EP0643724A4 - PROCESS FOR THE PREPARATION OF 3-CARBONYLANDROSTADIENE 17-CARBOXAMIDES. - Google Patents

PROCESS FOR THE PREPARATION OF 3-CARBONYLANDROSTADIENE 17-CARBOXAMIDES.

Info

Publication number
EP0643724A4
EP0643724A4 EP93904946A EP93904946A EP0643724A4 EP 0643724 A4 EP0643724 A4 EP 0643724A4 EP 93904946 A EP93904946 A EP 93904946A EP 93904946 A EP93904946 A EP 93904946A EP 0643724 A4 EP0643724 A4 EP 0643724A4
Authority
EP
European Patent Office
Prior art keywords
carbonylandrostadiene
carboxamides
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP93904946A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0643724A1 (en
Inventor
Neil Howard Baine
Franklin Fell Owings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0643724A1 publication Critical patent/EP0643724A1/en
Publication of EP0643724A4 publication Critical patent/EP0643724A4/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP93904946A 1992-02-07 1993-02-05 PROCESS FOR THE PREPARATION OF 3-CARBONYLANDROSTADIENE 17-CARBOXAMIDES. Ceased EP0643724A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US832280 1986-02-24
US83228092A 1992-02-07 1992-02-07
PCT/US1993/001068 WO1993016097A1 (en) 1992-02-07 1993-02-05 Process of preparing 3-carbonylandrostadiene 17-carboxamides

Publications (2)

Publication Number Publication Date
EP0643724A1 EP0643724A1 (en) 1995-03-22
EP0643724A4 true EP0643724A4 (en) 1995-05-10

Family

ID=25261209

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93904946A Ceased EP0643724A4 (en) 1992-02-07 1993-02-05 PROCESS FOR THE PREPARATION OF 3-CARBONYLANDROSTADIENE 17-CARBOXAMIDES.

Country Status (23)

Country Link
EP (1) EP0643724A4 (ja)
JP (1) JPH07505140A (ja)
KR (1) KR950700319A (ja)
CN (1) CN1078475A (ja)
AP (1) AP9600790A0 (ja)
AU (1) AU666177B2 (ja)
BG (1) BG98955A (ja)
BR (1) BR9305837A (ja)
CA (1) CA2129342A1 (ja)
CZ (1) CZ188794A3 (ja)
FI (1) FI943660A0 (ja)
HU (1) HUT68303A (ja)
IL (1) IL104602A (ja)
MA (1) MA22788A1 (ja)
MX (1) MX9300676A (ja)
NO (1) NO942925L (ja)
NZ (1) NZ249382A (ja)
OA (1) OA10090A (ja)
RU (1) RU94045824A (ja)
SI (1) SI9300065A (ja)
TW (1) TW327175B (ja)
WO (1) WO1993016097A1 (ja)
ZA (1) ZA93801B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9206413D0 (en) * 1992-03-24 1992-05-06 Smithkline Beecham Corp N-t-butyl-androst-3,5-diene-17b-carboxamide-3-carboxylic acid polymorph a
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors
IL104601A0 (en) * 1992-02-07 1993-07-08 Smithkline Beecham Corp Process for the preparation of steroidal dienes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
CA2129342A1 (en) 1993-08-19
MX9300676A (es) 1994-07-29
NZ249382A (en) 1996-05-28
CN1078475A (zh) 1993-11-17
AU666177B2 (en) 1996-02-01
EP0643724A1 (en) 1995-03-22
HU9402303D0 (en) 1994-10-28
CZ188794A3 (en) 1994-12-15
WO1993016097A1 (en) 1993-08-19
TW327175B (en) 1998-02-21
NO942925L (no) 1994-08-08
AU3612693A (en) 1993-09-03
NO942925D0 (ja) 1994-08-05
MA22788A1 (fr) 1993-10-01
OA10090A (en) 1996-12-18
BR9305837A (pt) 1997-02-18
BG98955A (bg) 1995-06-30
JPH07505140A (ja) 1995-06-08
FI943660A (fi) 1994-08-05
HUT68303A (en) 1995-06-28
FI943660A0 (fi) 1994-08-05
RU94045824A (ru) 1996-07-10
SI9300065A (en) 1993-09-30
KR950700319A (ko) 1995-01-16
IL104602A0 (en) 1993-07-08
AP9600790A0 (en) 1996-04-30
ZA93801B (en) 1993-11-05
IL104602A (en) 1997-07-13

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