MX9304970A - ACIDOS ß-AMINOALQUIL- Y ß-N-PEPTIDILAMINOALQUIL-BORONICOS. - Google Patents
ACIDOS ß-AMINOALQUIL- Y ß-N-PEPTIDILAMINOALQUIL-BORONICOS.Info
- Publication number
- MX9304970A MX9304970A MX9304970A MX9304970A MX9304970A MX 9304970 A MX9304970 A MX 9304970A MX 9304970 A MX9304970 A MX 9304970A MX 9304970 A MX9304970 A MX 9304970A MX 9304970 A MX9304970 A MX 9304970A
- Authority
- MX
- Mexico
- Prior art keywords
- peptidylaminoalkyl
- aminoalkyl
- boronic acids
- alkyl
- aryl
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 108010016626 Dipeptides Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000006242 amine protecting group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 150000001735 carboxylic acids Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38663—Stabilised liquid enzyme compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Detergent Compositions (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/931,809 US5442100A (en) | 1992-08-14 | 1992-08-14 | β-aminoalkyl and β-N-peptidylaminoalkyl boronic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9304970A true MX9304970A (es) | 1994-05-31 |
Family
ID=25461390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9304970A MX9304970A (es) | 1992-08-14 | 1993-08-16 | ACIDOS ß-AMINOALQUIL- Y ß-N-PEPTIDILAMINOALQUIL-BORONICOS. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5442100A (enExample) |
| EP (1) | EP0655067B1 (enExample) |
| JP (1) | JPH08500113A (enExample) |
| CN (1) | CN1047596C (enExample) |
| AT (1) | ATE159945T1 (enExample) |
| AU (1) | AU4799793A (enExample) |
| DE (1) | DE69315079T2 (enExample) |
| MX (1) | MX9304970A (enExample) |
| TW (1) | TW251274B (enExample) |
| WO (1) | WO1994004542A1 (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2098484T3 (es) * | 1992-08-14 | 1997-05-01 | Procter & Gamble | Detergentes liquidos que contienen un acido alfa-amino-boronico. |
| EP0707642A1 (en) * | 1993-07-09 | 1996-04-24 | Novo Nordisk A/S | Boronic acid or borinic acid derivatives as enzyme stabilizers |
| US5834415A (en) * | 1994-04-26 | 1998-11-10 | Novo Nordisk A/S | Naphthalene boronic acids |
| DE4422433A1 (de) * | 1994-06-28 | 1996-01-04 | Cognis Bio Umwelt | Mehrenzymgranulat |
| US5731439A (en) * | 1995-03-24 | 1998-03-24 | The Dupont Merck Pharmaceutical Company | Piperidine containing aminobornic acids |
| WO1996039556A1 (en) | 1995-06-05 | 1996-12-12 | Creative Products Resource, Inc. | Dry-cleaning kit for in-dryer use |
| US6086634A (en) | 1995-06-05 | 2000-07-11 | Custom Cleaner, Inc. | Dry-cleaning compositions containing polysulfonic acid |
| US6036727A (en) | 1995-06-05 | 2000-03-14 | Creative Products Resource, Inc. | Anhydrous dry-cleaning compositions containing polysulfonic acid, and dry-cleaning kits for delicate fabrics |
| US5658651A (en) | 1995-09-29 | 1997-08-19 | Creative Products Resource, Inc. | Fabric treatment and softener system for in-dryer use |
| EP0832174B1 (en) * | 1995-06-13 | 2002-05-08 | Novozymes A/S | 4-substituted-phenyl-boronic acids as enzyme stabilizers |
| ATE509912T1 (de) * | 1999-06-14 | 2011-06-15 | Wisconsin Alumni Res Found | Oligomere und polymere von zyklischen imino- carbonsäuren |
| US20060063690A1 (en) * | 2004-09-08 | 2006-03-23 | Billiauw Jan Julien M | Laundry treatment compositions with improved odor |
| EP2242831B2 (en) | 2008-01-04 | 2023-05-17 | The Procter & Gamble Company | A laundry detergent composition comprising glycosyl hydrolase |
| US20090209447A1 (en) | 2008-02-15 | 2009-08-20 | Michelle Meek | Cleaning compositions |
| HUE042847T2 (hu) | 2008-06-06 | 2019-07-29 | Procter & Gamble | A 44 xiloglukanáz család egyik variánsát tartalmazó felületaktív készítmény |
| DK2730581T3 (en) * | 2008-06-17 | 2016-08-15 | Millennium Pharm Inc | Boronate Ester Compounds and Pharmaceutical Compositions thereof. |
| EP2451914A1 (en) | 2009-07-09 | 2012-05-16 | The Procter & Gamble Company | A catalytic laundry detergent composition comprising relatively low levels of water-soluble electrolyte |
| BR112012000520A2 (pt) | 2009-07-09 | 2016-02-16 | Procter & Gamble | composição catalítica detergente para lavagem de roupa que compreende teores relativamente baixos de eletrólito solúvel em água |
| US20110166370A1 (en) | 2010-01-12 | 2011-07-07 | Charles Winston Saunders | Scattered Branched-Chain Fatty Acids And Biological Production Thereof |
| CA2791251C (en) | 2010-03-12 | 2014-08-12 | The Procter & Gamble Company | Fluid detergent compositions comprising a di-amido gellant, and processes for making |
| BR112012023054A2 (pt) | 2010-03-12 | 2017-07-25 | Procter & Gamble | composições detergentes líquidas que compreendem amido-gelificantes de ph sintonizável, e processos para a fabricação das mesmas |
| KR102205755B1 (ko) | 2010-08-10 | 2021-01-22 | 렘펙스 파머수티클스 인코퍼레이티드 | 고리형 보론산 에스터 유도체의 결정 형태 |
| RU2013136501A (ru) | 2011-02-17 | 2015-03-27 | Дзе Проктер Энд Гэмбл Компани | Линейные алкилфенилсульфонаты на основе биологического сырья |
| BR112013019685A2 (pt) | 2011-02-17 | 2016-10-18 | Procter & Gamble | composições que compreendem misturas de alquil-fenil sulfonatos c10-c13 |
| US8921299B2 (en) | 2011-07-25 | 2014-12-30 | The Procter & Gamble Company | Detergents having acceptable color |
| US20130303427A1 (en) | 2011-09-13 | 2013-11-14 | Susana Fernandez Prieto | MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS |
| CA2862710A1 (en) * | 2012-01-09 | 2013-07-18 | University Of Tromso | Therapeutic boron-containing compounds |
| EP2716644B1 (en) | 2012-10-03 | 2017-04-05 | The Procter and Gamble Company | A stable enzyme stabilizer premix |
| JP2016509594A (ja) | 2013-01-04 | 2016-03-31 | レンペックス・ファーマシューティカルズ・インコーポレイテッド | ボロン酸誘導体及びその治療的使用 |
| US9241947B2 (en) | 2013-01-04 | 2016-01-26 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| CN105189724A (zh) | 2013-03-14 | 2015-12-23 | 诺维信公司 | 含有酶和抑制剂的水溶性膜 |
| US20160075976A1 (en) | 2013-05-03 | 2016-03-17 | Novozymes A/S | Microencapsulation of Detergent Enzymes |
| FI3604316T3 (fi) | 2014-05-05 | 2024-02-29 | Melinta Therapeutics Inc | Boronaattisuolojen synteesi |
| US9687497B1 (en) | 2014-05-05 | 2017-06-27 | Rempex Pharmaceuticals, Inc. | Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof |
| AU2015264418A1 (en) | 2014-05-19 | 2016-11-10 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| AU2015264272A1 (en) | 2014-05-20 | 2016-11-24 | Millennium Pharmaceuticals, Inc. | Boron-containing proteasome inhibitors for use after primary cancer therapy |
| EA201692301A1 (ru) | 2014-07-01 | 2017-06-30 | Ремпекс Фармасьютикалз, Инк. | Производные бороновой кислоты и их терапевтическое применение |
| US20170121646A1 (en) | 2014-07-03 | 2017-05-04 | Novozymes A/S | Improved Stabilization of Non-Protease Enzyme |
| WO2016081297A1 (en) | 2014-11-18 | 2016-05-26 | Rempex Pharmaceuticals, Inc. | Cyclic boronic acid ester derivatives and therapeutic uses thereof |
| DK3234093T3 (da) | 2014-12-19 | 2020-08-17 | Novozymes As | Proteasevarianter og polynukleotider, som koder for dem |
| CN107207537B (zh) | 2014-12-19 | 2019-05-31 | 莱姆派克斯制药公司 | 用于生产硼酸衍生物的设备和连续流方法 |
| US20180051041A1 (en) | 2015-03-17 | 2018-02-22 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| WO2017005816A1 (en) | 2015-07-06 | 2017-01-12 | Novozymes A/S | Lipase variants and polynucleotides encoding same |
| CN108367251A (zh) | 2015-10-14 | 2018-08-03 | 诺维信公司 | 滤水膜的清洁 |
| UA124464C2 (uk) | 2016-06-30 | 2021-09-22 | Кьюпекс Біофарма, Інк. | Похідні боронової кислоти та їх терапевтичні застосування |
| CN120005686A (zh) | 2017-05-05 | 2025-05-16 | 诺维信公司 | 包含脂肪酶和亚硫酸根的组合物 |
| CN111108183A (zh) | 2017-06-30 | 2020-05-05 | 诺维信公司 | 酶浆液组合物 |
| EP3694864B1 (en) | 2017-10-11 | 2025-03-05 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis thereof |
| CN111479919A (zh) | 2017-11-01 | 2020-07-31 | 诺维信公司 | 多肽以及包含此类多肽的组合物 |
| EP4379029A1 (en) | 2017-11-01 | 2024-06-05 | Novozymes A/S | Polypeptides and compositions comprising such polypeptides |
| CN111770788B (zh) | 2018-03-13 | 2023-07-25 | 诺维信公司 | 使用氨基糖低聚物进行微囊化 |
| WO2019204419A1 (en) | 2018-04-20 | 2019-10-24 | The Medicines Company (San Diego), Llc | Boronic acid derivatives and therapeutic uses thereof |
| EP3647398B1 (en) | 2018-10-31 | 2024-05-15 | Henkel AG & Co. KGaA | Cleaning compositions containing dispersins v |
| EP3647397A1 (en) | 2018-10-31 | 2020-05-06 | Henkel AG & Co. KGaA | Cleaning compositions containing dispersins iv |
| EP4065677B1 (en) | 2019-11-27 | 2024-11-20 | The Procter & Gamble Company | Improved alkylbenzenesulfonate surfactants |
| EP4077656A2 (en) | 2019-12-20 | 2022-10-26 | Novozymes A/S | Polypeptides having proteolytic activity and use thereof |
| AU2021266715A1 (en) | 2020-05-05 | 2022-11-17 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof |
| US20240301328A1 (en) | 2021-03-12 | 2024-09-12 | Novozymes A/S | Polypeptide variants |
| CN120344647A (zh) | 2022-12-23 | 2025-07-18 | 诺维信公司 | 包含过氧化氢酶和淀粉酶的洗涤剂组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2872479A (en) * | 1955-06-30 | 1959-02-03 | Callery Chemical Co | Preparation of organoboron compounds |
| US3912595A (en) * | 1974-02-25 | 1975-10-14 | Us Health | Method of purifying enzymes using boronic acids covalently bonded to an insoluble support |
| IT1129814B (it) * | 1980-07-02 | 1986-06-11 | Unilever Nv | Composizione detergente enzimatica liquida |
| US4462922A (en) * | 1981-11-19 | 1984-07-31 | Lever Brothers Company | Enzymatic liquid detergent composition |
| GB8311314D0 (en) * | 1983-04-26 | 1983-06-02 | Unilever Plc | Aqueous enzyme-containing compositions |
| US4652394A (en) * | 1983-05-31 | 1987-03-24 | Colgate Palmolive Co. | Built single phase liquid anionic detergent compositions containing stabilized enzymes |
| DE3413571A1 (de) * | 1984-04-11 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verwendung von kristallinen schichtfoermigen natriumsilikaten zur wasserenthaertung und verfahren zur wasserenthaertung |
| US4537707A (en) * | 1984-05-14 | 1985-08-27 | The Procter & Gamble Company | Liquid detergents containing boric acid and formate to stabilize enzymes |
| US4566985A (en) * | 1984-09-19 | 1986-01-28 | Applied Biochemists, Inc. | Method of cleaning using liquid compositions comprising stabilized mixtures of enzymes |
| US4747977A (en) * | 1984-11-09 | 1988-05-31 | The Procter & Gamble Company | Ethanol-free liquid laundry detergent compositions |
| US4842769A (en) * | 1985-07-26 | 1989-06-27 | Colgate-Palmolive Co. | Stabilized fabric softening built detergent composition containing enzymes |
| US4900475A (en) * | 1985-07-26 | 1990-02-13 | Colgate-Palmolive Co. | Stabilized built liquid detergent composition containing enzyme |
| JPH0697997B2 (ja) * | 1985-08-09 | 1994-12-07 | ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ | 新規の酵素的洗浄剤添加物 |
| EG18543A (en) * | 1986-02-20 | 1993-07-30 | Albright & Wilson | Protected enzyme systems |
| US4842758A (en) * | 1986-10-31 | 1989-06-27 | Colgate-Palmolive Company | Stabilized enzyme system for use in aqueous liquid built detergent compositions |
| US4704233A (en) * | 1986-11-10 | 1987-11-03 | The Procter & Gamble Company | Detergent compositions containing ethylenediamine-N,N'-disuccinic acid |
| US5187157A (en) * | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| DK571587D0 (da) * | 1987-11-02 | 1987-11-02 | Novo Industri As | Enzymatisk detergentsammensaetning |
| EP0315574A3 (de) * | 1987-11-05 | 1990-08-22 | Hoechst Aktiengesellschaft | Renin-Inhibitoren |
| GB8810822D0 (en) * | 1988-05-06 | 1988-06-08 | Unilever Plc | Liquid detergent compositions |
| US4963655A (en) * | 1988-05-27 | 1990-10-16 | Mayo Foundation For Medical Education And Research | Boron analogs of amino acid/peptide protease inhibitors |
| US5039446A (en) * | 1988-07-01 | 1991-08-13 | Genencor International, Inc. | Liquid detergent with stabilized enzyme |
| DE3840452A1 (de) * | 1988-12-01 | 1990-06-07 | Hoechst Ag | (beta)-amino-boronsaeure-derivate |
| AU4724989A (en) * | 1988-12-30 | 1990-07-05 | Unilever Plc | Enzymatic liquid detergent composition |
| US4959179A (en) * | 1989-01-30 | 1990-09-25 | Lever Brothers Company | Stabilized enzymes liquid detergent composition containing lipase and protease |
| US4908150A (en) * | 1989-02-02 | 1990-03-13 | Lever Brothers Company | Stabilized lipolytic enzyme-containing liquid detergent composition |
| JPH0343073A (ja) * | 1989-02-27 | 1991-02-25 | Occidental Chem Corp | 種々の温度で活性を有する特異な微生物リパーゼ及び該リパーゼを含有する洗剤 |
| EP0399681B1 (en) * | 1989-05-15 | 2000-01-19 | The Clorox Company | Method of laundering fabrics |
| EP0450702A3 (en) * | 1990-04-06 | 1993-06-02 | Unilever N.V. | Process for preparing liquid enzymatic detergent compositions |
| EP0478050A1 (en) * | 1990-09-24 | 1992-04-01 | Unilever N.V. | Detergent composition |
| DE69121059T2 (de) * | 1990-11-14 | 1997-03-06 | The Procter & Gamble Co., Cincinnati, Ohio | Lipase- und proteasehaltige flüssige Waschmittelzusammensetzung |
-
1992
- 1992-08-14 US US07/931,809 patent/US5442100A/en not_active Expired - Fee Related
-
1993
- 1993-08-03 DE DE69315079T patent/DE69315079T2/de not_active Expired - Fee Related
- 1993-08-03 AU AU47997/93A patent/AU4799793A/en not_active Abandoned
- 1993-08-03 AT AT93918597T patent/ATE159945T1/de not_active IP Right Cessation
- 1993-08-03 EP EP93918597A patent/EP0655067B1/en not_active Expired - Lifetime
- 1993-08-03 JP JP6506312A patent/JPH08500113A/ja active Pending
- 1993-08-03 WO PCT/US1993/007276 patent/WO1994004542A1/en not_active Ceased
- 1993-08-14 CN CN93117839A patent/CN1047596C/zh not_active Expired - Fee Related
- 1993-08-16 MX MX9304970A patent/MX9304970A/es not_active IP Right Cessation
- 1993-10-13 TW TW082108452A patent/TW251274B/zh active
-
1995
- 1995-05-04 US US08/434,901 patent/US5488157A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0655067A1 (en) | 1995-05-31 |
| WO1994004542A1 (en) | 1994-03-03 |
| US5442100A (en) | 1995-08-15 |
| DE69315079T2 (de) | 1998-06-04 |
| AU4799793A (en) | 1994-03-15 |
| CN1047596C (zh) | 1999-12-22 |
| TW251274B (enExample) | 1995-07-11 |
| CN1090850A (zh) | 1994-08-17 |
| US5488157A (en) | 1996-01-30 |
| ATE159945T1 (de) | 1997-11-15 |
| DE69315079D1 (de) | 1997-12-11 |
| EP0655067B1 (en) | 1997-11-05 |
| JPH08500113A (ja) | 1996-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |