其之範圍或精神 下進行改變與修正。 【圖式簡單說明】 第1圖疋本發明的水晶體系統之放大的分解透視圖。 第2圖是本發明的水晶體系統之該第一水晶體的放大 透視圖。 第3圖是本發明的水晶體系統的該第一水晶體的被放 大剖面圖。 第4圖是本發明的水晶體系統之第二水晶體的放大頂 面圖。 第5圖是本發明的水晶體系統之第二水晶體的放大正 視圖。 【主要元件符號說明】 1332830 10…水晶體系統 20…支撐腳 12…後側水晶體 22· · 14···前側水晶體 24…光學元件 16…周邊環 26…區域 18…周邊環帶 28···垂直側壁 19···孔洞 12

Claims (1)

1332830 第96115016號專利申請案申請專利範圍修正本 99.07.14. 十、申請專利範圍： 1. 一種調節式人工水晶體系統，其包含有 • 一第一水晶體； • 一第二水晶體，其適於相對於該第一水晶體配置，以便 5 可沿著該系統之光軸移動， 一環，其係附接至該第一水晶體，該環具有一向前突出 之側壁；以及 其中該第二水晶體包含數個支撐腳，該等支撐腳適於向 前地形成拱頂且適於配設在該側壁内， 10 其特徵在於，該等支撐腳適於自該第二水晶體螺旋狀地 形成拱頂以及適於架騎(ride)在該環之側壁内。 2. 如申請專利範圍第1項的調節式人工水晶體系統，其中 該等支撐腳係藉由鉸鏈區域而附接至該第二個水晶 體，該鉸鏈區域可以允許該第二水晶體因應該環的壓縮 15 而移動離開該第一水晶體。 3. 如申請專利範圍第1項的調節式人工水晶體系統，其中 該第一水晶體係藉由一周圍環帶而附接至該環。 4. 如申請專利範圍第2項的調節式人工水晶體系統，其中 該第一水晶體係藉由一周圍環帶而附接至該環。 20 5.如申請專利範圍第3項的調節式人工水晶體系統，其中 該周圍環帶包含數個孔洞。 ' 6.如申請專利範圍第4項的調節式人工水晶體系統，其中 該周圍環帶包含數個孔洞。 7.如申請專利範圍第1至6項任一項的調節式人工水晶體 13 1332830 系統，其中該第二水晶體包含有一軟丙烯酸材料。 8. 如申請專利範圍第1至6項任一項的調節式人工水晶體 系統，其中該第二水晶體包含一水凝膠材料。 9. 如申請專利範圍第1至6項任一項的調節式人工水晶體 5 系統，其中該第二水晶體包含一矽膠材料。 14 1332830 七、指定代表圖·· (一） 本案指定代表圖為：第（1 )圖。 (二) 本代表圖之元件符號簡單說明： 八、本案若有化學式時，請揭示最能顯示發明特徵的化學式： 10…水晶體系統 20…支撐腳 12…後側水晶體 22…視轴 14…前侧水晶體 24…光學元件 16…周邊環 26…區域 18…周邊環帶 28···垂直側壁 19···孔洞
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Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4916351B2 (ja) * 2007-03-15 2012-04-11 Ｈｏｙａ株式会社 軟性眼内レンズ
EP2305177B1 (en) * 2008-06-19 2020-12-02 Hoya Corporation Soft intraocular lens
WO2010093548A1 (en) * 2009-02-10 2010-08-19 Alcon, Inc. Accommodative intraocular lens system
US9078744B2 (en) * 2009-02-11 2015-07-14 Novartis Ag Single optic accommodative intraocular lens system
US9039762B2 (en) * 2010-03-23 2015-05-26 Novartis Ag Accommodating intraocular lens using trapezoidal phase shift
WO2011137191A1 (en) 2010-04-27 2011-11-03 Ramgopal Rao Accommodating intraocular lens device
US9220590B2 (en) 2010-06-10 2015-12-29 Z Lens, Llc Accommodative intraocular lens and method of improving accommodation
RU2459598C2 (ru) * 2010-12-01 2012-08-27 Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" Устройство для повышения ротационной стабильности торических интраокулярных линз
US9186243B2 (en) * 2011-05-31 2015-11-17 Novartis Ag Accommodative intraocular lens and method of implantation
US8900300B1 (en) 2012-02-22 2014-12-02 Omega Ophthalmics Llc Prosthetic capsular bag and method of inserting the same
US9364318B2 (en) 2012-05-10 2016-06-14 Z Lens, Llc Accommodative-disaccommodative intraocular lens
JP6061601B2 (ja) * 2012-10-03 2017-01-18 興和株式会社 眼内レンズ
US9204962B2 (en) 2013-03-13 2015-12-08 Acufocus, Inc. In situ adjustable optical mask
RU2538242C1 (ru) * 2013-08-02 2015-01-10 федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Искусственный хрусталик глаза
JP6625975B2 (ja) 2013-11-01 2019-12-25 レンスゲン、インコーポレイテッド 調節性眼内レンズデバイス
WO2015066532A1 (en) 2013-11-01 2015-05-07 Daniel Brady Two-part accommodating intraocular lens device
CA2952809C (en) 2014-06-19 2019-11-26 Omega Ophthalmics Llc Prosthetic capsular devices, systems, and methods
US10004596B2 (en) 2014-07-31 2018-06-26 Lensgen, Inc. Accommodating intraocular lens device
US11109957B2 (en) 2014-09-22 2021-09-07 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US11938018B2 (en) 2014-09-22 2024-03-26 Onpoint Vision, Inc. Intraocular pseudophakic contact lens (IOPCL) for treating age-related macular degeneration (AMD) or other eye disorders
US10299910B2 (en) 2014-09-22 2019-05-28 Kevin J. Cady Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10945832B2 (en) 2014-09-22 2021-03-16 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10159562B2 (en) 2014-09-22 2018-12-25 Kevin J. Cady Intraocular pseudophakic contact lenses and related systems and methods
EP3197462A4 (en) 2014-09-23 2018-05-30 Lensgen, Inc Polymeric material for accommodating intraocular lenses
US9358103B1 (en) 2015-02-10 2016-06-07 Omega Ophthalmics Llc Prosthetic capsular devices, systems, and methods
WO2017096087A1 (en) 2015-12-01 2017-06-08 Daniel Brady Accommodating intraocular lens device
IL245775A0 (en) 2016-05-22 2016-08-31 Joshua Ben Nun Hybrid accommodative intraocular lens
WO2017205811A1 (en) 2016-05-27 2017-11-30 Thomas Silvestrini Lens oil having a narrow molecular weight distribution for intraocular lens devices
EP3463189B1 (en) 2016-06-06 2023-01-18 Omega Ophthalmics LLC Prosthetic capsular device
EP3503843B1 (en) 2016-08-24 2023-11-15 Carl Zeiss Meditec AG Dual mode accommodative-disacommodative intraocular lens
AU2017345731B2 (en) 2016-10-21 2019-10-24 Omega Ophthalmics Llc Prosthetic capsular devices, systems, and methods
RU2683702C2 (ru) * 2017-06-21 2019-04-01 Андрей Владимирович Золотарёв Интраокулярная линза
WO2019010178A1 (en) 2017-07-05 2019-01-10 Acufocus, Inc. LENS PROTECTIVE HOLDER
WO2019195587A1 (en) 2018-04-06 2019-10-10 Omega Ophthalmics Llc Prosthetic capsular devices, systems, and methods
GB2578639A (en) 2018-11-02 2020-05-20 Rayner Intraocular Lenses Ltd Hybrid accommodating intraocular lens assemblages including discrete lens unit with segmented lens haptics
WO2021144787A1 (en) * 2020-01-13 2021-07-22 Shaare Zedek Scientific Ltd. Intraocular ring system
US11759309B2 (en) 2020-04-29 2023-09-19 Long Bridge Medical, Inc. Devices to support and position an intraocular lens within the eye and methods of use
EP4225211A1 (en) 2020-10-12 2023-08-16 Omega Ophthalmics LLC Prosthetic capsular devices, systems, and methods
US11357620B1 (en) 2021-09-10 2022-06-14 California LASIK & Eye, Inc. Exchangeable optics and therapeutics
KR20230094358A (ko) * 2021-12-21 2023-06-28 주식회사 메디버스 인공수정체 지지체 및 지지조립체

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4718906A (en) * 1986-03-11 1988-01-12 Mackool Richard J Intraocular lens
US4676792A (en) * 1986-08-26 1987-06-30 Donald Praeger Method and artificial intraocular lens device for the phakic treatment of myopia
US4842601A (en) * 1987-05-18 1989-06-27 Smith S Gregory Accommodating intraocular lens and method of implanting and using same
US4981342A (en) * 1987-09-24 1991-01-01 Allergan Inc. Multifocal birefringent lens system
US4842600A (en) * 1988-03-17 1989-06-27 Feaster Fred T Intraocular lens with variable circumference encircling haptic
CS271606B1 (en) * 1988-04-11 1990-10-12 Sulc Jiri Intraocular optical system
US5358520A (en) * 1989-04-28 1994-10-25 Nestle S.A. Supplementary intraocular lens system
AU646249B2 (en) * 1990-03-15 1994-02-17 Werner Fiala Multifocal bi-refringent lens with matched bi-refringence
US5476514A (en) * 1990-04-27 1995-12-19 Cumming; J. Stuart Accommodating intraocular lens
US6197059B1 (en) * 1990-04-27 2001-03-06 Medevec Licensing, B.V. Accomodating intraocular lens
US5326347A (en) * 1991-08-12 1994-07-05 Cumming J Stuart Intraocular implants
US5578081A (en) * 1991-11-12 1996-11-26 Henry H. McDonald Eye muscle responsive artificial lens unit
US6423094B1 (en) * 1991-11-18 2002-07-23 Faezeh M. Sarfarazi Accommodative lens formed from sheet material
US5275623A (en) * 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
US5366501A (en) * 1993-05-12 1994-11-22 Langerman David W Intraocular lens with dual 360 degree haptics
DE4403326C1 (de) * 1994-02-03 1995-06-22 Hans Reinhard Prof Dr Koch Intraokulare Linsenanordnung zur Astigmatismuskorrektur
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US5728155A (en) * 1996-01-22 1998-03-17 Quantum Solutions, Inc. Adjustable intraocular lens
US6488708B2 (en) * 1999-04-09 2002-12-03 Faezeh Sarfarazi Open chamber, elliptical, accommodative intraocular lens system
US20030060881A1 (en) * 1999-04-30 2003-03-27 Advanced Medical Optics, Inc. Intraocular lens combinations
US6616692B1 (en) 1999-04-30 2003-09-09 Advanced Medical Optics, Inc. Intraocular lens combinations
US6261321B1 (en) * 1999-09-01 2001-07-17 Robert E. Kellan Phakic or aphakic intraocular lens assembly
US6241777B1 (en) * 1999-09-01 2001-06-05 Robert E. Kellan Phakic intraocular lenses
FR2799952B1 (fr) * 1999-10-21 2001-12-14 Humanoptics Ag Implant intraoculaire
US6767363B1 (en) 1999-11-05 2004-07-27 Bausch & Lomb Surgical, Inc. Accommodating positive and negative intraocular lens system
US6797004B1 (en) * 2000-03-02 2004-09-28 Advanced Medical Optics, Inc. Holders for intraocular lenses
US6551354B1 (en) * 2000-03-09 2003-04-22 Advanced Medical Optics, Inc. Accommodating intraocular lens
US6558420B2 (en) * 2000-12-12 2003-05-06 Bausch & Lomb Incorporated Durable flexible attachment components for accommodating intraocular lens
US6464725B2 (en) * 2001-01-23 2002-10-15 Bernt Christian Skotton Two-lens adjustable intraocular lens system
US7226478B2 (en) * 2001-01-25 2007-06-05 Visiogen, Inc. Optic configuration for intraocular lens system
US6524340B2 (en) * 2001-05-23 2003-02-25 Henry M. Israel Accommodating intraocular lens assembly
US6395028B1 (en) * 2001-07-18 2002-05-28 Alcon Universal Ltd. Anterior chamber phakic lens
US7097660B2 (en) * 2001-12-10 2006-08-29 Valdemar Portney Accommodating intraocular lens
US7037338B2 (en) * 2001-12-14 2006-05-02 Toshiyuki Nagamoto Intraocular ring assembly and artificial lens kit
WO2003059196A2 (en) * 2002-01-14 2003-07-24 Advanced Medical Optics, Inc. Accommodating intraocular lens with elongated suspension structure
WO2003059208A2 (en) * 2002-01-14 2003-07-24 Advanced Medical Optics, Inc. Accommodating intraocular lens with integral capsular bag ring
US6695881B2 (en) * 2002-04-29 2004-02-24 Alcon, Inc. Accommodative intraocular lens
US7018410B1 (en) * 2002-08-05 2006-03-28 Mehdi Vazeen Accommodating intraocular lens
US6616691B1 (en) * 2003-01-10 2003-09-09 Alcon, Inc. Accommodative intraocular lens
US7238201B2 (en) * 2003-02-13 2007-07-03 Visiogen, Inc. Accommodating intraocular lens system with enhanced range of motion
US6960231B2 (en) * 2003-07-14 2005-11-01 Alcon, Inc. Intraocular lens system
JP5009623B2 (ja) * 2003-12-05 2012-08-22 イノレーン リミティド ライアビリティ カンパニー 改良された眼内レンズ
US7081134B2 (en) * 2003-12-19 2006-07-25 Walter Cukrowski Posterior chamber lens implant
US7281699B2 (en) * 2003-12-29 2007-10-16 Bausch & Lomb Incorporated Universal accommodating IOL holder for lens processing and packaging
US20070016293A1 (en) * 2005-07-18 2007-01-18 Alcon, Inc. Accommodative intraocular lens system

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RU2372053C2 (ru) 2009-11-10
US20070260308A1 (en) 2007-11-08

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