TW224098B - - Google Patents
Info
- Publication number
- TW224098B TW224098B TW082101987A TW82101987A TW224098B TW 224098 B TW224098 B TW 224098B TW 082101987 A TW082101987 A TW 082101987A TW 82101987 A TW82101987 A TW 82101987A TW 224098 B TW224098 B TW 224098B
- Authority
- TW
- Taiwan
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/856,611 US5196424A (en) | 1992-03-24 | 1992-03-24 | N-[2-amino-4-substituted[[(pyrrollo or pyrido)[2,3-d]pyrimidinyl]-alkyl]benzoyl]-L-glutamic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW224098B true TW224098B (cg-RX-API-DMAC7.html) | 1994-05-21 |
Family
ID=25324069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082101987A TW224098B (cg-RX-API-DMAC7.html) | 1992-03-24 | 1993-03-18 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5196424A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0567223A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPH0625246A (cg-RX-API-DMAC7.html) |
| KR (1) | KR930019676A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1078235A (cg-RX-API-DMAC7.html) |
| AU (1) | AU3542993A (cg-RX-API-DMAC7.html) |
| BR (1) | BR9301273A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2091978A1 (cg-RX-API-DMAC7.html) |
| CZ (1) | CZ44093A3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI931251A7 (cg-RX-API-DMAC7.html) |
| HU (1) | HUT70036A (cg-RX-API-DMAC7.html) |
| IL (1) | IL105100A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX9301544A (cg-RX-API-DMAC7.html) |
| MY (1) | MY131322A (cg-RX-API-DMAC7.html) |
| NO (1) | NO931008L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ247193A (cg-RX-API-DMAC7.html) |
| TW (1) | TW224098B (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA931944B (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5457056A (en) * | 1993-07-06 | 1995-10-10 | Fiberchem, Inc. | Halohydrocarbon sensing chemistry with base modifier |
| US6537999B2 (en) * | 1996-06-06 | 2003-03-25 | Duquesne University Of The Holy Ghost | Pyrimidine derivatives and methods of making and using these derivatives |
| AU4163197A (en) * | 1996-08-30 | 1998-03-19 | Eli Lilly And Company | Nonclassical pyrrolo{2,3-d}pyrimidine antifolates |
| JP4202250B2 (ja) | 2001-07-25 | 2008-12-24 | バイオマリン ファーマシューティカル インコーポレイテッド | 血液脳関門輸送を調節するための組成物および方法 |
| US8030319B2 (en) * | 2005-02-10 | 2011-10-04 | Duquesne University Of The Holy Ghost | Methods for treating cancer and other pathological proliferating disorders by inhibiting mitosis using pyrrolo[2 3-d]pyrimidines |
| CA2789097C (en) | 2005-04-28 | 2017-02-21 | Proteus Digital Health, Inc. | Pharma-informatics system |
| CN1962658B (zh) * | 2005-11-10 | 2010-05-12 | 北京大学 | 一种四氢吡啶并[3,2-d]嘧啶类化合物及制备抗肿瘤药物的用途 |
| WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| AU2010216512B2 (en) | 2009-02-20 | 2016-06-30 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| JP2012526144A (ja) | 2009-05-06 | 2012-10-25 | ラボラトリー スキン ケア インコーポレイテッド | 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法 |
| KR20120103604A (ko) * | 2009-11-06 | 2012-09-19 | 첼시 쎄라퓨틱스, 인코포레이티드 | 효소 저해성 화합물 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN102977107B (zh) * | 2012-12-25 | 2015-04-22 | 山西普德药业股份有限公司 | 一种培美曲塞二钠化合物及其组合物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59170091A (ja) * | 1983-03-17 | 1984-09-26 | Takeda Chem Ind Ltd | ６−チオ−７−デアザプリン誘導体およびその製造法 |
| DE3472258D1 (de) * | 1983-03-17 | 1988-07-28 | Takeda Chemical Industries Ltd | Thiodeazapurine derivatives |
| JPS61500845A (ja) * | 1983-12-27 | 1986-05-01 | エス・ア−ル・アイ・インタ−ナシヨナル | ８，１０―ジデアザミノプテリン及び抗白血病剤組成物 |
| ZA861235B (en) * | 1985-03-08 | 1986-10-29 | Univ Princeton | Pyrido(2,3-d)pyrimidine derivatives |
| US4684653A (en) * | 1985-03-08 | 1987-08-04 | The Trustees Of Princeton University | Pyrido(2,3-d)pyrimidine derivatives |
| US4927828A (en) * | 1985-03-08 | 1990-05-22 | The Trustees Of Princeton University | Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives |
| US5026851A (en) * | 1985-03-08 | 1991-06-25 | The Trustees Of Princeton University | Pyrido[2,3-]pyrimidine derivatives |
| US4923872A (en) * | 1986-08-26 | 1990-05-08 | Warner-Lambert Co. | Analogues of pyrrolo[3,2d]pyrimidin-4-ones |
| US4988702A (en) * | 1986-08-26 | 1991-01-29 | Warner-Lambert Company | Novel 9-deazaguanines |
| US4902796A (en) * | 1986-10-20 | 1990-02-20 | The Trustees Of Princeton University | 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines |
| US4988813A (en) * | 1986-10-20 | 1991-01-29 | The Trustees Of Princeton University | Process for the preparation of fused pyridine compounds |
| US4921858A (en) * | 1986-10-24 | 1990-05-01 | Warner-Lambert Company | 7-deazaguanines as immunomodulators |
| JP2830008B2 (ja) * | 1988-04-01 | 1998-12-02 | 武田薬品工業株式会社 | 縮合ピリミジン誘導体 |
| NO169490C (no) * | 1988-03-24 | 1992-07-01 | Takeda Chemical Industries Ltd | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolopyrimidinderivater |
| US4882333A (en) * | 1988-05-25 | 1989-11-21 | The Trustess Of Princeton University | N-(5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives |
| CH677140A5 (cg-RX-API-DMAC7.html) * | 1988-10-11 | 1991-04-15 | W & E Umwelttechnik Ag | |
| KR970009225B1 (ko) * | 1989-09-19 | 1997-06-09 | 데이진 가부시끼가이샤 | 피롤로[2,3-디] 피리미딘 유도체, 그의 제조방법 및 그것을 유효성분으로 하는 의약제제 |
| CA2032695A1 (en) * | 1989-12-20 | 1991-06-21 | Hiroshi Akimoto | Condensed heterocyclic compounds, their production and use |
-
1992
- 1992-03-24 US US07/856,611 patent/US5196424A/en not_active Expired - Fee Related
-
1993
- 1993-03-18 NZ NZ247193A patent/NZ247193A/en unknown
- 1993-03-18 EP EP93302063A patent/EP0567223A1/en not_active Withdrawn
- 1993-03-18 MY MYPI93000474A patent/MY131322A/en unknown
- 1993-03-18 CA CA002091978A patent/CA2091978A1/en not_active Abandoned
- 1993-03-18 IL IL105100A patent/IL105100A0/xx unknown
- 1993-03-18 CZ CZ93440A patent/CZ44093A3/cs unknown
- 1993-03-18 TW TW082101987A patent/TW224098B/zh active
- 1993-03-18 ZA ZA931944A patent/ZA931944B/xx unknown
- 1993-03-19 MX MX9301544A patent/MX9301544A/es unknown
- 1993-03-19 HU HU9300804A patent/HUT70036A/hu unknown
- 1993-03-19 NO NO93931008A patent/NO931008L/no unknown
- 1993-03-22 KR KR1019930004440A patent/KR930019676A/ko not_active Withdrawn
- 1993-03-22 FI FI931251A patent/FI931251A7/fi not_active Application Discontinuation
- 1993-03-23 BR BR9301273A patent/BR9301273A/pt not_active Application Discontinuation
- 1993-03-23 CN CN93103205A patent/CN1078235A/zh not_active Withdrawn
- 1993-03-23 AU AU35429/93A patent/AU3542993A/en not_active Abandoned
- 1993-03-23 JP JP5063819A patent/JPH0625246A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI931251L (fi) | 1993-09-25 |
| NO931008D0 (no) | 1993-03-19 |
| MX9301544A (es) | 1994-07-29 |
| ZA931944B (en) | 1994-09-18 |
| US5196424A (en) | 1993-03-23 |
| NO931008L (no) | 1993-09-27 |
| HUT70036A (en) | 1995-09-28 |
| HU9300804D0 (en) | 1993-06-28 |
| IL105100A0 (en) | 1993-12-28 |
| MY131322A (en) | 2007-08-30 |
| FI931251A7 (fi) | 1993-09-25 |
| FI931251A0 (fi) | 1993-03-22 |
| CA2091978A1 (en) | 1993-09-25 |
| NZ247193A (en) | 1995-05-26 |
| JPH0625246A (ja) | 1994-02-01 |
| KR930019676A (ko) | 1993-10-18 |
| EP0567223A1 (en) | 1993-10-27 |
| AU3542993A (en) | 1993-09-30 |
| BR9301273A (pt) | 1993-09-28 |
| CN1078235A (zh) | 1993-11-10 |
| CZ44093A3 (en) | 1994-02-16 |