GR3030864T3 - Heterocyclic compounds, their use and preparation - Google Patents

Heterocyclic compounds, their use and preparation

Info

Publication number
GR3030864T3
GR3030864T3 GR990401950T GR990401950T GR3030864T3 GR 3030864 T3 GR3030864 T3 GR 3030864T3 GR 990401950 T GR990401950 T GR 990401950T GR 990401950 T GR990401950 T GR 990401950T GR 3030864 T3 GR3030864 T3 GR 3030864T3
Authority
GR
Greece
Prior art keywords
dihydrofuran
cyclopentene
furan
cyano
nitro
Prior art date
Application number
GR990401950T
Other languages
English (en)
Inventor
Rolf Hohlweg
Erik Bardrum Nielsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of GR3030864T3 publication Critical patent/GR3030864T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR990401950T 1993-03-10 1999-07-27 Heterocyclic compounds, their use and preparation GR3030864T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93267A DK26793D0 (da) 1993-03-10 1993-03-10 Benzofuranyl- eller dihydrobenzofuranyl-substituerede tricycliske benzazepiner, der anvendelse og fremstilling
PCT/DK1994/000069 WO1994020472A1 (en) 1993-03-10 1994-02-18 Heterocyclic compounds, their use and preparation

Publications (1)

Publication Number Publication Date
GR3030864T3 true GR3030864T3 (en) 1999-11-30

Family

ID=8091615

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990401950T GR3030864T3 (en) 1993-03-10 1999-07-27 Heterocyclic compounds, their use and preparation

Country Status (19)

Country Link
US (1) US5512562A (el)
EP (1) EP0688320B1 (el)
JP (1) JP3779319B2 (el)
KR (1) KR960701022A (el)
CN (1) CN1045957C (el)
AT (1) ATE179700T1 (el)
AU (1) AU682494B2 (el)
CA (1) CA2157668C (el)
DE (1) DE69418321T2 (el)
DK (2) DK26793D0 (el)
ES (1) ES2133542T3 (el)
FI (1) FI111944B (el)
GR (1) GR3030864T3 (el)
IL (1) IL108730A (el)
NO (1) NO953543L (el)
NZ (1) NZ262098A (el)
TW (1) TW279861B (el)
WO (1) WO1994020472A1 (el)
ZA (1) ZA941377B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2745815B1 (fr) * 1996-03-08 1998-06-26 Synthelabo Derives de benzofurane, leur preparations et compositions pharmaceutiques les comprenant
JP2000506157A (ja) * 1996-03-08 2000-05-23 サンテラボ （２―アミノエチル）ベンゾフラン誘導体、その製造およびその治療的使用
FR2752840A1 (fr) * 1996-08-29 1998-03-06 Synthelabo Derives de benzothiophene, leur preparation et leur application en therapeutique
EP1011679B1 (en) * 1997-03-12 2003-07-30 Addex Pharmaceuticals SA Use of 8-nitro-2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders
US6528529B1 (en) * 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
EP1091741A4 (en) * 1998-06-30 2002-12-18 Lilly Co Eli AZEPINE DERIVATIVES PLAYING A ROLE IN SEROTONIN ASSOCIATED SYSTEMS
JP2005522408A (ja) 2001-07-13 2005-07-28 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー ５−ＨＴ受容体リガントとしてのヘキサヒドロアゼピノ（４，５−ｇ）インドールおよびインドリン
GB0412314D0 (en) 2004-06-02 2004-07-07 Glaxo Group Ltd Compounds
GB0414795D0 (en) * 2004-07-01 2004-08-04 Glaxo Group Ltd Compounds
US8653025B2 (en) * 2010-01-27 2014-02-18 AB Pharma Ltd. Polyheterocyclic compounds highly potent as HCV inhibitors
SG11201504749TA (en) 2012-12-21 2015-07-30 Abt Holding Co Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof
CN105566262B (zh) * 2016-01-11 2017-10-27 华东理工大学 苯并呋喃‑7‑烷基胺类化合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4255445A (en) * 1980-03-07 1981-03-10 Smithkline Corporation 8-Hydroxy-6,7-(2-methyl-2,3-dihydrofuro)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
CA1234110A (en) * 1983-08-12 1988-03-15 Joel G. Berger Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK157925C (da) * 1985-04-22 1990-08-27 Novo Industri As 2,3,4,5-tetrahydro-1h-3-benzazepinderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
NO953543D0 (no) 1995-09-08
DK0688320T3 (da) 1999-11-01
AU682494B2 (en) 1997-10-09
TW279861B (el) 1996-07-01
ES2133542T3 (es) 1999-09-16
CA2157668A1 (en) 1994-09-15
DK26793D0 (da) 1993-03-10
EP0688320A1 (en) 1995-12-27
FI111944B (fi) 2003-10-15
IL108730A (en) 1999-08-17
US5512562A (en) 1996-04-30
IL108730A0 (en) 1994-05-30
WO1994020472A1 (en) 1994-09-15
EP0688320B1 (en) 1999-05-06
ZA941377B (en) 1995-08-28
CA2157668C (en) 2006-05-30
FI954229A0 (fi) 1995-09-08
AU6138694A (en) 1994-09-26
NO953543L (no) 1995-09-08
NZ262098A (en) 1996-11-26
DE69418321D1 (de) 1999-06-10
KR960701022A (ko) 1996-02-24
JP3779319B2 (ja) 2006-05-24
CN1121710A (zh) 1996-05-01
DE69418321T2 (de) 1999-12-30
JPH08507498A (ja) 1996-08-13
FI954229A (fi) 1995-09-08
CN1045957C (zh) 1999-10-27
ATE179700T1 (de) 1999-05-15

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