TW279861B - - Google Patents

Info

Publication number
TW279861B
TW279861B TW083101509A TW83101509A TW279861B TW 279861 B TW279861 B TW 279861B TW 083101509 A TW083101509 A TW 083101509A TW 83101509 A TW83101509 A TW 83101509A TW 279861 B TW279861 B TW 279861B
Authority
TW
Taiwan
Prior art keywords
dihydrofuran
cyclopentene
furan
cyano
nitro
Prior art date
Application number
TW083101509A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of TW279861B publication Critical patent/TW279861B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW083101509A 1993-03-10 1994-02-22 TW279861B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93267A DK26793D0 (da) 1993-03-10 1993-03-10 Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling

Publications (1)

Publication Number Publication Date
TW279861B true TW279861B (zh) 1996-07-01

Family

ID=8091615

Family Applications (1)

Application Number Title Priority Date Filing Date
TW083101509A TW279861B (zh) 1993-03-10 1994-02-22

Country Status (19)

Country Link
US (1) US5512562A (zh)
EP (1) EP0688320B1 (zh)
JP (1) JP3779319B2 (zh)
KR (1) KR960701022A (zh)
CN (1) CN1045957C (zh)
AT (1) ATE179700T1 (zh)
AU (1) AU682494B2 (zh)
CA (1) CA2157668C (zh)
DE (1) DE69418321T2 (zh)
DK (2) DK26793D0 (zh)
ES (1) ES2133542T3 (zh)
FI (1) FI111944B (zh)
GR (1) GR3030864T3 (zh)
IL (1) IL108730A (zh)
NO (1) NO953543L (zh)
NZ (1) NZ262098A (zh)
TW (1) TW279861B (zh)
WO (1) WO1994020472A1 (zh)
ZA (1) ZA941377B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997032870A1 (fr) * 1996-03-08 1997-09-12 Synthelabo Derives de 2-aminoethyl-benzofurane, leur preparation et leur application en therapeutique
FR2745815B1 (fr) * 1996-03-08 1998-06-26 Synthelabo Derives de benzofurane, leur preparations et compositions pharmaceutiques les comprenant
FR2752840A1 (fr) * 1996-08-29 1998-03-06 Synthelabo Derives de benzothiophene, leur preparation et leur application en therapeutique
IL131670A (en) * 1997-03-12 2005-07-25 Addex Pharmaceuticals Sa Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders
US6528529B1 (en) * 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
WO2000000203A1 (en) * 1998-06-30 2000-01-06 Eli Lilly And Company Azepine derivatives having effects on serotonin related systems
WO2003006466A1 (en) 2001-07-13 2003-01-23 Pharmacia & Upjohn Company Hexahydroazepino (4, 5-g) indoles and indolines as 5-ht receptor ligands
GB0412314D0 (en) * 2004-06-02 2004-07-07 Glaxo Group Ltd Compounds
GB0414795D0 (en) * 2004-07-01 2004-08-04 Glaxo Group Ltd Compounds
CN102140100B (zh) * 2010-01-27 2014-06-11 爱博新药研发(上海)有限公司 高效抑制丙型肝炎病毒的多环化合物及其制备方法和用途
AU2013364022A1 (en) 2012-12-21 2015-07-02 Abt Holding Company Benzazepines as serotonin 5-HT2C receptor ligands and uses thereof
CN105566262B (zh) * 2016-01-11 2017-10-27 华东理工大学 苯并呋喃‑7‑烷基胺类化合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255445A (en) * 1980-03-07 1981-03-10 Smithkline Corporation 8-Hydroxy-6,7-(2-methyl-2,3-dihydrofuro)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
CA1234110A (en) * 1983-08-12 1988-03-15 Joel G. Berger Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK157925C (da) * 1985-04-22 1990-08-27 Novo Industri As 2,3,4,5-tetrahydro-1h-3-benzazepinderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
FI954229A0 (fi) 1995-09-08
ATE179700T1 (de) 1999-05-15
DE69418321D1 (de) 1999-06-10
ES2133542T3 (es) 1999-09-16
DK0688320T3 (da) 1999-11-01
CA2157668A1 (en) 1994-09-15
WO1994020472A1 (en) 1994-09-15
CN1121710A (zh) 1996-05-01
AU6138694A (en) 1994-09-26
FI954229A (fi) 1995-09-08
AU682494B2 (en) 1997-10-09
NO953543D0 (no) 1995-09-08
JP3779319B2 (ja) 2006-05-24
NZ262098A (en) 1996-11-26
EP0688320A1 (en) 1995-12-27
CA2157668C (en) 2006-05-30
ZA941377B (en) 1995-08-28
FI111944B (fi) 2003-10-15
DE69418321T2 (de) 1999-12-30
GR3030864T3 (en) 1999-11-30
IL108730A0 (en) 1994-05-30
KR960701022A (ko) 1996-02-24
NO953543L (no) 1995-09-08
US5512562A (en) 1996-04-30
JPH08507498A (ja) 1996-08-13
IL108730A (en) 1999-08-17
CN1045957C (zh) 1999-10-27
EP0688320B1 (en) 1999-05-06
DK26793D0 (da) 1993-03-10

Similar Documents

Publication Publication Date Title
TW279861B (zh)
EP1020445A4 (en) CONDENSED PYRIDE DERIVATIVES
UA66825C2 (uk) Азаполіциклічні сполуки, конденсовані з арилом, фармацевтична композиція, спосіб лікування та спосіб зниження нікотинової залежності
MY136270A (en) Processes and intermediates for preparing anti-cancer compounds
ZA982134B (en) Therapeutic agents.
TW349098B (en) Naphthalene derivatives, process for the preparation thereof, and intermediates therefor
CA2269994A1 (en) 7-hetero-bicyclo¬2.2.1|-heptanes
ES2193158T3 (es) Compuestos tetraciclicos agonistas de la dopamina.
EA200000731A1 (ru) Альфа-аминоамидные производные, полезные в качестве анальгетических агентов
ES8706159A1 (es) Procedimiento para la fabricacion de nuevos antibioticos de b-lactama
IL105464A0 (en) 1-piperazino-1,2-dihydroindene derivatives
GB9306886D0 (en) Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
BG108193A (en) Pregabalin lactose conjugates
ZA971670B (en) Aminotetralin derivatives and compositions and method of use thereof.
TR199900527T2 (xx) N�rolojik bozukluklar�n tedavisi i�in benzopiranollerin kullan�m�.
PL312251A1 (en) Isoquinoline derivatives as therapeutic agents
NZ536524A (en) Anticonvulsant and central nervous system-active bis(fluorophenyl)alkylamides
TW334428B (en) Novel benzodiazepine derivatives
AP2002002595A0 (en) Heterocyclic amide derivatives.
EP0769496A4 (en) 2,3-DIHYDROBENZOFURAN DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF
JO1815B1 (en) Therapeutic agents