TW251274B - - Google Patents

Info

Publication number
TW251274B
TW251274B TW082108452A TW82108452A TW251274B TW 251274 B TW251274 B TW 251274B TW 082108452 A TW082108452 A TW 082108452A TW 82108452 A TW82108452 A TW 82108452A TW 251274 B TW251274 B TW 251274B
Authority
TW
Taiwan
Prior art keywords
alkyl
aryl
hydrogen
group
dipeptide
Prior art date
Application number
TW082108452A
Other languages
English (en)
Chinese (zh)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Application granted granted Critical
Publication of TW251274B publication Critical patent/TW251274B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663Stabilised liquid enzyme compositions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06191Dipeptides containing heteroatoms different from O, S, or N
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW082108452A 1992-08-14 1993-10-13 TW251274B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/931,809 US5442100A (en) 1992-08-14 1992-08-14 β-aminoalkyl and β-N-peptidylaminoalkyl boronic acids

Publications (1)

Publication Number Publication Date
TW251274B true TW251274B (enExample) 1995-07-11

Family

ID=25461390

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082108452A TW251274B (enExample) 1992-08-14 1993-10-13

Country Status (10)

Country Link
US (2) US5442100A (enExample)
EP (1) EP0655067B1 (enExample)
JP (1) JPH08500113A (enExample)
CN (1) CN1047596C (enExample)
AT (1) ATE159945T1 (enExample)
AU (1) AU4799793A (enExample)
DE (1) DE69315079T2 (enExample)
MX (1) MX9304970A (enExample)
TW (1) TW251274B (enExample)
WO (1) WO1994004542A1 (enExample)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE149563T1 (de) * 1992-08-14 1997-03-15 Procter & Gamble Alpha-aminoborsäurehaltige flüssige waschmittel
AU7121394A (en) * 1993-07-09 1995-02-06 Borax Consolidated Ltd Boronic acid or borinic acid derivatives as enzyme stabilizers
US5834415A (en) * 1994-04-26 1998-11-10 Novo Nordisk A/S Naphthalene boronic acids
DE4422433A1 (de) * 1994-06-28 1996-01-04 Cognis Bio Umwelt Mehrenzymgranulat
US5731439A (en) * 1995-03-24 1998-03-24 The Dupont Merck Pharmaceutical Company Piperidine containing aminobornic acids
US6086634A (en) 1995-06-05 2000-07-11 Custom Cleaner, Inc. Dry-cleaning compositions containing polysulfonic acid
EP0830473A4 (en) 1995-06-05 1999-01-07 Creative Prod Resource Inc CHEMICAL CLEANING KIT FOR USE IN DRYER
US5658651A (en) 1995-09-29 1997-08-19 Creative Products Resource, Inc. Fabric treatment and softener system for in-dryer use
US6036727A (en) 1995-06-05 2000-03-14 Creative Products Resource, Inc. Anhydrous dry-cleaning compositions containing polysulfonic acid, and dry-cleaning kits for delicate fabrics
WO1996041859A1 (en) * 1995-06-13 1996-12-27 Novo Nordisk A/S 4-substituted-phenyl-boronic acids as enzyme stabilizers
IL146923A0 (en) * 1999-06-14 2002-08-14 Wisconsin Alumni Res Found Oligomers and polymers of cyclic imino carboxylic acids
CN101014691A (zh) * 2004-09-08 2007-08-08 宝洁公司 具有改善的气味的衣物处理组合物
ES2568784T5 (es) * 2008-01-04 2023-09-13 Procter & Gamble Una composición detergente para lavado de ropa que comprende glicosil hidrolasa
US20090209447A1 (en) * 2008-02-15 2009-08-20 Michelle Meek Cleaning compositions
CN102057030B (zh) 2008-06-06 2016-05-11 宝洁公司 包含家族44木葡聚糖酶变体的洗涤剂组合物
BR122014008753A2 (pt) 2008-06-17 2015-12-29 Millennium Pharm Inc compostos de éster boronato e composições farmacêuticas dos mesmos
BR112012000531A2 (pt) 2009-07-09 2019-09-24 Procter & Gamble composição detergente para lavagem de roupas catalítica que compreende teores relativamente baixos de eletrólito solúvel em água
BR112012000520A2 (pt) 2009-07-09 2016-02-16 Procter & Gamble composição catalítica detergente para lavagem de roupa que compreende teores relativamente baixos de eletrólito solúvel em água
US8933131B2 (en) 2010-01-12 2015-01-13 The Procter & Gamble Company Intermediates and surfactants useful in household cleaning and personal care compositions, and methods of making the same
CA2792767C (en) 2010-03-12 2014-07-08 The Procter & Gamble Company Ph tuneable amido-gellant for use in consumer product compositions
US8207107B2 (en) 2010-03-12 2012-06-26 The Procter & Gamble Company Di-amido gellant for use in consumer product compositions
EP2603514B1 (en) 2010-08-10 2018-07-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
WO2012138423A1 (en) 2011-02-17 2012-10-11 The Procter & Gamble Company Compositions comprising mixtures of c10-c13 alkylphenyl sulfonates
MX2013009546A (es) 2011-02-17 2013-11-22 Procter & Gamble Alquilfenil sulfonatos lineales de base biologica.
EP2737043B1 (en) 2011-07-25 2017-01-04 The Procter and Gamble Company Detergents having acceptable color
US20130303427A1 (en) 2011-09-13 2013-11-14 Susana Fernandez Prieto MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS
EP2802593A1 (en) * 2012-01-09 2014-11-19 The University of Tromsoe Therapeutic boron-containing compounds
EP2716644B1 (en) 2012-10-03 2017-04-05 The Procter and Gamble Company A stable enzyme stabilizer premix
JP2016509594A (ja) 2013-01-04 2016-03-31 レンペックス・ファーマシューティカルズ・インコーポレイテッド ボロン酸誘導体及びその治療的使用
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
CN105189724A (zh) 2013-03-14 2015-12-23 诺维信公司 含有酶和抑制剂的水溶性膜
JP7020778B2 (ja) 2013-05-03 2022-02-16 ノボザイムス アクティーゼルスカブ 洗剤酵素のマイクロカプセル化
US9687497B1 (en) 2014-05-05 2017-06-27 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
RS59488B1 (sr) 2014-05-05 2019-12-31 Rempex Pharmaceuticals Inc Sinteza boronatnih soli i njihove upotrebe
MX2016015093A (es) 2014-05-19 2017-03-27 Rempex Pharmaceuticals Inc Derivados de acido boronico y sus usos terapeuticos.
CN106659761A (zh) 2014-05-20 2017-05-10 千年药物公司 初级癌症疗法后使用的含硼蛋白酶体抑制剂
EA201692301A1 (ru) 2014-07-01 2017-06-30 Ремпекс Фармасьютикалз, Инк. Производные бороновой кислоты и их терапевтическое применение
WO2016001319A1 (en) 2014-07-03 2016-01-07 Novozymes A/S Improved stabilization of non-protease enzyme
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
WO2016097352A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Protease variants and polynucleotides encoding same
WO2016100043A1 (en) 2014-12-19 2016-06-23 Rempex Pharmaceuticals, Inc. Apparatus and continuous flow process for production of boronic acid derivatives
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
CN114292829A (zh) 2015-07-06 2022-04-08 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
BR112018007474A2 (pt) 2015-10-14 2018-10-30 Novozymes A/S ?limpeza de membranas de filtração de água?
EP3478693B1 (en) 2016-06-30 2021-07-21 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
US11078445B2 (en) 2017-05-05 2021-08-03 Novozymes A/S Compositions comprising lipase and sulfite
CN111108183A (zh) 2017-06-30 2020-05-05 诺维信公司 酶浆液组合物
JP7377545B2 (ja) 2017-10-11 2023-11-10 キューペックス バイオファーマ, インコーポレイテッド ボロン酸誘導体およびその合成
WO2019086528A1 (en) 2017-11-01 2019-05-09 Novozymes A/S Polypeptides and compositions comprising such polypeptides
EP4379029A1 (en) 2017-11-01 2024-06-05 Novozymes A/S Polypeptides and compositions comprising such polypeptides
EP3765185B1 (en) 2018-03-13 2023-07-19 Novozymes A/S Microencapsulation using amino sugar oligomers
CA3097127A1 (en) 2018-04-20 2019-10-24 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
EP3647397A1 (en) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Cleaning compositions containing dispersins iv
ES2981999T3 (es) 2018-10-31 2024-10-14 Henkel Ag & Co Kgaa Composiciones limpiadoras que contienen dispersinas V
JP7381740B2 (ja) 2019-11-27 2023-11-15 ザ プロクター アンド ギャンブル カンパニー 液体洗濯洗剤組成物
WO2021123307A2 (en) 2019-12-20 2021-06-24 Novozymes A/S Polypeptides having proteolytic activity and use thereof
US20240301328A1 (en) 2021-03-12 2024-09-12 Novozymes A/S Polypeptide variants
WO2024131880A2 (en) 2022-12-23 2024-06-27 Novozymes A/S Detergent composition comprising catalase and amylase

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872479A (en) * 1955-06-30 1959-02-03 Callery Chemical Co Preparation of organoboron compounds
US3912595A (en) * 1974-02-25 1975-10-14 Us Health Method of purifying enzymes using boronic acids covalently bonded to an insoluble support
IT1129814B (it) * 1980-07-02 1986-06-11 Unilever Nv Composizione detergente enzimatica liquida
US4462922A (en) * 1981-11-19 1984-07-31 Lever Brothers Company Enzymatic liquid detergent composition
GB8311314D0 (en) * 1983-04-26 1983-06-02 Unilever Plc Aqueous enzyme-containing compositions
US4652394A (en) * 1983-05-31 1987-03-24 Colgate Palmolive Co. Built single phase liquid anionic detergent compositions containing stabilized enzymes
DE3413571A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Verwendung von kristallinen schichtfoermigen natriumsilikaten zur wasserenthaertung und verfahren zur wasserenthaertung
US4537707A (en) * 1984-05-14 1985-08-27 The Procter & Gamble Company Liquid detergents containing boric acid and formate to stabilize enzymes
US4566985A (en) * 1984-09-19 1986-01-28 Applied Biochemists, Inc. Method of cleaning using liquid compositions comprising stabilized mixtures of enzymes
US4747977A (en) * 1984-11-09 1988-05-31 The Procter & Gamble Company Ethanol-free liquid laundry detergent compositions
US4842769A (en) * 1985-07-26 1989-06-27 Colgate-Palmolive Co. Stabilized fabric softening built detergent composition containing enzymes
US4900475A (en) * 1985-07-26 1990-02-13 Colgate-Palmolive Co. Stabilized built liquid detergent composition containing enzyme
US4933287A (en) * 1985-08-09 1990-06-12 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
EG18543A (en) * 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
US4842758A (en) * 1986-10-31 1989-06-27 Colgate-Palmolive Company Stabilized enzyme system for use in aqueous liquid built detergent compositions
US4704233A (en) * 1986-11-10 1987-11-03 The Procter & Gamble Company Detergent compositions containing ethylenediamine-N,N'-disuccinic acid
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
DK571587D0 (da) * 1987-11-02 1987-11-02 Novo Industri As Enzymatisk detergentsammensaetning
EP0315574A3 (de) * 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin-Inhibitoren
GB8810822D0 (en) * 1988-05-06 1988-06-08 Unilever Plc Liquid detergent compositions
US4963655A (en) * 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5039446A (en) * 1988-07-01 1991-08-13 Genencor International, Inc. Liquid detergent with stabilized enzyme
DE3840452A1 (de) * 1988-12-01 1990-06-07 Hoechst Ag (beta)-amino-boronsaeure-derivate
CA2006527A1 (en) * 1988-12-30 1990-06-30 Martin S. Cardinali Enzymatic liquid detergent compositions
US4959179A (en) * 1989-01-30 1990-09-25 Lever Brothers Company Stabilized enzymes liquid detergent composition containing lipase and protease
US4908150A (en) * 1989-02-02 1990-03-13 Lever Brothers Company Stabilized lipolytic enzyme-containing liquid detergent composition
EP0385401A1 (en) * 1989-02-27 1990-09-05 Occidental Chemical Corporation Unique Microbial lipases with activity at temperatures and pHs suitable for use in detergents
ATE188990T1 (de) * 1989-05-15 2000-02-15 Clorox Co Wäschewaschverfahren
EP0450702A3 (en) * 1990-04-06 1993-06-02 Unilever N.V. Process for preparing liquid enzymatic detergent compositions
EP0478050A1 (en) * 1990-09-24 1992-04-01 Unilever N.V. Detergent composition
DK0486073T3 (da) * 1990-11-14 1996-12-09 Procter & Gamble Væskeformig detergentsammensætning, der indeholder lipase og protease

Also Published As

Publication number Publication date
DE69315079T2 (de) 1998-06-04
ATE159945T1 (de) 1997-11-15
US5442100A (en) 1995-08-15
CN1090850A (zh) 1994-08-17
AU4799793A (en) 1994-03-15
WO1994004542A1 (en) 1994-03-03
DE69315079D1 (de) 1997-12-11
US5488157A (en) 1996-01-30
CN1047596C (zh) 1999-12-22
MX9304970A (es) 1994-05-31
EP0655067B1 (en) 1997-11-05
JPH08500113A (ja) 1996-01-09
EP0655067A1 (en) 1995-05-31

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