TW327175B - Process for preparing steroidal 3,5-diene-3-carboxylic acid derivatives - Google Patents

Process for preparing steroidal 3,5-diene-3-carboxylic acid derivatives

Info

Publication number
TW327175B
TW327175B TW082100820A TW82100820A TW327175B TW 327175 B TW327175 B TW 327175B TW 082100820 A TW082100820 A TW 082100820A TW 82100820 A TW82100820 A TW 82100820A TW 327175 B TW327175 B TW 327175B
Authority
TW
Taiwan
Prior art keywords
diene
carboxylic acid
acid derivatives
steroidal
preparing
Prior art date
Application number
TW082100820A
Other languages
English (en)
Chinese (zh)
Inventor
Howard Baine Neil
Fell Owzngs Franklin
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of TW327175B publication Critical patent/TW327175B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW082100820A 1992-02-07 1993-02-06 Process for preparing steroidal 3,5-diene-3-carboxylic acid derivatives TW327175B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83228092A 1992-02-07 1992-02-07

Publications (1)

Publication Number Publication Date
TW327175B true TW327175B (en) 1998-02-21

Family

ID=25261209

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082100820A TW327175B (en) 1992-02-07 1993-02-06 Process for preparing steroidal 3,5-diene-3-carboxylic acid derivatives

Country Status (23)

Country Link
EP (1) EP0643724A4 (ja)
JP (1) JPH07505140A (ja)
KR (1) KR950700319A (ja)
CN (1) CN1078475A (ja)
AP (1) AP9600790A0 (ja)
AU (1) AU666177B2 (ja)
BG (1) BG98955A (ja)
BR (1) BR9305837A (ja)
CA (1) CA2129342A1 (ja)
CZ (1) CZ188794A3 (ja)
FI (1) FI943660A0 (ja)
HU (1) HUT68303A (ja)
IL (1) IL104602A (ja)
MA (1) MA22788A1 (ja)
MX (1) MX9300676A (ja)
NO (1) NO942925L (ja)
NZ (1) NZ249382A (ja)
OA (1) OA10090A (ja)
RU (1) RU94045824A (ja)
SI (1) SI9300065A (ja)
TW (1) TW327175B (ja)
WO (1) WO1993016097A1 (ja)
ZA (1) ZA93801B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9206413D0 (en) * 1992-03-24 1992-05-06 Smithkline Beecham Corp N-t-butyl-androst-3,5-diene-17b-carboxamide-3-carboxylic acid polymorph a
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors
IL104601A0 (en) * 1992-02-07 1993-07-08 Smithkline Beecham Corp Process for the preparation of steroidal dienes

Also Published As

Publication number Publication date
CA2129342A1 (en) 1993-08-19
MX9300676A (es) 1994-07-29
NZ249382A (en) 1996-05-28
CN1078475A (zh) 1993-11-17
AU666177B2 (en) 1996-02-01
EP0643724A1 (en) 1995-03-22
HU9402303D0 (en) 1994-10-28
CZ188794A3 (en) 1994-12-15
WO1993016097A1 (en) 1993-08-19
NO942925L (no) 1994-08-08
AU3612693A (en) 1993-09-03
EP0643724A4 (en) 1995-05-10
NO942925D0 (ja) 1994-08-05
MA22788A1 (fr) 1993-10-01
OA10090A (en) 1996-12-18
BR9305837A (pt) 1997-02-18
BG98955A (bg) 1995-06-30
JPH07505140A (ja) 1995-06-08
FI943660A (fi) 1994-08-05
HUT68303A (en) 1995-06-28
FI943660A0 (fi) 1994-08-05
RU94045824A (ru) 1996-07-10
SI9300065A (en) 1993-09-30
KR950700319A (ko) 1995-01-16
IL104602A0 (en) 1993-07-08
AP9600790A0 (en) 1996-04-30
ZA93801B (en) 1993-11-05
IL104602A (en) 1997-07-13

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