TW218025B - - Google Patents

Info

Publication number
TW218025B
TW218025B TW080106046A TW80106046A TW218025B TW 218025 B TW218025 B TW 218025B TW 080106046 A TW080106046 A TW 080106046A TW 80106046 A TW80106046 A TW 80106046A TW 218025 B TW218025 B TW 218025B
Authority
TW
Taiwan
Application number
TW080106046A
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909016882A external-priority patent/GB9016882D0/en
Priority claimed from GB909016840A external-priority patent/GB9016840D0/en
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Application granted granted Critical
Publication of TW218025B publication Critical patent/TW218025B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/88—Post-polymerisation treatment
    • C08G63/90—Purification; Drying
TW080106046A 1990-08-01 1991-08-02 TW218025B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909016882A GB9016882D0 (en) 1990-08-01 1990-08-01 Improvements in or relating to organic compounds
GB909016840A GB9016840D0 (en) 1990-08-01 1990-08-01 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
TW218025B true TW218025B (zh) 1993-12-21

Family

ID=26297417

Family Applications (2)

Application Number Title Priority Date Filing Date
TW080106046A TW218025B (zh) 1990-08-01 1991-08-02
TW082100731A TW282477B (zh) 1990-08-01 1991-08-02

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW082100731A TW282477B (zh) 1990-08-01 1991-08-02

Country Status (27)

Country Link
EP (2) EP0816413B1 (zh)
JP (1) JP3137368B2 (zh)
KR (1) KR100255904B1 (zh)
AT (1) AT402503B (zh)
AU (1) AU650277B2 (zh)
CA (1) CA2048200C (zh)
CH (1) CH683772A5 (zh)
CY (1) CY1986A (zh)
DE (1) DE4124468B4 (zh)
DK (2) DK0469520T3 (zh)
ES (2) ES2243966T3 (zh)
FI (2) FI108040B (zh)
FR (1) FR2665453B1 (zh)
GB (1) GB2246573B (zh)
GR (1) GR3026322T3 (zh)
HK (1) HK11797A (zh)
HU (1) HUT59837A (zh)
IE (1) IE66185B1 (zh)
IL (1) IL99007A (zh)
IT (1) IT1252944B (zh)
LU (1) LU87985A1 (zh)
MY (1) MY108621A (zh)
NO (1) NO912960D0 (zh)
NZ (1) NZ239184A (zh)
PH (1) PH31047A (zh)
PT (1) PT98491B (zh)
TW (2) TW218025B (zh)

Families Citing this family (34)

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US5560929A (en) * 1986-08-18 1996-10-01 The Dow Chemical Company Structured copolymers and their use as absorbents, gels and carriers of metal ions
US5527524A (en) * 1986-08-18 1996-06-18 The Dow Chemical Company Dense star polymer conjugates
US5225521A (en) * 1991-12-31 1993-07-06 E. I. Du Pont De Nemours And Company Star-shaped hydroxyacid polymers
US6200558B1 (en) 1993-09-14 2001-03-13 The United States Of America As Represented By The Department Of Health And Human Services Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US5525357A (en) * 1992-08-24 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US5405919A (en) * 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
JPH06116381A (ja) * 1992-10-09 1994-04-26 Mitsui Toatsu Chem Inc ポリヒドロキシカルボン酸の精製方法
DE4412317A1 (de) * 1993-04-21 1994-10-27 Basf Ag Polylactid mit verbreiterter Molmassenverteilung
US5359026A (en) * 1993-07-30 1994-10-25 Cargill, Incorporated Poly(lactide) copolymer and process for manufacture thereof
US5496923A (en) * 1993-09-20 1996-03-05 Mitsui Toatsu Chemicals, Inc. Purification process of aliphatic polyester
CZ293764B6 (cs) * 1993-11-19 2004-07-14 Janssen Pharmaceutica N. V. Farmaceutický prostředek s dostatečným a dlouhodobým uvolňováním léčiva, biodegradovatelné a biokompatibilní mikročástice, způsob jejich výroby a použití
KR100357839B1 (ko) * 1994-03-07 2003-08-02 더 다우 케미칼 캄파니 생체활성및/또는표적화된덴드리머콘쥬게이트
ATE228021T1 (de) 1998-09-11 2002-12-15 Gerhard Dr Schmidmaier Biologisch aktive implantate
US6362308B1 (en) 2000-08-10 2002-03-26 Alkermes Controlled Therapeutics Inc. Ii Acid end group poly(d,l-lactide-co-glycolide) copolymers high glycolide content
ATE388182T1 (de) * 2001-07-10 2008-03-15 Kureha Corp Polyhydroxycarbonsäure und verfahren zu dessen herstellung
FR2830448B1 (fr) * 2001-10-10 2004-03-19 Pf Medicament Microspheres biodegradables a liberation prolongee et leur procede de preparation
ES2541908T3 (es) 2001-10-10 2015-07-28 Pierre Fabre Medicament Microesferas biodegradables de liberación prolongada y su procedimiento de preparación
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
AU2013204972B2 (en) * 2002-11-19 2016-04-21 Novartis Ag Pharmaceutical composition comprising octreotide microparticles
GB0226993D0 (en) * 2002-11-19 2002-12-24 Novartis Ag Organic compounds
SI1787658T1 (sl) 2005-11-10 2012-07-31 Chemi Spa Formulacije z trajnim sproščanjem somatostatin analognih inhibitorjev rastnega hormona
CN101193531B (zh) 2006-11-29 2010-12-01 富准精密工业(深圳)有限公司 散热装置
JP5576291B2 (ja) * 2007-12-31 2014-08-20 サムヤン バイオファーマシューティカルズ コーポレイション ポリ（α−ヒドロキシ酸）の疎水性高分子ブロックを含む高純度の両親媒性ブロック共重合体及びその製造方法
US20100256746A1 (en) * 2009-03-23 2010-10-07 Micell Technologies, Inc. Biodegradable polymers
JP5594996B2 (ja) 2009-09-14 2014-09-24 三菱重工業株式会社 航空機の操縦システム
US8722845B2 (en) 2010-06-21 2014-05-13 Lg Chem, Ltd. Polylactide resin having excellent heat resistance and preparation method thereof
EP2455414A1 (de) * 2010-11-17 2012-05-23 Evonik Röhm GmbH Verfahren zur Herstellung von hochmolekularen, resorbierbaren Polyestern, die mit dem Verfahren herstellbaren hochmolekularen resorbierbaren Polyester und deren Verwendung
EP2455415A1 (de) * 2010-11-17 2012-05-23 Evonik Röhm GmbH Verfahren zur Herstellung von niedermolekularen, resorbierbaren Polyestern, die mit dem Verfahren herstellbaren niedermolekularen resorbierbaren Polyester und deren Verwendung
CN105820332B (zh) * 2015-01-09 2018-06-29 北京化工大学 一种星形聚氨基酸和星形聚氨基酸载药纳米胶束及制备方法
EP3408305B1 (en) 2016-01-29 2024-03-06 Tolmar Inc. Purification and decolorization of polymers
SG11202001688WA (en) * 2017-08-31 2020-03-30 Evonik Corp Improved resorbable polymer purification process
GR1009392B (el) * 2017-09-19 2018-10-25 Φαρματεν Αβεε Φαρμακευτικο σκευασμα που περιλαμβανει ενα πεπτιδικο φαρμακο και μεθοδος για την παρασκευη αυτου
GB2568526A (en) * 2017-11-20 2019-05-22 Rebio Tech Oy Composition
CN112940234B (zh) * 2021-01-28 2022-05-03 广东粤港澳大湾区黄埔材料研究院 一种高纯度聚乙丙交酯的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1467970A (en) * 1975-05-02 1977-03-23 Ici Ltd Purification of polyethers
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
CA1256638A (en) * 1984-07-06 1989-06-27 Motoaki Tanaka Polymer and its production
US4677231A (en) * 1984-11-13 1987-06-30 Asahi Kasei Kogyo Kabushiki Kaisha Process for purification of polyether
JP2551756B2 (ja) * 1985-05-07 1996-11-06 武田薬品工業株式会社 ポリオキシカルボン酸エステルおよびその製造法
JPH0610252B2 (ja) * 1985-08-21 1994-02-09 和光純薬工業株式会社 重合体の製造法
DE3641692A1 (de) * 1986-12-06 1988-06-09 Boehringer Ingelheim Kg Katalysatorfreie resorbierbare homopolymere und copolymere
DE3708916A1 (de) * 1987-03-19 1988-09-29 Boehringer Ingelheim Kg Verfahren zur reinigung resorbierbarer polyester
JP2714454B2 (ja) * 1988-11-07 1998-02-16 三井東圧化学株式会社 生体吸収性ポリエステルの製造方法
DE69129770T2 (de) * 1990-04-13 1998-11-19 Takeda Chemical Industries Ltd Biologisch abbaubare hochmolekulare Polymere, ihre Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
IT1252944B (it) 1995-07-05
HK11797A (en) 1997-02-14
NZ239184A (en) 1994-09-27
CH683772A5 (de) 1994-05-13
FR2665453A1 (fr) 1992-02-07
KR920003990A (ko) 1992-03-27
GB2246573B (en) 1994-05-11
GB2246573A (en) 1992-02-05
IE66185B1 (en) 1995-12-13
KR100255904B1 (ko) 2000-05-01
HU912452D0 (en) 1991-12-30
FR2665453B1 (fr) 1995-01-27
DK0816413T3 (da) 2005-08-29
FI108040B (fi) 2001-11-15
CY1986A (en) 1997-09-05
EP0816413A3 (en) 1998-11-11
ES2243966T3 (es) 2005-12-01
AU650277B2 (en) 1994-06-16
DE4124468A1 (de) 1992-02-06
ITRM910553A1 (it) 1993-01-23
TW282477B (zh) 1996-08-01
EP0469520A3 (en) 1992-10-07
EP0469520B1 (en) 1998-02-25
PT98491A (pt) 1992-06-30
EP0816413A2 (en) 1998-01-07
FI913641A0 (fi) 1991-07-30
NO912960D0 (no) 1991-07-30
GR3026322T3 (en) 1998-06-30
LU87985A1 (fr) 1993-02-15
CA2048200C (en) 1999-06-29
EP0469520A2 (en) 1992-02-05
PH31047A (en) 1998-02-03
GB9116396D0 (en) 1991-09-11
FI111268B (fi) 2003-06-30
DE4124468B4 (de) 2010-10-28
EP0816413B1 (en) 2005-06-08
IE912697A1 (en) 1992-02-12
AU8143091A (en) 1992-02-27
MY108621A (en) 1996-10-31
ATA151591A (de) 1996-10-15
IL99007A0 (en) 1992-07-15
FI20011189A (fi) 2001-06-05
DK0469520T3 (da) 1998-09-23
JP3137368B2 (ja) 2001-02-19
JPH0641279A (ja) 1994-02-15
IL99007A (en) 1994-12-29
ITRM910553A0 (it) 1991-07-23
ES2112259T3 (es) 1998-04-01
PT98491B (pt) 1997-12-31
AT402503B (de) 1997-06-25
CA2048200A1 (en) 1992-02-02
FI913641A (fi) 1992-02-02
HUT59837A (en) 1992-07-28

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees